History

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The Association of Clinical Scientists was formed in 1949 by a group of physicians and scientists, led by F. William Sunderman, Sr, MD, PhD (shown below), from the various fields of laboratory medicine. The organization was initially called the "Clinical Science Club," whose logo is shown above. During its early years, the members held informal meetings and helped to organize workshops and seminars in the United States, Great Britain, and Puerto Rico. The membership and activities of the organization gradually expanded, so the members decided to become incorporated as the "Association of Clinical Scientists." In 1957, the Association received a charter from the State of Pennsylvania as a non-profit scientific and educational corporation.


Compiled History of the Association

Contributors:

William Sunderman, M.D., Ph.D
Herbert Derman, M.D
Jeno E. Szakacs, M.D.
Irene E. Roeckel, M.D.
Donald T. Forman, Ph.D
Edward E. Morse, M.D
Richard H. Gadsden, Ph.D
Ernest M. Walker, Jr., M.D., Ph.D
Donald J. Cannon, Ph.D
Frederick Muschenheim, M.D

Byron A. Myhre, M.D., Ph.D.
Joseph A. Knight, M.D.
John Savory, Ph.D.
Filiberto Cavazos, M.D
James J. Humes, M.D.
F William Sunderman, Jr., M.D
John V. Klavins, M.D., Ph.D
Ludolph van der Hoeven, M.D,Ph.D
Chris Vlahides
Zimmie Davis

Contributions Compiled by:

Robert L. Hunter, M.D., Ph.D.


ACS Logo

History of The Association of Clinical Scientists
"Omnia mutantur, nos et mutamur in illis."
(All things change and we change with them)


1949 - 1998


The Early Days in the Founding of the
Association of Clinical Scientists
William Sunderman Sr., M.D., Ph.D., Sc.D.

An historian of clinical science in years to come may well be astonished at the explosive burst of scientific activity that emanated from clinical laboratories around the middle of this century. He will be puzzled by the frequent incompatibilities that developed between the disciplines of anatomic pathology and clinical pathology with its high degree of specialization and fragmentation in diverse fields. He will be impressed with the progress of clinical chemistry as evidenced by the accelerated increase in scientific publications.

By 1949, the field of chemistry had begun to exert a dominant role in the specialty of clinical pathology. This led to the foundation of a subgroup within the American Society of Clinical Pathologists which became known as the "Friends of Clinical Chemistry." Regrettably, a number of outstanding clinical chemists were not admitted to this subgroup since they held only Ph.D. degrees and an M.D. degree was a requirement at that time for membership in ASCP. Robert P. MacFate, Ph.D. was a professor at the University of Illinois and the director of the chemical laboratory at the University Hospital. I held somewhat similar responsibilities at the Pepper Laboratory of the Hospital of the University of Pennsylvania which was affiliated with the Department of Research Medicine. Our mutual scientific interests over the years developed into a close friendship. Since Bob was not a member of the Friends of Clinical Chemistry, I undertook to organize a Clinical Science Club which admitted both Ph.D.s and M.D.s into its membership. The founding club consisted of approximately twenty-five dedicated scientists with primary interests in laboratory medicine. Most of them were affiliated with medical schools. I served as the president of the Club, and Bob MacFate served as secretary. Our dedicated, peripatetic group met five times a year (bimonthly during the academic year) on a Friday and Saturday weekend at a medical center with which one or more of the members were affiliated. The host for each meeting was responsible for the preparation of a formal scientific program and visits to the analytical and research laboratories of his institution.

The Clinical Science Club proved to be an outstanding success. Very few of the members missed any meeting. I attended every one.

The American Board of Pathology was founded in 1936 and held its first meeting on July 19 of that year. Frank W. Hartman, M.D. became the president and asked me to give the Board examinations in clinical chemistry. I could not become a full member of the Board since I held certification in internal medicine, and the American Medical Association did not permit dual certification at that time. This AMA ruling was finally changed. I became certified in clinical pathology and a full member of the American Board of Pathology in 1944.

From experience gained in giving American Board of Pathology examinations, it had become apparent that pathology residents at that time were not being trained in the fundamental procedures of analytical chemistry, such as weighing of chemicals, calibration of pipets and the preparation of standard solutions, etc. Our dedicated band of Clinical Science Club members resolved to minimize these deficiencies in resident training in clinical chemistry and to further high professional standards of performance.

At the 1953 meeting of ASCP, the Friends of Clinical Chemistry, in conjunction with the Clinical Science Club, decided to organize a workshop that would enable directors of clinical laboratories to acquire a firsthand knowledge of clinical chemical procedures. It was further decided to schedule the workshop as a special feature of the 1954 ASCP meeting, which was to be held in conjunction with the International Congress of Clinical Pathology in Washington, D.C., September 6 to 11,1954. In organizing the workshop, we had no precedent to guide us. All plans had to be evolved de novo.

After World War II, Vernon E. Martens, M.D. was assigned by the Navy for training duty in my laboratory at the University of Pennsylvania. While in this tour of duty, we undertook investigative studies together, published papers, and cultivated a warm friendship that has continued over the years. After leaving the University, Dr. Martens became director of laboratories at the National Naval Medical Center in Bethesda. From this position, he was able to make arrangements to hold the first Workshop in Clinical Chemistry in his laboratories. The proximity of Bethesda to Washington made this arrangement most advantageous.

The topic chosen for the first workshop was "Clinical Hemoglobinometry." This topic was selected since (1) hemoglobin at that time was the most frequently measured component of blood, and (2) national surveys had revealed marked discrepancies in the results of hemoglobin measurements throughout this country and abroad. lnaccuracies in hemoglobin measurements had become conspicuous during World War II. For example, I found that normal hemoglobin values in England were approximately one gram less than in the United States and that this was caused by an error in the standardization of British Haldane hemoglobinometers. The fact that an error of one gram of hemoglobin per 100 ml of blood remained undetected for decades was recognized as a sad reflection on the status of clinical hemoglobinometry. It had been shown that these discrepancies were due to several factors: improper methods for blood collection, incorrectly calibrated pipets, contaminated reagents, poor analytical techniques, continuance of obsolete colorimetric methods that utilized artificial standards and, perhaps most important, the lack of agreement of parameters (extinction coefficients, oxygen capacities, carbon monoxide capacities, iron measurements) upon which accepted standards of reference might be based.

Elaborate preparations were made for the organization of the workshop. I was chosen to be the director and Dr. Martens, the honorary director. In England, the title "honorary" means that services are delivered without pay. In that context, both Dr. Martens and I should have been so designated. The faculty members for the workshop were chosen chiefly from the Clinical Science Club membership and members of the staff at the Naval Medical School.

At the 1953 meeting, it was decided to hold preliminary planning sessions periodically up until the time of the workshop. Since the ASCP did not appropriate funds for our workshop undertaking, the faculty members were obliged to pay their own traveling expenses. Fortunately, the workshop staff were members of the Clinical Science Club. This Club later became incorporated as the Association of Clinical Scientists. In order to minimize traveling expenses, planning sessions were scheduled to coincide with the meetings of the Clinical Science Club. More than six planning sessions were held in Chicago, Philadelphia, and Washington at which every procedure for the workshop was reviewed in meticulous detail.

Great praise must be given to the National Naval Medical Center and to Dr. Martens and his staff for their wholehearted, enthusiastic cooperation in our endeavor. The Navy Medical School provided the printing and design of the Workshop Manual. An elaborate color plate was prepared and printed for the identification of the absorption bands of hemoglobin derivatives. The audio-visual aids department of the Navy was especially helpful in producing four motion picture sound films in color for the workshop exercises. I made at least a half dozen trips from Philadelphia to Bethesda to supervise the filming. The titles given to the films were: "Preparation of Reagents," "Measurement of Iron and the Preparation of an Iron Calibration Curve," 'The Measurement of Total Iron in Whole Blood," and "The Measurement of Oxyhemoglobin in Blood”.

A few years ago, I took the opportunity of reviewing the workshop films. Although several decades have elapsed since their filming, the procedures are still timely, useful, and instructive. Directors of clinical laboratories might be well advised to review and undertake the basic standardization depicted for the 1954 workshop and to place less reliance on commercially prepared hemoglobin standards.

The Navy Medical School was most generous in permitting the use of the student laboratory facilities and equipment. Owing to the limitations of space, only 120 fellows of the Society could be accepted for the workshop, although 350 had applied. The selection of participants was determined geographically and by the postal date on the application envelope. The geographical selection by state was made with the hope that those attending would return to their communities and set up similar programs for their colleagues who did not have the opportunity to participate.

In retrospect, it can be presumed that the popularity of the workshop might have been attributed in part to the provision that there would be no registration fee and that admission to the workshop exercises would be free. In fact, it had become known throughout the membership that no charges would even be made for such minor items as coffee and doughnuts during the recess periods and for transportation between the National Naval Medical Center and the Shoreham Hotel.

Since additional instrumentation was required for the 120 participants and 30 instructors, commercial companies were solicited for the loan of the instruments. The Coleman Company graciously provided 25 photometers; the Brinkman Company furnished 20 hand spectroscopes; and more than 20 analytical balances were loaned by the local laboratory supply houses.

The Workshop day started at 0745 on the morning of September 8, 1954, when Navy buses arrived at the Shoreham Hotel to transport the participants to the auditorium of the National Naval Medical Center. After receiving greetings from Admiral L. Stone, Commanding Officer of the Naval Medical Center, the Workshop began with the viewing of the four films depicting in detail every procedure which each participant would undertake. Following the moving pictures, each participant was supplied with a white laboratory coat and assigned to one of six groups, each group rotating in succession through the assigned laboratory exercises. The participants were admonished to undertake every bit of the detailed work outlined in the Manual with their own "lily white" hands.

Two three-hour laboratory sessions were scheduled for the exercises: 0945 to 1245 and 1400 to 1700. A group photograph was taken at 1245, and an hour (1300 to 1400) was allotted for lunch at the Officers Mess Hall.

At the conclusion of the laboratory exercises, each participant was presented with a certificate. A number of spontaneous, highly laudatory comments were made by the participants. The hope was fervently voiced that our initial workshop would mark the beginning of a new era in continuing education.

The National Naval Medical Center then graciously presented me with a handsomely framed larger than life-size portrait (3 x 4 feet) and copies of each of the four sound films produced for the workshop. These gifts were given to ASCP as mementos for the Society's archives. The workshop exercises ended at 1830 when the buses left for the Shoreham Hotel.

As a result of the enthusiastic response from the participants of the first workshop, the American Society of Clinical Pathologists by official action resolved to establish workshops in clinical chemistry as an annual activity of the Society and to provide for the development of workshops in other fields of our specialty. In addition, it was requested that a condensed version of the Hemoglobin Manual be published in the American Journal of Clinical Pathology.

The scientific achievement of the first workshop not only portended to the continuance of the workshop type of program but also led to the recognition in other countries of its educational value. As a consequence, the faculty of the first workshop, with the cooperation of the Departments of State and the Navy, accepted an invitation to present the Hemoglobinometry Workshop at the Royal Army Medical College in London in 1957 followed by a brief workshop at the University Medical College in Brussels, Belgium.

In the early days, some of the members of the Clinical Science Club encountered difficulties with the Internal Revenue Service in deducting expenses for attendance at meetings. Since the name of our group included the word "Club", some districts of the IRS insisted that a club was essentially social and that the travelling costs were not deductible. As a consequence, the Clinical Science Club became formally incorporated as a non-profit scientific organization in 1956 under the title of Association of Clinical Scientists. The seal of the Clinical Science Club, with its spray of lilies continued as the emblem of the Association. The lily emblem emanated from my frequent remarks that to be a clinical scientist, one had to work with his/her "lily white" hands.

The Association of Clinical Scientists – 1954

Meeting Number 1. - Sept 8, 1954; Shoreham Hotel, Washington, DC; US Naval Medical Center, Bethesda, MD (Workshop on Clinical Hemoglobinometry)

Meeting Number 2. - Nov 19-20, 1954; Bellevue-Stratford Hotel; Jefferson Medical College; Philadelphia, PA 

The Association of Clinical Scientists - 1955

Meeting Number 3. - April 1-2, 1955; Kenmore Hotel; Harvard Medical School; New England Deaconess Hospital; Boston, MA

Meeting Number 4. - Oct 7-8, 1955; Shoreham Hotel, Washington, DC: US Naval Medical Center, Bethesda, MD (Workshop on Blood Glucose)

Meeting Number 5. - Dec 9-10, 1955; Drake Hotel; University of Chicago, Argonne Cancer Research Hospital; Chicago, IL

HISTORICAL POTPOURRI 1956-1960

The Constitution of the Clinical Science Club was adopted at lunch at the Arlington Hospital, Arlington, VA., on April 6, 1956. Only the evening before, at dinner, had a committee of unknown composition been appointed to write a constitution. Back in the bayou we have an expression, "You backing up, you, if you waiting on me!". That committee was not backing up! On October 6, 1956, at the Bethesda Naval Officers' Club the decision was made to incorporate as a non-profit corporation.

Three interesting events occurred at the March 1-2, 1957 meeting in Chicago. Dr. F. William Sunderman, Jr. distributed urine "...containing various porphyrins...", presumably not his own but the record is not clear. For the first time, new members were initiated into the Association in a ceremony devised by a Ritual Committee composed of Citadel graduates. And finally, the Associations' beautiful illustrated diploma was displayed for the first time by President F. William Sunderman, Sr. On its seal was the motto of the Association, "Omnia Mutantur, Nos et Mutamur". The origin of our motto is of classical interest. It is part of the complete sentence, "Omnia mutantur, nos et mutamur in illis." " All things change and we change with them." It is attributed to Lothair I, King of the Lombards, and grandson of Charlemagne, circa 840 AD, by one Matthias Borbonius. Borbonius in turn, is quoted by Janus Gruterus in a 1612 book of German poetry. Our roots go deep.

With the name changed from Clinical Science Club to Association of Clinical Scientists, Articles of Incorporation were approved in the Court of Common Please of Philadelphia County, Pennsylvania, on March 11, 1957. The incorporators were F. William Sunderman, Sr. and Jr., Robert P. MacFate, Gonzalo E. Aponte, and George F. Stevenson. The original officers were Dr. Sunderman, Sr., President, Dr. Vernon E. Martens, Vice-President, Dr. Robert P. MacFate, Secretary and Treasurer. Dr. George F. Stevenson and Dr. Gerald S. Dean were also members of the Board of Directors.

The Executive Committee in Washington, D. C. on September 28, 1957 accepted an offer by President Sunderman, Sr., '... to provide an appropriate award each year to ..." a Fellow who has demonstrated outstanding zeal in the pursuit of clinical science." The Executive Committee insisted, with Dr. Sunderman abstaining, that the award be known as the Sunderman Award. This action was then supplemented by the creation of a Diploma of Honor which might "... be presented to scientists who have made meritorious contributions to the furtherance of clinical science...". The Executive Committee then chose Frank W. Konzelmann to receive the Sunderman Award, and Dr. Claude P. Brown to receive a Diploma of Honor. Both awards were formally presented at the Orpheus Club in Philadelphia on December 13,1957.

The Sunderman Award is an engraved silver goblet which is cherished by its recipients. In the early days the recipient was expected to make an Award Oration. Dr. Konzelmann's Oration was entitled, "Clinical Chemistry, Its Effect Upon the Accuracy of the Diagnosis of Disease." The custom of Award Orations has continued to the present and their titles have been preserved in minutes or programs except for 1958,1960,1962, 1969,1974, 1979,1984 and 1985. In 1959, Earl Wert spoke on "The Training of Medical technologists". Only Bob MacFate has the unique distinction of having been designated 'Clinical Scientist of the Year' on two occasions: 1964 and 1969.

The Workshop Concept:

A previous chapter has told the Story of the development of the workshop concept by Dr. F. W. Sunderman, Sr., from his experience on the American Board of Pathology. In a personal aside I shall confess that as a resident in pathology when Dr. Sunderman was on the Board I was in mortal fear of this examiner in clinical chemistry. Rumor had it that only one in three passed chemical pathology.

The workshop concept began with pedagogic symposia at the annual meetings of the American Society of Clinical Pathologists (ASCP) in 1949 (glucose) and 1950 (clinical hemoglobinometry). These eventually led to physical workshops where Dr. Sunderman insisted that "pathologists get their, lily-white hands dirty at the bench" performing fundamental analytic chemical procedures. Large facilities would be necessary for such benchwork and fortuitously Capt. Vernon E. Martens, MC, USN, was Director of Laboratories at the national Naval Medical Center in Bethesda, MD.  Dr. Martens, a former student of Dr. Sunderman, Sr., obtained the support of the Surgeon General of the Navy, Rear Admiral B. W. Hogan, MC, USN, to place the Navy's facilities at Dr. Sunderman's disposal for the first ASCP Workshop on Clinical Hemoglobinometry, September 8, 1954, during the International Congress of Clinical Pathology in Washington, DC.

The enthusiastic response of the 120 participants and 30 faculty members led not only to the creation of an ASCP Council on Clinical Chemistry but also to repeat workshops at the Bethesda Naval Medical Center in 1955 (glucose), 1956 (Serum Proteins) and 1957 (Serum Cations). When the Navy was no longer able to provide its facilities the Association of Clinical Scientists appointed Dr. Sunderman, Sr., to be its Director of Education in October 1958.  Planning began immediately for the Associations' first applied seminar which was to combine benchwork with lectures and demonstrations. The site selected was the Washington Hospital Center, Washington, DC, where Dr. Martens was now Director of Laboratories. The first applied Seminar on Lipids and Steroid Hormones in Clinical Medicine was conducted on October 9-11, 1959. The seminar was an overwhelming success with 126 registrants and a faculty of 39. The Association of Clinical Scientists' first publication was the Proceedings of the First Applied Seminar in book form edited by Drs. Sunderman, Sr. and Jr., in 1960.

On November 4-5, 1960, the second Applied Seminar on "Measurements of Exocrine and Endocrine Functions of the Pancreas” was conducted at the Washington Hospital Center. Participation was even greater with 158 registrants and a faculty of 45. Once again the proceedings were published in book form edited by the Drs. Sunderman.

And so, the Association entered the 1960's firmly established as a society of scholars dedicated to the application of new scientific knowledge to clinical medicine. Its members had created the workshop as an educational tool for professions of any attainment level and matured the concept into applied seminars combining the theoretical and the practical. It had begun its journey into scientific publication and had demonstrated that good fellowship and conviviality enhance the learning process. All this had been accomplished according to Aesop's fable about the fly which alighted on the axle of a driving chariot wheel. The fly proclaimed, "What dust do I raise!" We flies have accomplished much on Bill Sunderman's axle.

The Association's Ambiance and Amity, 1956-1960

The five years of 1956 through 1960 were both gestational and formative for a nascent professional society. The Clinical Science Club matured into a larger group of multi-disciplinary scientists together pursuing learning. The pursuit was the ambient care but what made it unique was the embracing cloak of amity. Science of the highest, good fellowship most genial!

The amity of 1956-1960 is illustrated by the frequency with which members visited each other’s laboratories at meeting times, and by recalling banquets and speeches. Bob McFate was a raconteur nonpareil whose orations included “Salusrities I have Met" (Dec. 8, 1956) and "The Philosophy of Wine" (July 15, 1957). It was Bobs' practice to regale the membership with a Secretary-Treasurer's report buried among chains of colorful- and off-color stories and one-liners. It was this author's custom at those times madly to take notes despite eyes blurred by tears of laughter. The notes still exist but this is probably not the place to record them. Perhaps I shall will them to the Association's archives.

The most remarkable example of Association conviviality occurred at the meeting in Albany, N.Y., March 3-5, 1960. At the time, wine was not a generally appreciated sign of sophisticated taste in the United States.  To acquaint Americans to the subtleties of oenology California had created a Wine Advisory Board. This Board arranged the Association banquet which was preceded by wine tasting and a movie on the use of wines in cooking. All the dishes served at the banquet were either cooked in wine or served in wine. And each course was accompanied by a different appropriate wine or champagne. A truly civilized banquet was planned.

What was not planned however was a snow, sleet and ice storm which paralyzed transportation from the Mississippi to the Atlantic and from the Gulf of Mexico to Canada. As a result only 18 members and 10 guests were able to grope, slip and slide into Albany. The banquet attendance had been projected on the experience of the two immediately preceding Association's registrations of 56 and 126.

The wearers of the maroon and gold rosettes rose to the occasion. Simple courtesy to the host wine Advisory Board of California required that full measures of appreciation be demonstrated by the valiant few who represented so many. And so they did! The Advisory board sustained no return shipping Charges for the products brought to Albany. The genteel minutes of the meeting omit mention of the robust camaraderie of the clinical scientists. They mention "grand hospitality" and that "Members then made plans to 'plow out of the snow drifts' and return home."

The groundwork had been laid for the future meeting in Louisville to study the chemistry of fermentation.

Science and Learning

The subjects presented at the meetings of the Association during this five-year period impressively fulfilled its Constitution's objective of enhancing the professional development of clinical scientists. At the April 1956 meeting, there were papers on serotonin and the new technology of isotopes in clinical medicine. Dr. Donald Frederickson, a pioneer in the correlation between diet and inheritance in coronary artery disease spoke on "Seven Lipids, Techniques and Clinical Evaluation."

In March 1957, Wallace H. Coulter presented his groundbreaking invention, "High Speed Particle Counter and Cell Size Analyzer." Continuous flow electrophoresis and measurement of TSH in normal and endocrinopathic patients were presented in December 1957. May 1958 brought papers on DNA analysis in tumor cell nuclei and several papers in toxicology in the clinical laboratory.

Two famous contributors to clinical enzymology spoke to the Association in October 1958. Felix Wroblewski, who with John Ladue introduced transaminase in the diagnosis of myocardial infarction, spoke on enzyme measurements in body fluids. Oscar Bodansky of phosphatase renown discussed the new phenomenon of automation in the clinical laboratory. In Mobile, in February 1959, Dr. Morris Schaeffer from the Communicable Disease Center (CDC) discussed virology and the clinical pathologist. The next year, Dr. Schaeffer moved to New York City to begin the regulation of laboratories which culminated in the Clinical Laboratory Improvement Act of 1967 (CLIA).

The record of the Association’s scientific advancements and technologic innovations was continued at the March 1960 meeting when two new concepts were advanced. Dr. Philip Levine reported "The Protective Action of ABO Incompatibility in Rh Hemolytic Disease," and Dr. David S. Gerbarg and Mr. John J. Hofler demonstrated the first functional interpretation of human heart sounds by a computer.

In addition to the science, the Association presented significant learning experiences to its members through a variety of distinguished dinner and banquet speakers.  In March 1, 1957, a speaker from military intelligence, Dr. Richard Mossey, discussed "The Explosive Middle East". It was the very day that U.N. was debating free and innocent passage in the Gulf of Aqaba and the Straits of Tiran. The Union League Club of Philadelphia has been the site of many Association memories. On December 14, 1957, George Pownall Orr, Esq., spoke on "The Voyage of the Welcome" the ship on which William Penn and Bill Sunderman, Jr.'s ancestor sailed to this country in 1681.

A decidedly military turn in our banquet addresses occurred in Mobile in February 1959.  First, Mr. Ralph G. Holberg, Jr., Spoke about "The Confederate Defenses of Mobile, 1861 to 1865". The next night, Dr. Norborne R. Clarke spoke on "Firearms and Philosophy: U.S. Military Rifles, 1774 to 1946".  At the third banquet, the subject was "Military Medicine in the Space Age", by Col. Robert H. Holmes, MC, U.S.A.

At the final banquet of this demi-decade in November 1960, Col. Joe M. Blumberg, MC, U.S.A., the Deputy Director of the Armed Forces Institute of Pathology, addressed the Association on "Medicine in the U.S.S.R."

1956

Meeting Number 6. - April 6-7, 1956; Raleigh Hotel; Arlington Hospital; Washington, DC (Adoption of Constitution), Laboratories of F.B.I. Georgetown University Renal Laboratory (artificial kidney).

Meeting Number 7. - Oct. 5-6, 1956; Shoreham Hotel, Washington, DC; U.S. Naval Medical Center, Bethesda, MD

(ASCP Workshop on Serum Proteins)

Meeting Number 8. - Dec 7-8, 1956; Bellevue-Stratford Hotel; Jefferson Medical College; Philadelphia, PA. Haskell Laboratory for Toxicology and Industrial Medicine of Du Pont Co, at Newark Delaware; Jefferson Medical College; Institute for Cancer Research and the Lankeman Research Institute at Fox Chase, Philadelphia

President - F William Sunderman MD PhD; Vice-President and Historian - Vernon E Martens MD; Secretary-Treasurer Robert P MacFate PhD

1957

Meeting Number 9. - March 1-2, 1957; Sheraton Hotel; Northwestern University Medical School; Chicago, IL and Abbott Laboratories, N. Chicago; Coleman Instrument Co., Maywood, IL (Workshop on Electrical Basis of Instrumentation)

Meeting Number 10. - July 15, 1957; Royal Army Medical College, London, England (International Workshop on Hemoglobinometry)

Meeting Number 11. - Sept 27-28, 1957; Shoreham Hotel, Washington, DC: US Naval Medical Center, Bethesda, MD (ASCP Workshop on Serum Cations)

Meeting Number 12. - Dec 13-15, 1957; Bellevue-Straford Hotel; Jefferson Medical College; Philadelphia, PA and Research laboratories of Wyeth laboratories, Radnor, PA:) Lankeman Hospital, Philadelphia

Secretary-Treasurer Robert P. MacFate PhD; President - F. William Sunderman, M.D., Ph.D.; Vice President - Vernon E. Martens, M.D.; Executive Committee - George F. Stevenson, M.D., and Gerald S. Dean, M.D. CLINICAL SCIENTIST OF THE YEAR (The Sunderman Award) Frank W Konzelmann MD; Award Oration, "Clinical Chemistry, Its Effect Upon the Accuracy of the Diagnosis of Disease." DIPLOMA OF HONOR Claude P Brown MD

1958

Meeting Number 13. - May 9-11, 1958; Sheraton-Lincoln Hotel; Indianapolis General Hospital; Eli Lilly Co.; Indianapolis, IN

Meeting Number 14. - Oct. 10-12, 1958; Park-Sheraton Hotel; New York, NY; Warner Chilcott Laboratories, Morris Plains, N.J.

President - Vernon E Martens MD; Vice-President - George F Stevenson MD; Secretary- Treasurer Robert P MacFate PhD; Executive Committee - F.W. Sunderman, Sr., M.D., Ph.D.; Herbert Derman, M.D. Clinical Scientist of the Year (The Sunderman Award), Oscar G Costa Mandry MD; Award Oration, "The Development of Clinical Science in Puerto Rico" DIPLOMA OF HONOR F William Sunderman MD PhD

1959

Meeting Number 15. - Feb 26-March 1, 1959; Holiday Inn; Mobile Infirmary; Mobile, AL

Meeting Number 16. - Oct. 9-11, 1959; Sheraton-Park Hotel; Washington Hospital Center; Washington, DC, Seminar, "The Lipids and Steroid Hormones in Clinical Medicine."

President - George F Stevenson MD; Vice-President - Herbert Derman MD; Secretary- Treasurer Robert P MacFate PhD; Executive Committee - F.W. Sunderman, M.D., Ph.D.; Gerald S. Dean, M.D.; Malcolm L. Barnes, Vernon E. Martens, M.D. CLINICAL SCIENTIST OF THE YEAR (The Sunderman Award) Earl B Wert MD, Award Oration, "The Training of Medical Technologists." DIPLOMA OF HONOR Robert P MacFate PhD

1960

Meeting Number 17. - March 3-5, 1960; DeWirt Clinton Hotel; NY Stare Health Department, Division of Laboratories and Research; Albany, NY

Meeting Number 18. - Nov. 4-6, 1960; Shoreham Hotel; Washington Hospital Center; Washington, DC (Seminar)

(Measurements of Exocrine and Endocrine Functions of the Pancreas.

President - George F Stevenson MD; Vice-President - Herbert Derman MD, Secretary- Treasurer Robert P MacFate, PhD; Executive Committee - F.W. Sunderman, M.D., Ph.D.; Vernon E. Martens, M.D.; Malcolm L. Barnes. M.D., George F. Stevenson CLINICAL SCIENTIST OF THE YEAR (The Sunderman Award) Asher Yaguda MD; 

DIPLOMA OF HONOR Hans N Naumann MD

1961

The Association of Clinical Scientists – 1961

Meeting Number 19. - April 14-16, 1961; Bellevue-Stratford Hotel; Jefferson Medical College; Philadelphia, PA

Meeting Number 20. - Oct 27-29, 1961; Shoreham Hotel; Washington Hospital Center; Washington, DC (Measurements of Thyroid and Parathyroid Functions)

President - Herbert Derman MD

Vice-President - Earl B Wert MD

Secretary-Treasurer Robert P MacFate PhD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR George F Stevenson MD

DIPLOMA OF HONOR Vernon E Martens MD

Meeting Number 19. - April 14-16, 1961; Bellevue-Stratford Hotel; Jefferson Medical College; Philadelphia, PA

The spring meeting of the association was held in Philadelphia, Pennsylvania upon the invitation of Dr. F. W. Sunderman, Sr. A good account is given in the minutes of the 19th meeting, April 14-16, 1961. Interesting to note, the guest lecture: "Pneumocystis carinii Infections in Men and Experimental Animals" by Walter H. Sheldon, M.D., and Professor of Pathology at Johns Hopkins University in Baltimore.

Meeting Number 20. - Oct. 27 -29, 1961; Shoreham Hotel; Washington Hospital Center; Washington, DC.  "Measurements of Thyroid and Parathyroid Function in Clinical Medicine".

The Applied Seminar, was presented at the Washington Hospital Center in Washington, DC on October 27-29. The Shoreham Hotel served as headquarters and for the social programs.

The availability of radioisotopes of iodine and their applications in evaluation of thyroid functions permitted the introduction of new methodologies.  Nuclear medicine laboratory units started up all over the country. The applied seminar was not only timely but was conducted by leading scientists from laboratories who were designing the newer methods. Staff members at the U .S. Naval Medical School Nuclear Medicine Lab and at various laboratories of NIH in Bethesda as well as several outstanding clinicians and scientists were among the instructorial staff. Dr. Evelyn B. Mann who started her investigations before 1949 on maternal thyroid function with Jack Peters by describing butanol extractable iodine (BEl) and thyroid binding globulins in pregnancy and in infancy was among the seminar staff. Also, J. B. Hazard of Cleveland, W. H. Perloff of Philadelphia and others were leading scientists of the time.

The arrival of the Chicago contingent to prepare for the workshop was greeted by cheers of the old Navy guard already at work with Vern Martens. It was true comradery and much delight that came with Bob MacFate, George Stevenson, Joe Sherrick, George Smothers, and Jerry Dean. They brought laughter and stories to make hard work feel like play.

The seminar banquet featured two speakers. Under the title “Pyramidally Extinct”, Colonel James E. Ash, M.D., by then a legend in American pathology, organizer and first director of the Armed Forces Institute of Pathology, presented his collection of pictures of English tombstones, cemeteries and countryside accompanied by his witty and philosophical comments that delighted all at the banquet.

Bill Sunderman, Sr. spoke of his experiences on his visit to Russia titled "Clinical Science Behind the Iron Curtain". The contrast between the laboratories in the USSR and those in the USA was shown to be great due to poor equipment and lack of support for clinical research in the USSR.

The annual Association banquet was a remarkable and happy event. Dr. Herb Derman, president, served as roast-master. Bob MacFate contributed some of his "mother-in-law" stories, but the serious business was celebrating Dr. Vernon E. Martens for his many contributions through the years to the Association of Clinical Scientists. Vern as a founding member of the Association and its host to all the applied seminars to that date was presented with a diploma of honor by Herb Derman. Dr. F. W. Sunderman, Sr., Director of Education, then presented the Sunderman Award as the "Clinical Scientist of the Year" to Dr. George F. Stevenson. The award oration of Dr. Stevenson was titled "Famous Thyroids". It was a remarkable performance with great historical depth still reflected in his chapter in the published proceedings of the seminar under the title of "Evaluation of Thyroid and Parathyroid Function". The seminar was attended by 187 clinicians and scientists.

The Association of Clinical Scientists – 1962

Meeting Number 21. - April 6-8, 1962; Sheraton Hotel; Northwestern University Medical School; Chicago, IL

Meeting Number 22. - Oct 25-28, 1962; Statler-Hilton Hotel; Washington Hospital Center; Washington, DC; (Hemoglobin, Its Precursors and Metabolites)

President - Earl B Wert MD

Vice-President - Joseph C Sherrick MD

Secretary-Treasurer Robert P MacFate PhD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Herbert Derman MD

DIPLOMA OF HONOR Harrison H Leffler MD

Meeting Number 21. - April 6-8, 1962; Sheraton Hotel; Northwestern University Medical School; Chicago, IL

The meeting was entitled "Recent Advances in Clinical Science", although it might have been entitled "New Frontiers in Clinical Science".  This was the year when the first practical autoanalyzer became available and Coulter's electronic cell counter was state of the art.  Electronic data processing was in its infancy and certainly not available for hospital laboratories.

The scientific program for the meeting organized by Drs. Joseph C. Sherrick, Bob MacFate, Gerald S. Dean, George F. Stevenson, and George W. Smetters was a true window to the future of clinical science.  Three seminars were presented:  1) "The Application of Computer Systems to Medical Sciences"; 2) "Automatic Analyzers"; 3) "The Use of the Electron Microscope in Clinical Research".

On Friday afternoon, April 6, the computer seminar included a visit to the IBM Computing Center of Northwestern University, at the time one of the largest university computing centers.  A demonstration and successive discussions explained the fundamental nature of the device and its future applications in the general hospital.  The moderator and organizer of this trip was Dr. Joseph C. Sherrick.  This was an entirely new field at the time, rather futuristic when even years later Hospital data processing centers were of punch card technology.

On Saturday, April 7, Dr. Samuel A. Levinson moderated the session on "The Use of Automatic Analyzers".

Dr. Gerald S. Dean moderated the third seminar, "The Use of the Electron Microscope in Clinical Research".  Ultrastructure of liver in pathologic conditions and ultrastructure of glomerular changes in renal disease were presented by Drs. Geoffrey Kent and Benjamin H. Spargo, respectively.  The final scientific session on Saturday afternoon was moderated by George F. Stevenson, M. D. and included a number of varied presentations such as the improvement of autopsy reporting by the use of special forms and appropriate for the times (the Cuban missile crisis) the "Feasibility of Protection when the Bomb Strikes".

At the seminar banquet on Friday, April 6, F. William Sunderman, Jr., M. D., President of the Association, served as toastmaster.  The banquet address was given by Jim Thomas on fishing and hunting.  Jim Thomas was living the life of an outdoorsman.  He fished and hunted from the Bahamas to the Arctic Circle, Canada to Cuba.  He had recorded his outdoor experience and telecast on weekly color television programs in Chicago.  At the banquet, he showed some of his films on fishing in the Northern part of Canada.

Saturday night's banquet at the Sheraton Chicago Hotel included cocktails and dinner.  Dr. Earl B. Wert served as toastmaster and Dr. John Ott presented his time lapse photography on "Growth Responses of Plants and Animals to Variations in Wave Length of Light Energy".  His presentation was both informative and enjoyable.

The meeting closed with a planning session for the applied seminar in clinical science to be held in Washington, DC on October 26-28, 1962.

Meeting Number 22. - Oct. 25-28, 1962; Statler-Hilton Hotel; Washington Hospital Center; Washington, DC; (Hemoglobin, Its Precursors and Metabolites)

Upon the invitation of Dr. Vernon Martens, the two-day applied seminar on "Clinical Pathology of Hemoglobin, its Precursors and Metabolites" was presented at the Washington Hospital Center.  The timely subject and many outstanding scientists, speakers, and demonstrators attracted 261 registrants.

The banquets were attended by 270 guests.  The Friday evening banquet held at the Statler Hilton Hotel was preceded by a cocktail party.  Dr. Arthur T. Hertig, Shattuck Professor of Pathological Anatomy, Harvard Medical School, gave a most interesting talk on "Chance and Her Favors".  His illustrations of the earliest embryonic annidation were a historical first.

The annual banquet of the Association was held on the 27th, Saturday evening at the Statler Hilton Hotel.  Dr. Earl B. Wert, President, served as toastmaster.  A Diploma of Honor for outstanding achievement in clinical science was awarded to Dr. Harrison H. Leffler of Washington, DC and the Sunderman award to the "Clinical Scientist of the Year" was presented to Dr. Herbert Derman of Kingston, NY.  Dr. Wert made the presentation of the suitably engraved silver goblet and Dr. Derman responded with his award oration.

An indication of the success of the seminars were the numerous applications for membership out of whom 36 were recommended by the Credentials Committee.

The Association of Clinical Scientists – 1963

Meeting Number 23. - April 25-28, 1963; Sheraton Hotel; Louisville Medico-Chirugical Society; Louisville, KY

Meeting Number 24. - Oct 24-27, 1963; Statler-Hilton Hotel; Washington Hospital Center; Washington, DC; (Serum Proteins and the Dysproteinemias)

President - Joseph C Sherrick MD

Vice-President - Charles L Blumstein MD

Secretary-Treasurer Robert P MacFate PhD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Malcolm L Barnes MD

DIPLOMA OF HONOR Dora A Newson MD

Meeting Number 23. - April 25-28, 1963; Sheraton Hotel; Louisville Medico-Chirurgical Society; Louisville, KY

The spring meeting in Louisville is long remembered not only by the 35 members and guests (a total of 88) but the entire membership through the many photographs shown and stories told the following years.  This is the meeting which remains in the annals of the Association as the pinnacle of conviviality and amity.  Upon the invitation of Dr. Malcolm M. Barnes, a spring meeting was held in Louisville with the accustomed high quality of scientific sessions.  Extraordinary were Dr. Barnes' arrangements for "the dispensing the Southern hospitality".  On Thursday, April 25, members and guests made an all day tour of the Bluegrass Thoroughbred Horse Farms.  Nashua and other famous horses were seen; the grave of Man-O-War was visited.  On Friday, a break from the scientific session was followed by lunch at the Brown-Forman Distillers Corporation and a luncheon address: "The Comparison of Enzyme Actions in Distilling and Human Physiology".

Another first at this meeting was the recognition of the Ladies Committee on the printed program.  A tour of historical Farmington was arranged for the ladies by Mrs. Malcom L. Barnes.  The home was designed by Thomas Jefferson and built by Judge John Speed in 1810.

The Association banquet on Friday, April 26, was held at the Sheraton Hotel, Dr. Malcolm Barnes serving as toastmaster.  Entertainment was provided by the Henry Miles Jug Band and an unusually fine barbershop quartet known as the Club House Four.  The County Sheriff was in attendance and several members received appoint-ments as Deputy Sheriffs.  Bob MacFate, our secretary, received an illuminated sign to be displayed at all future meetings of the Association.

On Saturday morning, the scientific session continued until lunch time.  Luncheon was enjoyed at Churchill Downs, following a tour of the Derby Museum and a talk on "Science and the Thoroughbred" by Dr. Browny Leach.  The afternoon was spent "at the races".  On Saturday evening, the banquet was in cooperation with the Louisville Medical/Chirurgical Society.  Banquet address was given by Dr. Oscar Auerbach who spoke on "The Smoking Problem".

The Governor of Kentucky honored by appointments as Kentucky Colonels:  Drs. Sherrick, Sunderman, Auerbach, and MacFate.

A short business meeting on Saturday morning ended understandably with rising vote of thanks to Dr. and Mrs. Malcolm L. Barnes for their most generous hospitality. 

Ever hear a Spoon Band?  We did at the Association’s “Happy Hour”.  Dr. Malcomb Barnes arranged for a spoon band to entertain us.  How three people hitting two spoons together (bowl to bowl) could make such harmony, we will never know.  The first and only time that we have heard that part of our Southern musical heritage.  (Mel and Zimmie Davis)

Meeting Number 24. - Oct. 24-27, 1963; Statler-Hilton Hotel; Washington Hospital Center; Washington, DC; (Serum Proteins and the Dysproteinemias)

The annual meeting and a two-day applied seminar on "Serum Proteins and the Dysproteinemias" was presented at the Washington Hospital Center under the direction of Dr. F. William Sunderman, Sr.  The host for the meeting was Dr. Vernon E. Martens.  The outstanding scientific program was attended by 274 scientists and their accompanying wives and guests brought overall attendance to 370.  The applied seminars attracted more and more clinicians and scientists as it is documented by the attendance and by applications for membership in the Association of Clinical Scientists.  At the conclusion of this seminar, 52 scientists applied for membership including several who played important roles later in advancing the cause of the Association.  Those to be mentioned are Dr. Ludolph H. van der Hoeven and Dr. Richard R. Gadsden. 

The edited proceedings of the scientific sessions were published, the fifth volume in a series edited by Drs. Sunderman.

The Friday evening seminar banquet was held at the Statler Hilton Hotel.  The banquet address was given by Dr. James F. Haggerty, Chief, Research Grants Branch of the National Cancer Institute, Bethesda, MD.  Dr. Haggerty gave a most interesting talk on "The Role of the Scientist Administrator in Research".

The annual banquet of the Association of Clinical Scientists, Saturday evening, October 26, 1963, was chaired by Dr. Joseph C. Sherrick, President of the Association.  A diploma of honor for outstanding achievement in clinical science was awarded to Dr. Dora A. Newson of Edmonton, Alberta, Canada.

The Sunderman award to the "Clinical Scientist of the Year" was presented to Dr. Malcolm L. Barnes by Dr. F. William Sunderman, Sr.  Dr. Barnes responded with his award oration, "Applied Clinical Scientist".

The Association of Clinical Scientists – 1964

Meeting Number 25. - May 1-3, 1964; Bellevue-Stratford Hotel; Jefferson Medical College; Philadelphia, PA

Meeting Number 26. - Nov 13-15, 1964; Statler-Hilton Hotel; Washington Hospital Center; Washington, DC (Clinical Pathology of the Serum Electrolytes).

President - Charles L Blumstein MD

Vice-President - F William Sunderman Jr MD

Secretary-Treasurer Robert P MacFate PhD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Robert P MacFate PhD

DIPLOMA OF HONOR Philip H Geisler MD

Meeting Number 25. - May 1-3, 1964; Bellevue-Stratford Hotel; Jefferson Medical College; Philadelphia, PA

1964 was a landmark year.  On Friday, May 1st, a conducted tour of the Wyeth Laboratories in Radnor, PA was hosted by Dr. George E. Farrar, Director of the Medical Services Division.

In the meantime, the ladies held a luncheon in honor of Mrs. F. William Sunderman.  This was followed by a tour of several of the historical homes of Philadelphia.

The scientific session held on Saturday, May 2, at the Bellevue/Stratford Hotel was filled with papers of great interest.

A banquet was held on the evening of May 2nd at the Union League of Philadelphia in recognition of Dr. F. William Sunderman's many contributions to the Science of Medicine.  The events are recounted by Bob MacFate in his secretary's report:

“This was an appropriate time to honor Dr. Sunderman, since it was the 15th anniversary and the 25th meeting of the Association, of which he was the first President.  It was also the 15th anniversary of the Proficiency Testing Service, a system of clinical laboratory quality control, which he instituted.

Dr. George F. Stevenson of Rockville, MD served as toastmaster.  The Right Reverent Oliver J. Hart, formerly Bishop of the Episcopal Diocese of Pennsylvania, gave the invocation.

Present were representatives of 15 of the learned institutions in which Dr. Sunderman has taken an active part.  After dinner, each spoke briefly on his activities in their organization. 

In addition to these speakers, the audience included representatives of corporations and groups for whom Dr. Sunderman has served as consultant.  The attendance at the banquet was approximately 200.

In a lighter vein, several of the Founding Fellows of the Association laid aside all matters of state and formality and indulged in some degree of levity at Dr. Sunderman's expense.

Dr. Herbert Derman spoke of Dr. Sunderman's activities in the many seminars and symposia presented under his direction.  He emphasized that Dr. Sunderman's vast knowledge of the allied scientific fields enabled the presentation of programs of unusually wide scope and value.

Dr. Robert P. MacFate reviewed his accomplishments in the world of music, especially his devotion to the violin.  The review began with early youth and continued to the present.  Special mention was made of various string quartets and solos that had been presented.

Dr. Vernon E. Martens referred to the international seminars presented under Dr. Sunderman's guidance.  His devotion to the literature promoted the presentation to him of a special copy of the "Handbook of Chemistry and Physics".

Dr. Joseph C. Sherrick briefly reviewed Dr. Sunderman's activities in various local and national scientific societies.

Dr. Earl B. Wert reviewed his college days and activities as a preceptor in clinical pathology.

Music throughout the evening was presented by the DeLancey Quartet.  This was climaxed by the rendition of the last movement of the Brahm's Piano Quartet, opus 25.

General Joe Blumberg presented Dr. Sunderman with an engraved Honors Medal on behalf of the Armed Forces Institute of Pathology.

Dr. Robert P. MacFate, on behalf of the Association, presented a bound volume of testimonial letters.  Approximately 400 congratulatory letters were especially bound in blue calf skin, imprinted with gold.  The volume contained two dedicatory pages handsomely illuminated in gold and appropriate colors by an internationally renowned illuminator.

Dr. Charles L. Blumstein presented Dr. Sunderman with an engraved gold-chased silver goblet, similar to that which is awarded annually by the Association to the "Clinical Scientist of the Year".  This goblet is awarded for outstanding zeal in the pursuit of clinical science.  The Executive Committee of the Association felt that this was an appropriate time to present this richly deserved award to Dr. Sunderman.

Dr. Sunderman responded to these accolades with appropriate remarks.  He referred to the formation of the Clinical Science Club and the eventual incorporation of the Association of Clinical Scientists.  He dwelt especially on the philosophy behind the objectives of the Association.

At the conclusion of Dr. Sunderman's remarks, Dr. Frank Konzelmann, recipient of the Association's Award for 1957, proposed a toast to Dr. Sunderman, in which he was joined by all present.

The evening concluded with the guests coming to the dais to personally greet and congratulate Dr. Sunderman."

Meeting Number 26. - Nov. 13-15, 1964; Stratford-Hilton Hotel; Washington Hospital Center; Washington, DC (Clinical Pathology of the Serum Electrolytes).

Upon invitation of Dr. Vernon E. Martens, the annual meeting and a two-day applied seminar on "The Serum Electrolytes in Clinical Medicine" was presented at the Washington Hospital Center in Washington, DC.  The outstanding instructorial staff and demonstrators in the comprehensive program organized under the directorship of Dr. F. William Sunderman attracted 320 registrants to the seminar.  Many of those in attendance at the banquet were accompanied by their wives, families and guests.  This was the largest meeting to that date of the Association, attesting to the foresight, organizational skills and scientific leadership of our Director of Education.

The seminar banquet on Friday at the Statler Hilton Hotel featured Mr. Robert N. Hilkert, first Vice-President of the Federal Reserve Bank of Philadelphia with his banquet address "The Art of Managing".

The annual banquet of the Association was held Saturday evening at the Statler Hilton.  A diploma of honor for outstanding achievement in clinical science was awarded posthumously to Dr. Philip H. Geisler.  Mrs. Geisler was in attendance to receive the diploma.  Dr. Harold L. Stewart, Chief of the Pathology Laboratory, National Cancer Institute, gave the citation.  Dr. Geisler was especially prominent in the activities of the Association of Clinical Scientists, having served on the faculty of four applied seminars of the Association and having presented scientific papers at many meetings of the Association.

The highlight of the banquet was the presentation of the Sunderman award to the "Clinical Scientist of the Year" to Dr. Robert P. MacFate.  Dr. F. William Sunderman, Sr. made the presentation of a suitably engraved silver goblet.  Dr. MacFate responded with his award oration titled "Quo Vademus". 

The much beloved and admired secretary-treasurer of the Association after expressing his gratitude spoke for a few minutes on the marked contrast between learning new facts about the scientific world and learning those things involved with one's own personal life.

He then reviewed the early history of the Clinical Science Club and the Association of Clinical Scientists.  He included pictures and anecdotes relating to the many meetings, workshops, seminars, dinners, and travels of the Association.

In his annual report, Bob MacFate reviewed the two outstanding meetings of the past fiscal year and made special mention of the banquet held on the evening of May 2, 1964 at the Union League in Philadelphia in recognition of the contributions of Dr. F. William Sunderman to the science of medicine.  He concluded, however, that “more important to us than Dr. Sunderman's contributions to the science of medicine have been his contributions of inspiration and hard work on behalf of this Association.  We can never fully repay our debt of gratitude.”  This contributor has heard this sentiment said over and over again by the membership in many different forms, but never expressed so succinctly as by Bob MacFate.

The Association of Clinical Scientists – 1965

Meeting Number 27. - April 29-May 2, 1965; Statler-Hilton Hotel; St. Albans Naval Hospital; New York, NY

Meeting Number 28. - Nov 11-14, 1965; Statler-Hilton Hotel; Washington Hospital Center; Washington, DC (Clinical Pathology of Infancy)

President - F William Sunderman Jr MD

Vice-President - Joe M Blumberg MD

Secretary-Treasurer Robert P MacFate PhD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Joseph C Sherrick MD

DIPLOMA OF HONOR Oscar Kanner MD

Meeting Number 27. - April 29-May 2, 1965; Statler-Hilton Hotel; St. Albans Naval Hospital; New York, NY. The spring meeting of 1965 in New York presented special opportunities to enjoy the city's unique social and professional opportunities by the membership. 1965 was the year of the New York World's Fair, it was the year of "Hello Dolly" on Broadway and it was the year for an enthusiastic staff at St. Albans New York Naval Hospital to host the meeting. Thursday evening, the 29th, 35 members and guests were entertained by Carol Channing as "Dolly" and were introduced to their hosts, Vice Admiral H. Deuterman and Captain John Albrittain at the Broadway theatre. Admiral Deuterman who hosted a visit by our members to the United Nations and later gave the banquet address with a big smile and relief confined to Dr. Szakacs his surprise and complete delight that meeting the clinical scientists turned out to be an unexpected pleasure rather than his expected meeting with a dour group of scientists who could not tear themselves away from test tubes. Great fun was had by all and next a whole day visit to the New York World's Fair dedicated as "Clinical Scientists Day" was memorable. Some of the exhibits as Disney's "It's a Small World" are still delighting many in Orlando's Disney World. The Fair's symbol was a tower of light. In honor of the Association of Clinical Scientist Day, Dr. F. William Sunderman and Bob MacFate were asked to turn the light on and introduce Clinical Scientists Day at the New York World's Fair. The scientific events took place at the U.S. Naval Hospital in St. Albans, New York.  Tuberculosis and diseases caused by atypical mycobacteria still required specialized centers for treatment in 1965. St. Albans Naval Hospital was one of those centers for the Navy. A group of presentations focused on tuberculosis, its diagnosis and on chemotherapeutic drugs used for treatment of MTB and atypical organisms causing widespread disease. Presentations were supplemented by an exhibit on laboratory identification of organisms, the various mycobacteria and the pathology associated with each of the specific groups. The exhibit was prepared by the laboratory Staff under the direction of Phyllis Warren, head of the microbiology department. Hosting the meeting generated a great deal of enthusiastic activities by the pathology staff. Seven presentations and three exhibits were-prepared by the host group. Just as enthusiastic support characterized the participation of the consultants, several of whom later became distinguished members of the association. Studies on clotting mechanisms of blood were discussed by Koloman Laki of factor XIII fame, by Donald G. McKay, by Fredrick F. Becker, and by Leon Sussman. Other timely subjects were presented by Meyer W. Melicow, Herb Derman, Irene Roeckel, and Elias Cohen. And indeed timely for the frontiers of technology in 1965 was "Electronic Data Processing" illustrated in an exhibit by Elemer Gabrieli. Even the hospital's historical room was dedicated to the meeting featuring a collection of historical laboratory equipment and microscopes dating from the 1760's. True to the tradition of Navy support of the meetings in its earlier years, three additional papers were contributed by pathologists in uniform and Vern Martens, by this time retired, was among the audience. The local committee for arrangements received a gracious helping hand from the secretary, Dr. Robert MacFate. Bob's attention did not escape any the least important details. He personally inspected even the food to be served at the banquet, delighting the chef with his advice and appreciation of good dishes.

The president, Bill Sunderman, Jr., was happy with the large number of scientists and guests attending the Spring meeting, a total of 167.

Meeting Number 28. - Nov. 11-14, 1965; Statler-Hilton Hotel, Washington Hospital Center, Washington, DC (Clinical Pathology of Infancy).

Applied seminars became very popular in the first half of the 60's as they filled a real need of practicing clinical scientists. Attendance nearly doubled between 1961 and 1965. The "Clinical Pathology of Infancy" seminar was attended by 351 physicians and scientists and the social program by many additional guests. Proceedings of five previous applied seminars published became standard text in hospital laboratories and in medical libraries starting with "Lipids and the Steroid Hormones in Clinical Medicine" presented in 1959.

The "Applied Seminar of the Clinical Pathology of Infancy" was presented at the Washington Hospital Center on invitation of Dr. Vernon Martens, by now a well established location for the seminars. The spacious auditorium and available classrooms were luxuriously adequate for both lectures and demonstrations in methodology and for hands-on workshops. Dr. Sunderman, Sr. and his scientific council assembled a real star-studded faculty for this seminar. The program reads as a Who's Who in American science. Of 67 speakers and demonstrators, 36 were members of the Association. The program was organized under the following headings: congenital biochemical disorders in infancy, endocrinology and metabolism in infancy, clinical pathology of systemic diseases in infancy, and cytogenetics in infancy. Each group of lectures was followed by demonstrations in methodology. By now, the participants were accustomed to various types of laboratory exercises including chemical reactions, electronic instrumentations, but this time, they were amusing themselves with scissors in their hand cutting out chromosome spreads from 8 x 10 prints and preparing karyotypes.

Two banquets were held at the Washington Hilton Hotel, the "Seminar Banquet" on Friday evening and the "Annual Banquet of the Association" on Saturday. A diploma of honor for outstanding achievement in clinical science was awarded posthumously to Dr. Oscar Kanner. The citation was given by Dr. Herbert Derman. Mrs. Kanner was in attendance to receive the diploma.

The "Sunderman Award to the Clinical Scientist of the Year" was presented to Dr. Joseph C. Sherrick. Dr. F. W. Sunderman, Sr. made the presentation of a suitably engraved silver goblet. Dr. Sherrick responded with his award oration titled "Recreational Habits of the Clinical Scientist".

On conclusion of the seminar on November 14, the annual business meeting was called by Dr. Sunderman, Jr. Dr. Bob MacFate gave his report as secretary-treasurer stating that at the beginning of that meeting the total membership was 290. There were 40 candidates for membership to be acted upon. Among the candidates were Dr. Don T. Forman, Dr. Michael Lubran, Dr. Daniel Seckinger, and Dr. Leon Sussman, each of whom made and are continuing to make contributions to clinical science and to the Association. Nevertheless, caution was voiced by Bob MacFate in his report in reference to proposal for membership. "As a member of this association, it is your privilege to invite others to join with us. Be certain that they are truly interested in the work we are doing. Remember that as an association, we do not attempt to represent any one profession or any one group of scientists...... Accordingly, our choice of candidate for membership need be based only on the value of these persons to the Association."

The Director of Education, F. Sunderman, Sr., announced the subject for the next seminar, "The Clinical Pathology of the Liver and the Biliary Tract", to be held at the-Washington Hospital Center on October 20-23, 1966. 

An important administrative decision announced was that the Internal Revenue Service approved the tax-exempt status of the association this year.

The Association of Clinical Scientists – 1966

Meeting Number 29. - April 29-May 1, 1966; Palmer House; Chicago Board of Health Laboratories; Chicago, IL

Meeting Number 30. - Oct 20-23, 1966; International Inn; Washington Hospital Center; Washington, DC; (Laboratory Diagnosis of Liver Diseases)

President - Jeno E Szakacs MD

Vice-President - Gerald S Dean MD

Secretary-Treasurer Robert P MacFate PhD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Vernon E Martens MD

DIPLOMA OF HONOR Evelyn B Man PhD

During the four-year period, 1966-69, our Association continued the established pattern of holding the Fall meetings in the nation's capital, Washington, D.C., and the Spring meetings at various sites. The Fall meeting continued to be focused on a specific topic; and Spring sessions covering a variety of subjects under the title, "Recent Advances in Clinical Science”. On the national scene during this period, Lyndon Johnson continued in the Office of President, having assumed the presidency in 1963, following the tragic assassination of John F. Kennedy. During most of these years the attention of many Americans was directed toward Southeast Asia where the very unpopular war in Viet Nam continued to escalate. By 1968, some 500,00 American troops were involved In the fighting and anti-war protests were mounting in intensity. In March of 1969, Johnson made a televised speech in which he announced that he would not seek re-election. This was a most remarkable turn of events, considering that he had been re-elected in 1964 by a landslide margin, defeating Barry Goldwater, losing only in Goldwater's home state of Arizona.

Meeting Number 29. - April 29-May 1, 1966; Palmer House; Chicago Board of Health Laboratories; Chicago, IL.

The Spring meeting in 1966 was held in Chicago, home environs of the then Association President, Gerry Dean, and of our long-time and highly popular Secretary- Treasurer, Bob McFate. Many of us had been introduced to clinical biochemistry by the widely read text authored by Levinson and McFate. Highlights of the meeting included visits to the Institute for Biomedical Research of the American Medical Association and to the new Division of Laboratories of the Chicago Board of Health, where Bob McFate was Director. The association banquet was held at the host hotel, The Palmer House. Following dinner, a most informative talk was presented by Mr. Ralph A. Bowreder, former Executive Secretary of the National Society for Medical Research, entitled, " A View Inside the Strange Movement Known as Antivivisection". Honored at that meeting were perennial Washington Host, Dr. Vern Martens as Clinical Scientist of the Year, and Dr. Evelyn Man, who received the Diploma of Honor.

Meeting Number 30. - Oct. 20-23, 1966; International Inn; Washington Hospital Center; Washington, DC; (Laboratory Diagnosis of Liver Diseases).

November 1966 found the Association once again in Washington with the International Inn as Headquarters Hotel and the extensive facilities of the Washington Hospital Center as meeting venue. The Seminar topic, "Laboratory Diagnosis of Liver Diseases", attracted a total number of 375 members and guests. The instructional staff of 71 speakers and demonstrators included the outstanding scientists of the country in this field. Under the heading of "Fundamental Considerations", virtually all aspects of the microscopic anatomy of the liver, physiologic functions, including normal and abnormal were presented in great detail. Techniques for the measurement of normal and abnormal metabolites were described and demonstrated. The President, Dr. Jeno E. Szakacs, presided, at the Seminar Banquet on November 11th where the Honorable Harold C. Kessenger, well-known lecturer and humorist, spoke on "The Sunny Side of Main Street". At the Association Banquet on November 12th, Dr. Vern Martens acknowledged his award with a talk entitled, "Grapes of Wrath".

The Association of Clinical Scientists - 1967

Meeting Number 31. - May 4-7, 1967; Robert Meyer Hotel, Orlando; Kennedy Space Center, Cape Canaveral; University of Florida College of Medicine, Gainesville, FL

Meeting Number 32. - Nov 2-5, 1967; Shoreham Hotel; Washington Hospital Center; Washington, DC (Laboratory Diagnosis of Kidney Diseases)

President - Gerald Dean MD

Vice-President - Howard Quittner MD

Secretary-Treasurer Robert P MacFate PhD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Gonzalo E Aponte MD

DIPLOMA OF HONOR Joseph B Hartney MD

Meeting Number 31. May 4-7, 1967; Robert Meyer Hotel, Orlando; Kennedy Space Center, Cape Canaveral; University of Florida College of Medicine, Gainesville, FL.

At the invitation of Dr. F. William Sunderman, Jr., the Spring 1967 meeting was held in Orlando, FL, May 4-7. The headquarters hotel was the Robert Meyer Motor Inn and field trips to Cape Kennedy and to the University of Florida College of Medicine in Gainesville were meeting highlights. At Cape Kennedy, various aspects of bioastronautics were presented in a series of talks by staff members working in support of the Manned Space Flight Program.  Following luncheon, tours were conducted including the Bioastronautics Operational Support Unit and various Launch Complexes. Members came away with a much-enhanced understanding of the scientific and medical aspects of Manned Space Travel. At Gainesville, following a series of lectures on a variety of, interesting topics, tours were provided of both the clinical laboratories of the Medical School and of those at the newly opened Veterans Administration Hospital. (These tours reminded many of the early days of the Association, when all enjoyed visits to one another's laboratories to compare methodology, equipment and protocols). Following an extensive series of lectures on May 6th at the Host Hotel covering such varied topics as Whipple's Disease, Recent Advances in Cancer Chemotherapy, and the Effects of Hyperbaric Oxygenation on Tumor Metastases, members and guests were ready for the Association Banquet. The banquet was chaired by Association President, Dr. Gerald S. Dean, and the Banquet Address delivered by CAPT Elgin C. Cowart, MC, USN was titled "Life in the Medical Museum or Job to Fun in One Step". An appropriate title as he was Director of the Armed Forces Medical Museum.

Meeting Number 32. - Nov. 2-5, 1967; Shoreham Hotel; Washington Hospital Center; Washington, DC (Laboratory Diagnosis of Kidney Diseases).

In the Fall of 1967, the Association meeting was again held in Washington, D.C. This time, the Host Hotel was the America, in reality the venerable Shoreham, temporarily re-named since American Airlines was involved in its management at that time. Nonetheless, it was easy to be certain that you were visiting the Shoreham because the irreverent, piano playing satirist, Mark Russel, was entertaining in the cocktail lounge. The Seminar was titled "Laboratory Diagnosis of Kidney Diseases", and the scientific sessions were held once more at the Washington Hospital Center where the topic was covered in exquisite detail by the 81 member distinguished faculty. One is hesitant to single out any specific presentation from among such a galaxy of distinguished speakers. Suffice it to say that the entire program was truly superior. The Seminar Banquet was held on November 3rd at the hotel where Herbert Harrison, distinguished Humorist from Buffalo, NY spoke on "Just What the Doctor Ordered". The Association Annual Banquet, held on Nov. 4th featured presentations by President Gerald S. Dean, M.D. to James B. Hartney, M.D. the Diploma of Honor, and Gonzalo E Aponte, M.D. - Clinical Scientist of the Year. Unfortunately, both of these beloved friends died within a very few years following this meeting.

The Association of Clinical Scientists - 1968

Meeting Number 33. - May 16-19, 1968; Sam Peck Inn; University of Arkansas School of Medicine; Little Rock, AR

Meeting Number 34. - Nov 7-10, 1968; Shoreham Hotel; Washington Hospital Center; Washington, DC (Laboratory Diagnosis of Diseases Causes by Toxic Agents)

President - Howard Quittner MD

Vice-President - James J Humes MD

Secretary-Treasurer Robert P MacFate PhD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Joe M Blumberg MD

DIPLOMA OF HONOR Dorothea M Gilmore MD

Meeting Number 33. - May 16-19,1968; Sam Peck Inn; University of Arkansas School of Medicine; Little Rock, AR.

At the invitation of Dr. Howard Quittner, the Spring 1968, meeting of the Association was held in Little Rock, Arkansas. Thursday was devoted to a visit to the Winthrop Rockefeller (Win-Rock) Farms on Petit Jean Mountain near Morrilton, Conway County, Arkansas. Here is located the Head-quarters Division and the Rock-Win Division, totaling some 2,700 acres. (The Rockefeller interests also own the Carlisle Division consisting of 17,000 acres in the eastern delta half of Arkansas, and the Oklahoma Division of 10,000 acres.) The Win-Rock farms have developed a large herd of the Santa Gertrudis beef cattle, a breed originally developed by the King Ranch of Texas. These huge animals combine the hardiness of the Brahman with the profitable meat-producing qualities of the Shorthorn. They have found that crossing Santa Gertrudis bulls to commercial cows will, in the first generation, produce heavier, more profitable steers. Artificial insemination is being used extensively. One outstandingly productive bull can breed up to 10,000 cows a year. Frozen with liquid nitrogen to 320 deg. F below zero, semen can be preserved for long periods of time which permits long-time experimentation under controlled conditions and the servicing by one bull of cows in any part of the world.

Medical research is being assisted by experimental surgery on newborn calves. The program included the study of pulmonary vascular changes after aortic- pulmonary shunts. Following luncheon at Mather Lodge in Petit Jean State Park, a visit was made to the Museum of Automobiles where the collection rivals that in the Henry Ford Museum at Greenfield Village in Michigan. Here, among the many antiques, is to be found one of the very first "automobiles" ever constructed - a steam wagon completed in 1866 by Richard Dudgeon.

On Friday, the scientific program began at the University of Arkansas Medical Center. In one of the first talks we were introduced, many of us for the first time, to the very dangerous Brown Recluse Spider. The bite of this arachnoid, rather common in the Southwest, produces a hemorrhagic, necrotizing lesion which is most difficult to treat. (In recent years the habitat has become more extensive - a colleague in North Florida recently was bitten and was incapacitated for several weeks.)  Also on that program, there was a very enlightening presentation on Pulmonary Cryptococcosis now much more common due to AIDS. In the afternoon, extensive tours of the University clinical laboratories were conducted.

That evening, many attendees visited the "Old West Dinner Theatre" and were delighted by a presentation of the long-running New York hit, “The Fantastiks".

On Saturday, the program continued with several interesting topics including automated methodology in hematology and chemistry and Atomic Absorption Spectrometry for the measurement of calcium and magnesium. At luncheon on that day, we were joined by respected senior member, Claude Brown of Philadelphia. Dr. Brown, then in his late 80s, was asked if he planned to stay for the post-meeting fishing trip on the Arkansas River. He replied that he was unable to do so, and that he had to return to his laboratory!  When asked what he knew about the local fishing prospects, he stated that he had no contemporary knowledge but that he found it to be quite good when he was stationed nearby at Ft. Smith 50 years ago in 1918!

That evening, the Annual Banquet was held with Association President, Dr. Harold Quittner as Toastmaster. The address was given by Dr. Meyer Melicow of Columbia University and was Titled "Medicine in Art" a subject in which he was very well versed being a successful painter in his own right. 

Our post-meeting, float fishing trip to Bull Shoals was arranged by Dr. Howard Quittner. The guide gave up on Mel and Zimmie Davis. But others did well using canned kernel corn. Mel's and my special memory, besides camp life, is one of Malcomb Barnes presenting the cook with a crate of fresh strawberries with instructions for true southern short cake.  Malcomb was a man who appreciated good food, good bourbon and a good story. (Mel and Zimmie Davis)

Meeting Number 34. - Nov. 7-10, 1968; Shoreham Hotel; Washington Hospital Center; Washington, DC (Laboratory Diagnosis of Diseases Causes by Toxic Agents).

November 7-10, 1968 found us once again in Washington, DC, with scientific session at the Washington Hospital Center, hosted by Dr. Martens, and The Shoreham serving as headquarters hotel. The seminar title, a most ambitious one, was Laboratory Diagnosis of Diseases Caused by Toxic Agents. Included in the discussions were virtually every conceivable agent, chemical, physical, biological and environmental and affecting virtually every organ system! This was not a program for hypochondriacs or the faint-hearted. The various methodologies for the detection and quantitation of these agents were presented in great detail. Included were gas chromatography, Infra-red spectroscopy, Atomic Absorption Spectrometry, Thin-layer chromatography and Mass spectrometry. In addition, several presentations covered the diagnosis and treatment of the effects of the various agents on humans.

At the Annual Banquet, Chaired by Association President, Dr. Howard Quittner, the Diploma of Honor was presented to Dorothea McClure Gilmore of Clearfield, Penna. The Sunderman Award to Clinical Scientist of the Year to Gen. Joe M. Blumberg, MC USA. Gen. Blumberg's Award Oration was titled “Medicine in Tropical Africa".

The Association of Clinical Scientists - 1969

Meeting Number 35. - April 24-27, 1969; Malaga Inn; Mobile Infirmary; Mobile, AL

Meeting Number 36. - Nov 6-9, 1969; Mayflower Hotel; Washington Hospital Center; Washington, DC (Laboratory Diagnosis of Endocrine Disorders)

President - James J Humes MD

Vice-President - Alfred H Free PhD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Robert P MacFate PhD

DIPLOMA OF HONOR Samuel A Levinson MD

Meeting Number 35. - April 24-27. 1969; Malaga Inn; Mobile Infirmary; Mobile, AL

The 1969 Spring Meeting was held in Mobile, Alabama, April 24-27 at the invitation of Dr. Earl Wert of the Mobile Infirmary, long-time member and Past-President. The host hotel was the Malaga Inn and the weather was perfect. 

The scientific sessions began on Thursday morning and included "Clinical Applications of a Desktop Computer" (How much have computer influenced our lives and our practices in the past 30 years). Also presented was a paper on "Metabolic Thyroid Disorders". Luncheon that day was provided aboard the Battleship "Alabama", veteran of World War II and now permanently berthed in Mobile Bay. Lunch was followed by tours of the ship and a discussion of the medical facilities given by Dr. Herb Allen, who supervised the reconstruction of the "Sick Bay".

The scientific program continued in the afternoon and included a presentation titled "Computer Science and the Modern Hospital", by Mr. Robert Gelinas, Director IBM Computer Section, Mobile Infirmary. Once again, our Association kept members informed and at the cutting edge of scientific development. Dinner that evening was provided at the exclusive Bienville Club atop a local high-rise. The after-dinner talk was presented by Mr. Edwin C. Bramiett, Administrator, Mobile Infirmary and was titled, "Some Thoughts on Physicians and Hospitals, Past, Present and Future". The scientific program resumed on Saturday with several interesting papers including Biochemical Screening Programs - Results and Problems.

That afternoon, we were privileged to be able to visit the beautiful Bellingrath Home and Gardens. Mr. Bellingrath, who had the first Coca-Cola franchise for the State of Alabama, was quite successful. He built this House and Gardens on a river bend just north of Mobile and they have become showpieces of the South. The beautiful mansion is, in reality a museum, containing innumerable dolls, silverware, china and artifacts of every type. The Gardens are most extensive containing shrubs and flowers of every variety and one of the most extensive collections of azaleas in the country. Our guide to the Gardens was an elderly Negro gentleman, who, I believe, lacked formal education, but who knew both the common name and the scientific name, most all in Latin, of everything growing there. A most up-lifting experience! That evening, following a seafood buffet, we were entertained by Mr. Nelson E. Grubbs, State Toxicologist for Alabama, who spoke on "Moonshine and Romance: A Documentary on Shinny Whiskey." 

Saturday morning was again devoted to scientific papers, and, the afternoon to tours of the laboratory facilities of the Mobile Infirmary. That evening, a short bus ride took us to the Grand Hotel at Point Clear, a resort and golfing community. This showplace of the Deep South is on the east shore of Mobile Bay halfway to the Gulf, where spectacular sunsets are observed. Dinner that evening was followed by a most entertaining talk by a regional history buff, Mr. Martin J. Johnson who related many amusing anecdotes.  He stated that the understanding of a particular sentence, depends in many instances, upon where the emphasis is placed. For example with regard to the Battle of Mobile Bay -" Damn the torpedos, full speed ahead! or DAMN!, TORPEDOS! full speed ahead.

At the Business Meeting on April 27, the members were surprised by Dr. Bob McFate's announcement that he would no longer be a candidate for the office of Secretary-Treasurer, which he had held for 20 years. Having retired from practice and moved to Pentwater, MI, he recommended that a younger individual be chosen. President Humes appointed the nominating committee for the next year and directed that a new Secretary-Treasurer be appointed as soon as possible.

Meeting Number 36. - Nov. 6-9, 1969; Mayflower Hotel; Washington Hospital Center, Washington, DC (Laboratory Diagnosis of Endocrine Disorders)

Returning to Washington, D. C., the Fall 1969 Meeting of the Association was held Nov. 6-9 with the host hotel, The Mayflower, and the Scientific Seminar, once again at the Washington Hospital Center, hosted by Dr. Vern Martens. The Seminar, another ambitious one, was titled “Laboratory Diagnosis of Endocrine Disorders” and covered a broad spectrum of conditions. The topics discussed by the Faculty of 62 presenters included all of the endocrine glands and ranged from hypofunction to hyperfunction, with variations. Also presented in considerable detail was the effect of these abnormal states on various body organs and functions. Naturally, major portions of the program were devoted to the methodologies utilized to monitor the substances produced by these important organs. In addition to the traditional chemical methods, immunologic methods, both immunochemical and immunoradiological were presented. In addition, secondary effects in target organs were discussed.

The Annual Banquet was held at the Mayflower on Friday evening and was a Testimonial to retiring Secretary, Robert P. MacFate, Ph.D. President Humes presided and Dr. MacFate's Chicago colleague. Joseph C. Sherrick M.D. served as Toastmaster. Bob McFate’s many talents and his great influence on clinical pathology in cooperation with his friend, Sam Levinson, was remembered by his Chicago friends.  Members of the Association owe much to Bob for his hard work and for his leadership that was crucial in founding the Association of Clinical Scientists.  As the Secretary of the Association for its first 20 years, the standards he set are still being followed touching on many activities of the Association.

Quite appropriately, The Diploma of Honor was awarded to Samuel A. Levinson, M.D. Dr. McFate's response displaying his customary jovial good humor was appreciated by the entire assembly.

The activities of the Association during this three-year period were quite representative of the goals and purposes of the organization. These include the dissemination of scientific information, the introduction of new concepts and developments, and, perhaps above all, the fostering of good fellowship, and the recognition of the accomplishments of Association members. The contributions of Bill Sunderman, Sr. to achieving these goals cannot be overstated. Those of us who have had the opportunity to work with him and to assist him in some way, have been truly blessed.

The Association of Clinical Scientists - 1970

Meeting Number 37. - April 23-26, 1970; Ponchartrain Hotel; Wayne State University Medical School; Detroit, MI

Meeting Number 38. - Nov 6-8, 1970; Shoreham Hotel; Washington Hospital Center; Washington, DC (Chemical Hematology)

President - Alfred H Free MD

Vice-President - Irene E Roeckel MD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR John H Wilkinson PhD

DIPLOMA OF HONOR Oscar G Costa Mandry MD

Meeting Number 37. - April 23-26, 1970; Ponchartrain Hotel; Wayne State University Medical School; Detroit. MI.

Founding member and past president, Dr. James J. Humes, invited the Association to hold the Thirty-seventh Meeting in Detroit. Michigan, April 24 to 26, 1970. Scientific presentations updated the field for chemistry and hematology. Research contributions were made by faculty of Wayne State University during the visit to the Department of Occupational Health. The Saturday closing session discussed the impact of computer science in managing clinical laboratories and on-line computer function, today present in most clinical laboratories.

The reception and dinner at the beautiful Hotel Ponchatrain included a presentation by James Farley, the president of St. Johns Hospital.

The recreational program for scientists and their family included a special tour of the Ford Motor Company Automobile assembly Plant in Rouge River. The visit to Greenfield Village permitted viewing the unequaled collection of Americana by Henry Ford.

During the Sunday morning business meeting, 31 new members were elected to membership. President Free implemented the creation of the network of Regional Planning coordinators to assist the Director of Education in planning and organizing the annual Applied Seminars. The membership approved the creation of a journal of the Association to publish the proceedings of the Applied Seminars and papers submitted. The journal to be published bimonthly starting in January 1971. The fee of $15 for active members was approved also. Everyone was saddened that two beloved founding members, Dr. Robert P. MacFate and Dr. Claude Brown, could not attend due to illness.

Meeting Number 38. - Nov. 6-8. 1970; Shoreham Hotel; Washington Hospital Center; Washington, DC (Chemical Hematology).

The Thirty-eighth Meeting, The Applied Seminar on Chemical Hematology was held November 6, 7 and 8, 1970 at the Shoreham Hotel and Washington Hospital Center.  Among the lecturers was the leader in enzymology, Dr. J. Henry Wilkinson from London, England, an expert on enzyme measurements.  As response to being awarded the Sunderman award for Clinical Scientist of 1970, he spoke on “Education in Laboratory Medicine:  A Transatlantic Commuter's Impressions”. Lectures and demonstrations were deemed to have been the finest seminar to ever be presented by the Association. This may be reflected in 38 new members joining the Association. With the vigorous growth of the membership, financial management was streamlined. New committees appointed were A) Awards Committee to select future recipients of the Sunderman Award for Clinical Scientist of the Year and diploma of honor; B) Archives Committee to preserve records and photographs chronicling the activities of the Association, to include necrology; C) Constitution and By-laws Committee; and D) Publications Committee to further the proposed Journal of the Association.

The Association of Clinical Scientists - 1971

Beginning in January of that year, the Executive Committee was hard at work to address ways and means to launch the official journal of the Association, entitled "Annals of Clinical Laboratory Science". The effort was supported by unanimous approval by the membership. We now know that it became a great success.

Meeting Number 39. - April 22-25, 1971; Hotel Sonesta; University of Connecticut Medical School; Hartford, CT

Meeting Number 40. - Nov 11-14, 1971; Hilton Hotel; Washington Hospital Center; Washington, DC (Clinical Pathology of the Lipids)

President - Irene E Roeckel MD

Vice-President - Mel A Davis MD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Jeno E Szakacs MD

DIPLOMA OF HONOR Leon N Sussman MD

Meeting Number 39. - April 22-25, 1971; Hotel Sonesta; University of Connecticut Medical School; Hartford, CT.

The Spring Meeting in Hartford, CT. April 22-25, presented an outstanding program, with a wide range of timely topics in Clinical Chemistry, Toxicology, Microbiology, Hematology-Immunology, Enzymology and Automation. The inclusion of presentations on Laboratory Medicine in Health Care demonstrates the farsightedness of the organization, since few at that time concentrated on quality in the laboratory and its impact on health care.

This Spring Meeting was graced by an innovation on Friday night, a Musicale, introduced by F. William Sunderman, MD lecturing on "ANTONIO STRADIVARI OF CREMONA". This had special impact on the audience since Dr. Sunderman played a violin made by STRADIVARI, during the musicale. Banquet Highlights recognized Dr. Costa Mandry of Puerto Rico, who celebrated his golden anniversary of graduation from Medical School, and received the Associations Diploma of Honor. A record number of 48 new members were elected during the business meeting. The time had also come to change the Seal of the Association from "Clinical Science Club" to "Association of Clinical Science". The topic of "Clinical Pathology of the Lipids" was accepted as theme for the November Applied Seminar in Washington, DC.

Meeting Number 40. - Nov. 11-14, 1971; Hilton Hotel; Washington Hospital Center; Washington, DC (Clinical Pathology of the Lipids).

The Fortieth Meeting, the Applied Seminar on the Clinical Pathology of the Lipids was held November 12-14, 1971 at the Washington Hospital Center. 62 lecture presentations and 24 demonstrations of methodology covered the aspects of lipid chemistry and metabolism for the participants, ranging from basic consideration to the newest analytical procedures. During the Banquet, Dr. Leon N. Sussman was awarded the Diploma of Honor. Dr. Jeno E. Szakacs received the award of the Clinical Scientist for 1971.  His response:  "A Touch of Virus" recounted search for retroviruses in human tumors.

The Banquet address by Dr. Millard E. Gladfelter, Chancellor- Temple University, "Entangled by Learning" would be very timely today. The excellent meeting attracted 25 new Fellows and 4 Associate Members.

With the new Publication of the Annals of Clinical Laboratory Science in place, Mrs. Martha Brisco was introduced as Assistant to the Editor, Dr. W. Sunderman Sr.  Although anticipated that costs for the publication would exceed revenues during the first three years, unanimous Support was voted by the members.

The Association of Clinical Scientists - 1972

Meeting Number 41. - April 27-30, 1972; Holiday Inn; University of Notre Dame; Ames Co.; Elkhart, IN

Meeting Number 42. - Nov 2-5, 1972; Marriott Motor Hotel, Northwestern University Medical School; Chicago, IL (Clinical Pathology of Respiratory Diseases)

President - Mel A Davis MD

Vice-President - Leon N Sussman MD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR James J Humes MD

DIPLOMA OF HONOR Kurt M Dubowski PhD

The executive committee recommended to the membership steps to secure the success of the publication of the Annals of Clinical Laboratory Science by turning over the responsibility of publishing the journal to the Institute for Clinical Science. Any profit from the venture would be turned over to the Association.

Additional steps to assure streamlining the financial affairs included the move of the financial operation of the Annual Applied seminar as well. This partnership has proven to be most effective.

Meeting Number 41. - April 27-30, 1972; Holiday Inn; University of Notre Dame; Ames Co.; Elkhart, IN

The Forty-first meeting in Elkhart, Indiana successfully guided by the faithful members Dr. Alfred Free and his wife Helen, had for the first time so many presentations scheduled, that simultaneous sessions were needed. One had to choose between Clinical Laboratory Measurements and Clinical Interpretations.  Friday Highlights included Chamber Music after Dinner, performed by members and guests.  Sponsored by the Ames Company the Saturday evening Association Dinner was held at the Elcona Country Club. It was elaborate and sumptuous. Dr. John Mirza gave the Banquet Address.  At the Association Business Meeting, the membership supported the proposed long-range programs developed by the Executive Committee. Thirty-three new members were elected for membership.

Meeting Number 42. - Nov. 2-5, 1972; Marriott Motor Hotel. Northwestern University Medical School; Chicago, IL (Clinical Pathology of Respiratory Diseases).

The Annual Seminar on The Clinical Pathology of Respiratory Diseases was attended by 375 scientists. The excellent facilities accommodated the 77 scientific papers and 22 demonstration sessions with remarkable convenience. 

At the Annual Banquet, Kurt M. Dubowski. Ph.D. received the Diploma of Honor; James Humes, M.D. received the Sunderman Award and responded with a presentation: “The Laboratory Worker and Continuing Education”.

The special Honor conveyed by the presentation of The Gold-Headed Cane to Claude Brown, M.D. on his 97th Birthday reflected his long and faithful service to the Association.  Albert V. Crewe, Ph.D. spoke on the Observation of Single Atoms with the Electron Microscope, a scholarly, stimulating and entertaining presentation.

Saturday evening, all looked forward to the repeat of the popular musicale by members of the Association. 

At the business meeting, the financial stability of the fund balance indicated that no dues or fee changes were indicated. Thirty-three scientists and one associate joined the Association. For the first time the manual of procedures for the Applied Seminar was bound in a handy size (5.5X8.5), much easier to handle than the old format (9X11). This change was readily accepted, persisting until today.

The first group of Clinical Scientists to have a post-meeting session at the Bermuda Biological Station, left Chicago for a two-stop trip to Bermuda. It was dormitory living and cafeteria style food in a relaxed way.  As participants, we saw Bermuda from wine at the Governor's home, to a boat trip to Nonsuch Island. We did our own exploring by moped.  The front lawn of the station was the drilling site for a geological project. Core samples seemed endless and mostly lava. Drilling was still going on when we left. Wondering how far they drilled. (Mel and Zimmie Davis)

HISTORY OF ASSOCIATION OF CLINICAL SCIENTISTS (1973-1976)

(Donald T. Forman, Ph.D. and Florence Forman)

The years of 1973 to 1976 were a unique period for the Association of Clinical Scientists. A review of the activities of the Association, both scientific and social, demonstrated a forward-looking organization examining what was technically new on the horizon and its effect on the future of laboratory medicine. The Association, in its activities and publications, continued to emphasize diagnostic methodology and mechanisms of disease in its seminars. These activities were characterized by quality, breadth and depth. There were several particularly strong seminars. This included programs on laboratory diagnosis of cancer (1973), skeletal, muscular and nervous disorders (1974), drugs and toxic agents (1975) and clinical enzymology (1976). The basic objective of these seminars was to present, update and discuss the recent technology and ideas that could be expected to have an impact on the practice of clinical laboratory science.

Reviewing the program of these seminars (1973-1976) indicates the success with which this objective was reached. Most of the bioanalytical techniques and instruments that were discussed and demonstrated were routinely employed in clinical laboratories during this period. Various types of high-performance chromatography, mass spectrometry, advanced immunoassays, monoclonal antibodies, automated reaction rate analyzers, atomic absorption, automated histopathology, radiometric microbiological assays, and advanced discrete clinical analyzers were discussed and demonstrated at Association seminars (see below).

A second objective of the Association meetings and seminars was to disseminate information to a wide clinical audience in a rapid and timely manner. Consequently, the presentations and demonstrations given at the spring and fall meetings have all been published in the Association journal" Annals of Clinical and Laboratory Science" as abstracts or full papers in the year they were presented. Methodology papers and demonstrations in methodology were published each fall in a "Manual of Procedures', for that specific seminar (e.g., "Manual of Procedures for Laboratory Diagnosis of Skeletal. Muscular and Nervous Disorders', ed. F. W. Sunderman, Institute for Clinical Science, Inc., Philadelphia, PA, 1974).

Active Fellows, Associates, Emeritus members and others during the four-year period (1973-1976) numbered about 600. Both the spring and fall meetings were well attended. An important reason for the robust attendance and success of the organization and its activities during this period was the sense of collegiality and purpose the group shared. Joint social activities with the Women's Auxiliary, sharing stories both ribald and reminiscent engendered a sense of enjoyment and sociality. Our meetings and seminars were held in very special places: from Puerto Rico to Chapel Hill. For us it was the hospitality of Mina and Oscar Costa Mandry in 1976 that helped define the Association. Their gift of framed dried flowers of Puerto Rico still graces our home.

The following narrative highlights various scientific, professional and social events during the years' 1973-1976.

The Association of Clinical Scientists - 1973

Meeting Number 43. - May 3-5, 1973; Hawaiian Village Motel; St. Joseph's Hospital; University of South Florida College of Medicine; Tampa, FL

Meeting Number 44. - Nov 2-4, 1973; Shoreham Hotel; Washington Hospital Center; Washington, DC (Laboratory Diagnosis of Cancer)

President - William E Delaney MD

Vice-President - Donald T Forman PhD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Michael M Lubran MD PhD

DIPLOMA OF HONOR Alfred H Free PhD

Meeting Number 43. - May 3-5, 1973; Hawaiian Village Motel; St. Joseph's Hospital; University of South Florida College of Medicine; Tampa, FL.

Upon the invitation of Dr. Jeno E. Szakacs, the Spring Meeting of the Association of Clinical Scientists was held in Tampa, Florida on May 3-5,1973. The attendance was 206, including 118 scientists and 88 guests. Special scientific activities included tours of the clinical laboratories and research laboratories at St. Joseph's Hospital and at the Veterans Administration Hospital. The scientific sessions included 47 scientific papers covering a wide range of timely topics in clinical science. One scientific session was devoted to Viral Carcinogenesis. High points of the scientific sessions included presentations by Dr. Albert J. Dalton of the National Cancer Institute, and by Drs. Herschel Sidransky and Henry Azar of the University of South Florida School of Medicine.

On Friday evening, May 4, 1973, a delightful reception and banquet was held at the Hawaiian Village Inn. Dr. Jeno Szakacs was the Toastmaster. The banquet address on the topic "To Tampa with Love" was presented by Mr. Hampton Dunn, Editor of the "Florida Explorer". Mr. Dunn presented a lively review of the history of Tampa, and illustrated his discussion with nostalgic photographs.

On Saturday, May 5 at 5:30, the Business Meeting of the Association was held with Dr. William Delaney presiding. An important item effected was approval of the change of name of the Association Journal to Annals of Clinical and Laboratory Science.

At 8:30pm, an informal chamber music recital by Members of the Association was held at the Hotel.

Meeting Number 44. - Nov. 2-4, 1973; Shoreham Hotel, Washington Hospital Center, Washington, DC (Laboratory Diagnosis of Cancer).

The Annual Applied Seminar of the Association of Clinical Scientists was held at the Shoreham - Hotel in Washington, D.C. on November 2nd to 4th, 1973. The meeting was formally convened on November 2nd by greetings from the President of the Association. Dr. William E. Delaney, and the Director of Education, Dr. F. William Sunderman. Four hundred and sixteen scientists were in attendance.  As usual, the scientific presenta-tions were both excellent and comprehensive, including a total of 81 scientific papers and 24 demonstrations of methodology. 

On Friday evening, November 2nd, a delightful reception and banquet was held at the Shoreham Hotel, attended by 197 scientists and guests. A Diploma of Honor was presented to Dr. Alfred H. Free, in recognition of his outstanding contributions to the laboratory diagnosis of disease and his manifold services to the Association. The Sunderman award of a silver goblet and designation as "Clinical Scientist of the Year" was presented to Dr. M. Michael Lubran, in recognition of his varied and important achievements in the field of clinical science and his dynamic leadership. Dr. Lubran responded with a brief address entitled " A Pisgah View of Clinical Science", in which he forecast the dramatic changes in the organization and delivery of clinical laboratory services which may be anticipated during the next decade.

On Saturday evening, movies, slides and discussions were presented by members who had participated in the May 1972 field trip to the Bermuda Biological Station. Afterwards, a chamber music session was enjoyed by members of the Association and participants of the Seminar. 

Programs for spouses of the scientists were without structural organization.  Being asked to plan activities for the wives, Zimmie Davis found it challenging, especially from Ohio. When Dr. F. W. Sunderman. Jr. handed her blank, signed Association checks to pay the bus and tour people, he was a trusting soul. That was when Zimmie Davis decided “we needed our own auxiliary with our own funds”.  A letter to Dr. F. W. Sunderman Sr. (fondly called Pater) started the formation of the Auxiliary.  (Mel and Zimmie Davis)

The Association of Clinical Scientists - 1974

Meeting Number 45. - March 7-10, 1974; La Jolla Village Inn; Scripps Foundation; University of California Medical School; La Jolla, CA

Meeting Number 46. - Nov 8-10, 1974; Bellevue-Stratford Hotel; Jefferson Medical College; Philadelphia, PA; (Laboratory Diagnosis of Skeletal, Muscular, and Neurological Disorders)

President - Donald T Forman PhD

Vice-President - Michael M Lubran MD PhD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

GOLD-HEADED CANE AWARD F William Sunderman MD PhD

CLINICAL SCIENTIST OF THE YEAR William E Delaney MD

DIPLOMA OF HONOR Mel A Davis MD

ABRAHAM J GITLITZ MEMORIAL LECTURESHIP Klaus Schwarz MD "Elements Newly Identified as Essential for Animals."

Meeting Number 45. - March 7-10, 1974; La Jolla Village Inn; Scripps Foundation; University of California Medical School; La Jolla, CA.

Upon the invitation of Dr. M. Michael Lubran, the Spring Meeting of the Association of Clinical " Scientists was held in La Jolla, California on March 8-10, 1974. The attendance was 131, including 89 scientists and 42 guests. Special scientific activities included tours of the Clinical and Research Laboratories at the Veterans Administration Hospital and at the Scripps Clinic and Research Foundation. The scientific sessions included 51 scientific papers covering a wide range of timely topics in clinical science. One scientific session was devoted to the metabolism of trace metals. Highpoints of the scientific sessions included the first Abraham J. Gitlitz Memorial Lecture by Dr. Klaus Schwarz of the University of California, and presentations by Dr. Hans J. Muller-Eberhard and his colleagues at the Scripps Clinic and Research Foundation.

On Friday evening, March 8, 1974, a delightful reception was held at the La Jolla Village Inn. On Saturday evening, March 9, the Banquet of the Association was held at the La Jolla Village Inn. Dr. M. Michael Lubran was the Toastmaster. The banquet address was provided by Dr. A. Baird Hastings of the Scripps Clinic and Research Foundation on the topic "The Clinical-Chemical Interface of Medical Science: Its Development in this Century". Dr. Hastings' address was a memorable experience. He brought into life the spirit of the most exciting years in clinical science and the personalities of some of the towering figures of this field. Everyone agreed that Dr. Hastings' address was an experience which will never be forgotten.

The Business Meeting of the Association was held on Sunday morning, March 10, 1974. President Forman occupied the Chair. Dr. F. William Sunderman, Director of Education and Editor-in-Chief of the Annals of Clinical and Laboratory Science, reported on the activities of the Annals. He stated that the Annals was now flourishing from both scientific and fiscal viewpoints, with a substantial backlog of manuscripts and an active growth in circulation. The Annals has received critical acclaim from several sources, including the British Medical Journal. Dr. Sunderman also reported on the plans for the Twenty-fifth Anniversary and Applied Seminar of the Association, which will be held in Philadelphia on November 7-10, 1974.

About 12 women gathered in a meeting room at the Inn discussed pros and cons of an Auxiliary. Finally, the pro's won: a constitution formed, officers volunteered and the Auxiliary began.  Connie Engelstad was secretary-treasurer, Zimmie Davis, president and other officers were to be chosen.  The ladies hoped to follow in the tradition of Lou Martens and Joan MacFate by giving welcome and friendship. (Mel and Zimmie Davis)

Meeting Number 46. - Nov. 8-10, 1974; Bellevue-Stratford Hotel; Jefferson Medical College; Philadelphia, PA; (Laboratory Diagnosis of Skeletal, Muscular, and Neurological Disorders).

The meeting was formally convened on November 8th by greetings from the President of the Association, Dr. Donald Forman, and the Director of Education, Dr. F. William Sunderman. Three hundred and seventy-eight scientists were in attendance. The scientific sessions were devoted to the topic "The Laboratory Diagnosis of Skeletal, Muscular and Nervous Disorders". As usual, the scientific presentations were both excellent and comprehensive, including 88 scientific papers and 24 demonstrations of methodology.

On Friday evening, November 8th, the Twenty-fifth Anniversary Banquet was held at the Bellevue-Stratford Hotel, attended by 204 scientists and guests. Many Founding Fellows of the Association were present. A Diploma of Honor was presented to Dr. Mel A. Davis, in recognition of his outstanding contributions to the laboratory diagnosis of disease and his manifold services to the Association. The Sunderman award of a silver goblet and designation as "Clinical Scientist of the Year" was presented to Dr. William E. Delaney, in recognition of his important achievements in the field of clinical science and his dynamic leadership. Dr. Delaney responded with a brilliant and witty address entitled "Sounds of Trumpets and Other Jazz" in which he emphasized the present needs for leadership in clinical laboratory science. Dr. Herbert Derman, Toastmaster of the Anniversary Celebration, presided at a delightfully nostalgic recapitulation of the saga of the Association of Clinical Scientists with presentations by Drs. Robert MacFate, Malcolm Barnes, Claude Brown, James Humes, Gerald Dean, George Stevenson and Joseph Sherrick. Dr. Sherrick presented a gold-headed cane to Dr. F. William Sunderman, First President of the Association, in recognition of twenty-five years of continued scientific leadership. Dr. Sunderman responded with a serious discussion of the difficult dilemmas of human experimentation and the problems of governmental regulation of research in clinical science.

The Association of Clinical Scientists - 1975

Meeting Number 47. - May 2-4, 1975; Governors Inn; University of North Carolina Medical School; Chapel Hill, NC

Meeting Number 48. - Nov 7-9, 1975; Bellevue-Stratford Hotel, Philadelphia, PA (Laboratory Diagnosis and Monitoring of Disorders Caused by Drugs and Toxic Agents)

President - Michael M Lubran MD PhD

Vice-President - John Savory PhD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Howard Quittner MD

DIPLOMA OF HONOR Irene E Roeckel MD

CLAUDE P BROWN MEMORIAL LECTURESHIP Hillel J Gitelman MD "Future Shock from the Laboratory."

Meeting Number 47. - May 2-4, 1975; Governors Inn; University of North Carolina Medical School; Chapel Hill, NC. 

On Friday, May 2nd, the scientific sessions were held at the University of North Carolina School of Medicine in Chapel Hill. On Saturday and Sunday, May 3rd and 4th, the scientific sessions were held at the Governors Inn in Research Triangle Park. Dr. John Savory was Chairman of the Program Committee, assisted by Drs. William W. McLendon and Lawrence M. Killingsworth. The meeting was formally convened on May 2nd by greetings from Dr. William J. Cromartie, Associate Dean of the School of Medicine, and from Dr. William W. McLendon, Professor and Director of the Department of Clinical Laboratories. Seventy-eight scientists were in attendance. The scientific sessions were devoted to the topic "recent Advances in Clinical Science". A total of forty scientific papers were included in the program. These contributions were of splendid scientific quality and they covered a broad range of topics. Highpoints of the meeting included: (a) The Claude P. Brown Honorary Lecture on "Future Shock from the Laboratory", presented by Hillel J. Gitelman, M.D., and (b) guided tours and scientific demonstrations in diverse laboratories at the University of North Carolina Memorial Hospital and School of Medicine.

On Friday evening, May 2nd, the Association Banquet was held at the Governors Inn, attended by eighty-nine scientists and guests. The Toastmaster was M. Michael Lubran, M.D., Ph.D., President of the Association of Clinical Scientists. The Banquet Address by Dr. William W. McLendon was entitled "Medicine in Tarheelia". Dr. McLendon traced the history of medicine in North Carolina ("the Tar Heel State") from colonial days to the early years of the 20th century. Dr. McLendon's delightful address was illustrated by many interesting documentary slides and maps. Dr. McLendon's presentation was enthusiastically received and appreciated by all of the attending scientists and guests.

The intermission of the Association's Musicale gave Mel and Zimmie Davis the chance to introduce some jazz, some Kentucky bourbon and a change of pace. The music was bits of their collection, on tape, played on a portable player. It was a contrast in sound and a hint of future musicales.

Meeting Number 48 - Nov. 7-9, 1975; Bellevue-Stratford Hotel, Philadelphia, PA (Laboratory Diagnosis and Monitoring of Disorders Caused by Drugs and Toxic Agents).

The meeting was formally convened on November 7th by greetings from the President of the Association, Dr. M. Michael Lubran, and the Director of Education, Dr. F. William Sunderman. Two hundred fifty-two clinical scientists were in attendance. The scientific sessions were devoted to "The Laboratory Diagnosis and Monitoring of Disorders Caused by Drugs and Toxic Agents". As usual, the scientific presentations were both excellent and comprehensive, including 75 scientific papers and 24 demonstrations of methodology.

On Friday evening, November 7th, the Annual Banquet was held at the Bellevue-Stratford Hotel, attended by 142 clinical scientists and guests. A Diploma of Honor was presented to Irene E. Roeckel, M.D., in recognition of her outstanding contributions to laboratory medicine, and her manifold services to the Association. The Sunderman Award of a silver goblet and designation as "Clinical Scientist of the Year" was presented to Howard Quittner, M.D., in recognition of his important achievements in the laboratory diagnosis of diseases and his dynamic leadership. Dr. Quittner responded with a delightful address entitled "Spirits of '76 - A New Vintage?"

President Lubran, Toastmaster of the Annual Banquet, gave special recognition to Dr. Claude E. Brown, who had just celebrated his one hundredth birthday. Dr. Brown was present at the banquet, and he was honored by a standing ovation which expressed the affection and esteem of all of the members of the Association.

The Banquet Address was presented by John F. Kincaid, Ph.D.  Dr. Kincaid's topic was "The Pace of Change". In a brilliant and penetrating discourse, Dr. Kincaid traced the major technological developments in the history of man and he considered the factors that were responsible for acceleration of technological advances during recent generations. 

On Saturday evening, a program of popular music was held with commentary by Mel A. Davis, M.D., and following this entertaining session, chamber music was presented by members of the Association and participants in the Seminar.

This was the last meeting to be held at the prestigious Bellevue-Stratford Hotel which was to close after the outbreak of Legionnaire’s Disease in 1976.

The Association of Clinical Scientists - 1976

Meeting Number 49. - April 21-25, 1976; Hyatt Hotel; University of Puerto Rico Medical School; San Juan, PR

Meeting Number 50. - Nov 5-7, 1976; Shoreham Hotel; Washington, DC (Clinical Enzymology)

President - John Savory PhD

Vice-President - Henry A Teloh MD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR F William Sunderman Jr MD

DIPLOMA OF HONOR Elgin P Kintner MD

ABRAHAM J GITLITZ MEMORIAL LECTURESHIP Ramon M Suarez MD "Aging."

Meeting Number 49. - April 21-25. 1976; Hyatt Hotel; University of Puerto Rico Medical School; San Juan, PR.

The Spring Meeting of the Association of Clinical Scientists took place in San Juan, Puerto Rico on April 22 to 25, 1976. The program Chairman was Dr. Oscar G. Costa Mandry. On Thursday, April 22nd, a symposium on "Perspectives on Medical Care and Public Health in Puerto Rico" was held at the Hyatt Hotel under the chairmanship of Dr. Augustin Cajigas. The program included presentations by several prominent clinical scientists and health administrators in Puerto Rico. The highpoint of this meeting was the Abraham J. Gitlitz Memorial Lecture on "Aging" which was presented by Dr. Ramon M. Suarez, a distinguished clinician who has made notable observations in the subject of geriatrics.

On Friday, April 23rd, scientific sessions were held all day in the Clinical Amphitheater of the University of Puerto Rico School of Medicine, and included excellent presentations by numerous members of the medical faculty. On Saturday, April 24th, scientific sessions were held at the Hyatt Hotel, and included scientific papers by members and guests of the Association of Clinical Scientists. A total of sixty-four scientific papers were included in the three-day program. In addition to numerous local scientists, there were 109 clinical scientists who registered for the meeting.

On Friday evening, April 23rd, the Association Banquet was held at the Hyatt Hotel, attended by 129 clinical scientists and guests. The Toastmaster was Dr. John Savory. President of the Association of Clinical Scientists. The Banquet Address was presented by Dr. Jorge Fernandez Pabon, Chancellor of the Medical Sciences Campus of the University of Puerto Rico. Dr. Pabon's address was enthusiastically received, and was followed by delightful folk dancing by the Areyto Dancers of Puerto Rico.

On Saturday evening, April 24th, Dr. F. William Sunderman presented an illustrated lecture on his recent expedition to Antarctica. This delightful lecture was followed by a program of chamber music, highlighted by vocal selections by Dr. Janis Klavins, accompanied by Mrs. Ellen Wen (piano), Dr. F. William Sunderman (violin) and Dr. F. William Sunderman, Jr. (viola).

Meeting Number 50. - Nov. 5-7, 1976; Shoreham Hotel; Washington, DC Clinical Enzymology)

The Annual Applied Seminar of the Association of Clinical Scientists was held at the Shoreham-Americana Hotel on November 5 to 7, 1976.  The meeting was formally convened on November 5th by greetings from the President of the Association, Dr. John Savory, and the Director of Education, Dr. F. William Sunderman. Three hundred clinical scientists were in attendance. The scientific sessions were devoted to  "Clinical Enzymology". As usual, the scientific presentations were both excellent and comprehensive, including 60 scientific papers and 18 demonstrations of methodology.

On Friday evening, November 5th, the Annual Banquet was held at the Shoreham-Americana Hotel, attended by 150 clinical scientists and guest. A Diploma of Honor was presented to Elgin P. Kintner, M.D., in recognition of his outstanding contributions to laboratory medicine, and his manifold services to the Association. The Sunderman Award of a silver goblet and designation as "Clinical Scientist of the Year" was presented to F. William Sunderman, Jr.  Dr. Sunderman responded with an address entitled "Perspectives on Legionnaire's Disease".

The Banquet Address was presented by Guy G. Guthridge, Head of the Polar Information Service, National Science Foundation, on the topic "Antarctica".  Dr. Guthridge's interesting address was illustrated by many beautiful color slides. On Saturday evening, a musical performance: of Chamber music was presented by members of the Association and participants in the Seminar.

The Association of Clinical Scientists - 1977

Meeting Number 51. - March 2-5, 1977; Congress Centre, Monte Carlo, Monaco (International Symposium on Clinical Chemistry and Chemical Toxicology of Metals)

Meeting Number 52. - April 28-May 1, 1977; Christopher Inn; Battelle Columbus Laboratories; Ohio State University School of Medicine; Columbus, OH

President – Henry A. Teloh MD; Vice-President – Bernard Gondos MD; Secretary-Treasurer F. William Sunderman Jr MD CLINICAL SCIENTIST OF THE YEAR John Savory PhD DIPLOMA OF HONOR Donald T. Forman PhD CLAUDE P. BROWN MEMORIAL Lectureship F. William Sunderman MD PhD “The Perils of Mercury”.

Upon invitation by Dr. Mel A. Davis, the Spring meeting of the Association was held in Columbus, Ohio.  This was appropriate, as by this time, the membership included many from the Midwest.  An outstanding group forming the program committee were leading scientists and clinicians at Ohio State University.  The program committee included Dr. Herbert Derman who moved from New York to Ohio and Drs. Brooks H. Heard, Robert C. Hersh and George W. Smithers who organized a brilliant program.  This included tours and scientific presentations at Battelle Columbus Laboratories and at the Ohio State University School of Medicine.

On Friday, the Battelle biomedical research team presented ten lectures on their current scientific projects ranging from the development of animal models for experimental treatment of human tumor transplants to implantable material.  This contributor was much impressed by the ceramic tooth implants in baboons.

Tours of Battelle’s facilities in the afternoon included presentations of biomedical applications of computers, projects of the bioengineering laboratory and gas chromatography/mass spectroscopy in the quantitation of drugs in body fluids.  Concluding the afternoon program, two historical lectures were presented.  The Claude B. Brown Memorial Lecture by F. W. Sunderman, Sr., M.D., Ph.D., “The Perils of Mercury” and by Dr. Harold Mulkin:  “The Influence of William Osler on the Development of Clinical Laboratory Medicine”.  Dr. Mulkin’s presentation was published in the Annals (Ann Clin Lab Sci 1977; 7:281).

The scientific session on Saturday started with papers from Ohio State University describing various research results of members of the Faculty followed by 26 papers by members of the Association, the last five on Sunday morning.  All reports were published in the abstracts and several resulted in full communications in the Annals.

The highlights of the social agenda included the Association banquet on Friday, the 27th featuring “Some Reflections on Analytical Instrumentation” by Dr. Arnold O. Beckman, founder and chairman of Beckman Instruments, Inc. of Irvine, California.

There was a full program organized by the auxiliary to the Association for ladies and guests with tours to the Ohio Theatre, to the German Village and of course participation in the Friday banquet and the Saturday evening dinner and musicale.

Some curiosities and fond memories are recalled by Zimmie Davis as follows.  “Remember that town that had the pie-shaped hotel rooms and the meetings at the Center of Science and Industry? Martha-Lee was attacked with paper airplanes by small visitors to the Center. No damage sustained.”

An unexpected treat was hearing the history of Beckman Instruments by Dr. Beckman. Hearing the progress of laboratory methods and equipment, in such a short span of time, from a man who was a pioneer in the field made it a special banquet. 

From Battelle Institute to Ohio State University with the help of Jean and Brooks Hurd, Clare and Bob Harsh, George Smetters, Herb and Trude Derman, Ludolph and Francine vanderHoeven, Columbus gave its welcome to the Association. (Zimmie Davis)

Meeting Number 53. – Nov ll-13, 1977; Drake Hotel, Northwestern University Medical School; Chicago, IL;  (Proteins and Proteinopathies)

The Seminar held at the Drake Hotel in Chicago, Illinois had some nostalgic effect on the founding members of the association recalling the early meetings of the Clinical Science Club at this hotel.  The subject, Proteins and Proteinopathies, was reviewed in great detail during 11 sessions spread through three days from Friday to Sunday inclusive.  Fundamental considerations, measurements of proteins and demonstration methodologies and clinical interpretations were presented by a galaxy of scientists and clinicians.  At the annual banquet on Friday, the 11th, President Henry A. Teloh, M.D. made the presentation of the Diploma of Honor to Dr. Donald T. Forman and of the Sunderman Award to Clinical Scientist of the Year to Dr. John Savory.  Dr. Savory acknowledged the prestigious award by his response “A Comedy of Errors”.

The banquet address was by founding member, one of the original group from Chicago, Dr. George F. Stevenson.  His address was entitled “Continuing Medical Education, Little Red Riding Hood and the Wolf”.  Dr. Stevenson, at the time Scientific Director of the ASCP, brought the experience gained in the Association’s seminars to bear on the educational programs of the ASCP including the workshop concepts.  His address was warmly applauded by members and guests attending the Association banquet.

Saturday evening, there was a musical performance by members of the Association and participants of the Seminar.

The auxiliary arranged a delightful program for guests with tours of the Oriental Institute of Art, of the University of Chicago Campus including the Rockefeller Chapel with its gothic architecture and of the Art Institute of Chicago.  Free time was allotted for shopping on State Street or on Michigan Avenue.

At the Executive Committee Meeting, a day before the seminar, Dr. Robert MacFate was reported to be unavoidably absent.  His usual solid scientific contributions and his cheerful joviality was much missed by all of the participants, particularly in Chicago, his homegrounds.  The total membership in the secretary’s report was 691.

There was enthusiastic support for the Association’s participation in the Intersociety Pathology Council programs, Dr. Sunderman, Sr. acting as representative of the Association.

Dr. Teloh reported the activities of an ad hoc committee to review the draft recommendations for the accreditation manual for hospitals by the Joint Commission of Hospital Accreditation.  This was considered an important contribution our Association should make.

The Association of Clinical Scientists - 1978

Meeting Number 54. - May 4-7, 1978; Fairmont Hotel; University of California Medical School; San Francisco, CA.

Meeting Number 55. - May 22-24, 1978; Caledonien Hotel; Falconbridge Nikkelwerk; Kristiansand, Norway (Kristiansand Conference on Nickel Toxicology)

Meeting Number 56. - Nov 3-5, 1978; Shoreham-Americana Hotel, Washington, DC (Clinical Pathology of Cancer of the Endocrine Glands and Target Organs)

President - Bernard Gondos MD

Vice-President - Edward E Morse MD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Owen M Rennert MD

DIPLOMA OF HONOR Albert Cannon MD

ABRAHAM J GITLITZ MEMORIAL LECTURESHIP Thomas Hayes MD "Discovery and Proof: The Role of Intuition and Logic in Electron Microscopy."

Meeting Number 54. - May 4-7, 1978; Fairmont Hotel; University of California Medical School; San Francisco, CA.

The Spring meeting of the Association was convened in San Francisco, California upon invitation of Dr. Bernard Gondos, Association President.  There were elaborate preparations to bring the Association to the West Coast.  There were 37 scientific papers presented, many by faculty members of the University of California in San Francisco.  The theme of aspiration cytology was extensively discussed, both from a diagnostic and from an investigational standpoint.  Several papers included ultrastructural studies of cytologic specimens and particularly cell surface scanning by SEM and its value both in education and occasionally in diagnosis.

The staff of Harbor Hospital was well represented from Torrance, California, the home base of our past president, Michael Lubran, M.D.  The scientific program was strongly supported by contributions from the membership from the University of Connecticut, from the University of Chicago and from the Medical University of South Carolina.

For the members and guests, particularly from the East Coast, Dr. Gondos arranged a scenic tour of Napa Valley and two wineries.  In the evening, on Friday, a reception and banquet was held at the Fairmont Hotel.

On Saturday, May 6, lectures and tours were held at the University of California School of Medicine.  The Abraham J. Gitlitz Lecture was delivered by Dr. Thomas Hayes on “Discovery of Proof:  The Role of Intuition and Logic in Electron Microscopy”.  The auxiliary had an enjoyable visit to San Francisco, snapshot-like memories are recorded by Zimmie Davis:  “Women on cable cars, bargaining in china Town, shopping on the wharf, to lunch in Saulsalito, gave the Auxiliary a view of San Francisco with a different life-style. 

Meeting Number 55. - May 22-24, 1978; Caledonien Hotel; Falconbridge Nikkelwerk; Kristiansand, Norway (Kristiansand Conference on Nickel Toxicology)

The Kristiansand Conference on Nickel Toxicology was jointly organized by the Association of Clinical Scientists and the International Union for Pure and Applied Chemistry.  Dr. F. William Sunderman, Jr. chaired the meeting with scientific sessions on Methods of Nickel Analysis, Monitoring Industrial Exposures to Nickel, Experimental Studies of Nickel Metabolism and Toxicology.

Meeting Number 56. - Nov. 3-5, 1978; Shoreham-Americana Hotel, Washington, DC (Clinical Pathology of Cancer of the Endocrine Glands and Target Organs)

Three full days were dedicated to a comprehensive review of the subject with fundamental considerations, demonstrations in methodologies and clinical interpretation of all of the endocrine organs.  In addition, original studies were presented and the faculty included many revered leaders in clinical science.  Chairing the local arrangements was Dr. Vernon E. Martens.  The music committee was chaired by Ludolph H. Van der Hoeven, M.D. and J. V. Klavins, M.D., Ph.D.  The auxiliary program was organized by Mrs. Vernon E. Martens, Mrs. Mel A. Davis and Mrs. Frank T. Hamilton.

During the annual banquet on Friday, November 3, 1978, President of the Association, Dr. Bernard Gondos gave the presentations, the Diploma of Honor to Albert Cannon, M.D. and the Sunderman Award to the Clinical Scientist for 1978 to Dr. Owen M. Rennert.  Dr. Rennert’s response titled:  “Man, the Unknown” was well received.

The banquet address was given by John Z. Bowers, M.D., President, Josiah Massey, Jr. Foundation, New York, NY.  National President, Alpha Omega Alpha, Honor Medical Society.  His title:  “The Odyssey of Western Medicine to the Orient”.

Saturday evening, the musicale was preceded by a memorial tribute to Dr. Robert P. MacFate.  Dr. MacFate died October 3, 1978, just one month before the seminar meeting.  The members paid valediction to a beloved friend, an eminent clinical scientist, a renowned teacher, a founding member of our Association of Clinical Scientists, and Secretary-Treasurer for the first twenty years of the Association’s existence.  F. William Sunderman, Sr. narrated the memorial tribute and Dr. Mel A. Davis recited an appropriate poem on the occasion.  The full text is reproduced in the Annals of Clinical and Laboratory Science, 1979; 9:85.

The Clinical Scientists string quartet played the Andante Cantabile movement from the first quartet of Tschaikovsky’s opus 11, after which the audience stood for a moment of silence.

The program of the auxiliary was equally busy and outstanding as the scientific programs.  The auxiliary tours included a special tour of the Lighthouse, the FBI building and the National Cathedral, still under construction at that time.

The Association of Clinical Scientists – 1979

Meeting Number 57. - May 3-6, 1979; Mills-Hyatt House; Medical University of South Carolina; Charleston, SC

Meeting Number 58. - Oct. 11-14, 1979; Ben Franklin Hotel; Jefferson Medical College; Philadelphia, PA (Biochemical Hematology)

President - Edward E Morse MD

Vice-President - John V Klavins MD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Elgin A Cowart Jr MD

DIPLOMA OF HONOR Henry A Teloh MD

CLAUDE P BROWN MEMORIAL LECTURESHIP Robert M Galbraith MD "Recent Advances in Immunology."

Meeting Number 57. - May 3-6, 1979; Mills-Hyatt House; Medical University of South Carolina; Charleston, SC

Recent Advances in Clinical Science was the title of the Spring meeting held in Charleston, SC on invitation extended by Drs. Albert Cannon and Richard Gadsden who co-chaired the program committee.

On Thursday, May 3, a tour of “Science and History of the South Carolina Low Country” with stops and informative presentations included the “South Carolina Marine Resources Laboratory”, Drayton Hall as an example of Georgian plantation architecture, and Middleton Place, its plantation house, stables and gardens.  After luncheon at Raybestos-Manhattan Plant, Dr. H. C. Lewinsohn spoke on the surveillance and environmental monitoring program for asbestos workers.

Friday through Sunday in eight scientific sessions, 40 papers were presented including the latest information available in a variety of fields of clinical science.  The Claude C. Brown Memorial Lecture entitled “Recent Advances in Immunology” was delivered by Robert M. Galbraith of Charleston, SC.  Edward E. Morse, Association President, served as toast master at the Association banquet on Friday evening.

Saturday evening, May 5, a musicale arranged by Ludolph van der Hoeven consisted of vocal and instrumental chamber music in commemoration of the 150th anniversary of the death of Franz Schubert.  John V. Klavins was singing Schubert’s lieders and F. W. Sunderman, Sr. delivered the commemorative remarks:  “Schubert’s seraphic experience”.  The meeting was a great success and much credit was due to the local organizing committee and Armand Glassman, Chair, Department of Pathology of Medical University of South Carolina.

Association members enjoyed gourmet dining at Mr. Roberts.  As Zimmie Davis remembers, Mr. Roberts was a gourmet chef and opera singer.  She found that food and music do go together.  Being entertained with song by Mr. Roberts between courses, Zimmie was wondering who was in the kitchen.  It was a fun evening.

Meeting Number 58. - Oct. 11-14, 1979; Ben Franklin Hotel; Jefferson Medical College; Philadelphia, PA (Biochemical Hematology)

Upon invitation by Dr. F. W. Sunderman, Sr., the applied seminar on biochemical hematology was held in Philadelphia, PA on October 12, 13 and 14, 1979.  This was a festive meeting celebrating 25 years of applied seminars.  On this 25th annual seminar, the topic selected was the same as for the first one.  Much advancement in the field occurred during the quarter century since the 1954 first applied seminar on hemoglobinometry.

A faculty of 81 clinical scientists, many recognized authorities in the field, presented concise overviews, covering fundamental considerations, interpretations and applications of clinical measurements in clinical medicine.

In numerous demonstrations, the most up-to-date analytical procedures were presented and a manual of recommended procedures was furnished.  To date, this manual is the most extensive compilation of the seminars presented so far.  It is 436 pages and was published for the Association by the Institute for Clinical Science.  The volume was compiled by Dr. F. W. Sunderman, Sr. and it is entitled “Manual of Procedures of the Seminar on Biochemical Hematology, 1979”.

All lectures and laboratory demonstrations were conducted at the Benjamin Franklin Hotel and the seminar was of practical usefulness to internist, pathologists, clinical chemists, and workers in allied medical fields.

The seminar banquet, a Philadelphia Madeira Party, was held at the Union League Club on Friday evening.  Dr. Sunderman, Sr. served as host and toast master.  This was a grand celebration of the Association 25 years progress and exceptional achievements in leadership of F. William Sunderman, Sr. as the Association’s Director of education.  For this memorable event, Dr. Sunderman published a limited edition booklet “Our Madeira Heritage”, a handsome small volume illustrated by the author’s photographs of Madeira, Funchal, wines and scenes of the island.

The terrapin served at the dinner according to historical recipe appeared somewhat exotic to current taste but the dessert including tasting of various vintages of malmsey from Dr. Sunderman’s private collection was an exceptional treat never to be forgotten.  An overview photograph of the banquet records the festive atmosphere with the participants at their tables.

President Edward E. Morse presented the Clinical Scientist of the Year award to Elgin A. Cowart, Jr., M.D. and the Diploma of Honor to Henry A. Teloh, M.D. during the banquet.

The Association of Clinical Scientists – 1980

Meeting Number 59. - May 8-11, 1980; Colonnade Hotel; Harvard Medical School; Boston, MA

Meeting Number 60. - Sept 3-5, 1980; Dragon Hotel; University College of Swansea, Swansea, Wales, United Kingdom; (Swansea Conference on Nickel Toxicology)

Meeting Number 61. - Oct 31-Nov. 2, 1980; Drake Hotel, Chicago, IL (Laboratory Diagnosis and Monitoring of Disorders of the Kidney)

President - John V Klavins MD

Vice-President - Owen M Rennert MD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

GOLD-HEADED CANE AWARD Shields Warren MD

CLINICAL SCIENTIST OF THE YEAR Edward E Morse MD

DIPLOMA OF HONOR Edward E Bermes Jr PhD

ABRAHAM J GITLITZ MEMORIAL LECTURESHIP Owen M Rennert MD "Polyamines in Health and Disease."

Meeting Number 59. - May 8-11, 1980; Colonnade Hotel; Harvard Medical School; Boston, MA

The Spring meeting “Recent Advances in Clinical Science” was held in Boston, MA, May 8-11, 1980.  Dr. Israel Diamond, Chairman of the Program Committee formulated the social and scientific programs.  The first three scientific sessions were held at New England Deaconess Hospital of Harvard Medical School.  The host faculty presented their research results in 14 papers ranging from autopsy studies of renal allografts in diabetic patients to quality control in therapeutic drug monitoring.  During five additional sessions, Association members presented their work in 30 additional papers.

Dr. Owen M. Rennert gave the Abraham Gitlitz Memorial Lecture entitled “Polyamines in Health and Disease”.

All through the scientific sessions, there was a special sentiment imposed by the presence of Dr. Shields Warren, a senior statesman and almost a legendary figure in American pathology.  The Association’s banquet was in recognition of the contributions of Dr. Warren to the science of medicine.  Association President, Dr. John V. Klavins, served as toast master and gave the salutation and introductions.  Tributes were presented by Drs. Merle A. Legg, Chairman, Department of Pathology of New England Deaconess Hospital, by John Z. Bowers, President, Josiah Massey, Jr. Foundation, by F. William Sunderman, Sr., Director of Education of the Association of Clinical Scientists, and Dr. Earl B. Wert, Chairman, Awards Committee, Association of Clinical Scientists.  Dr. Warren was presented with the Association’s Gold-Headed Cane.  Dr. Warren was a distinguished member of the Association of Clinical Scientists; unfortunately 1980 was his last year.  His passing is remembered in the Annals of Clinical and Laboratory Science, Vol. 11:94.  It is fortunate that the membership could enjoy an elegant banquet with Dr. Shields Warren and pay tribute to him for his achievements in pathology and nuclear medicine.

The Executive Committee meeting held May 8, 1980, besides the usual housekeeping problems, discussed future educational meetings, the applied seminars for 1980, 81 and 82.  Future meeting plans for the spring meeting were also decided upon.  For 1981, a spring meeting site of Tampa, FL, for 1982 Los Angeles, CA, and for 1983 Charlottesville, VA was decided upon.  Changes in membership were accounted for, the total membership at this time being 735.  There were 640 active fellows, 54 Emeritus members, 6 junior members, 5 honorary fellows, corresponding and associate members together 28, and inactive fellows 2.

Meeting Number 60. - Sept 3-5, 1980; Dragon Hotel; University College of Swansea. Swansea, Wales, United Kingdom; (Swansea Conference on Nickel Toxicology)

Meeting Number 61. - Oct. 31-Nov. 2, 1980; Drake Hotel, Chicago, IL (Laboratory Diagnosis and Monitoring of Disorders of the Kidney)

The seminar and workshop revisited the subject first presented in 1967 in Washington, DC.

Comprehensive review of new information gained during the 23 year period was presented by a large faculty composed of Association members and guest speakers.  In addition, 18 laboratory procedures were presented and compiled in the manual of procedures for the applied seminar on Laboratory Diagnosis and Monitoring of Disorders of the Kidney.  It is worth quoting from the foreword to this manual by Dr. F. William Sunderman, Sr. as follows:  “Never in the history of civilization has scientific knowledge advanced with the rapidity that it does in our present computer age.  In recent years, one of the most striking changes in clinical science is the accelerated rate of change itself.  The applied seminars of the Association of Clinical Scientists are designed to cope with these changing times so that the dissemination of knowledge in clinical science may keep pace with the acquisitions.

The furtherance of clinical science depends in large measure upon research and development in methodology.  It is for this reason that a number of procedures are presented at the seminar that are not routinely undertaken in many clinical laboratories.  However, in our opinion, these procedures may play increasingly important roles as diagnostic aids in future years.  Detailed descriptions of the procedures are included in this manual.  It is hoped that participants of the seminar will find the manual helpful in establishing the newer methods in their own laboratories.”

Association President, Dr. John V. Klavins, served as toast master of the Association banquet on Friday evening.  The Clinical Scientist of the Year award was presented to Dr. Edward E. Morse, Past President of the Association and long time contributor to the scientific programs and organizer of scientific sections.

The Diploma of Honor was awarded to Dr. Edward E. Bermes, Jr. in recognition of his scientific contributions and multifaceted services to the Association.

The Association of Clinical Scientists – 1981

Meeting Number 62. - May 7-10, 1981; Bay Harbor Inn; St. Joseph's Hospital; University of South Florida College of Medicine; Tampa, FL

Meeting Number 63. - Oct 29-Nov 1, 1981; Barclay Hotel; Philadelphia, PA (Diagnosis of Disorders of the Fetus, Newborn, and Infant)

President - Ludolph H van der Hoeven MD PhD

Vice-President - Richard H Gadsden PhD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Daniel L Weiss MD

DIPLOMA OF HONOR Arthur L Levy PhD

CLAUDE P BROWN MEMORIAL LECTURESHIP Richard F Lockey MD "Advances in Understanding of Allergic Mechanisms."

Points of Interest for #62:  Spring Meeting in Tampa, FL

  1. The first quarterly issue of the Association of Clinical Scientists Newsletter was launched in 1981. (See Vol. 1, No. 1, March, 1981).
  1. The Association, at this point was 31 years old, had received "the unremitting loving guidance from its founder (Dr. Bill Sunderman, Sr.)"
  1. Membership in 1981 was 731, with membership including Ph.D.s, M.D.s and nondoctoral associates. Dr. Bill Sunderman, Sr. stated, "It is unique in that it involves a wide variety of scientific disciplines that are related to the clinical laboratory--chemists, microbiologists, hematologists, industrial researchers, occupational physicians, internists, surgeons, pediatricians, and a host of others."
  1. Regional Coordinators included 11 separate regions of the U.S. and Canada. The first meeting of the newly designated Regional Coordinators was held in Tampa in 1981. Coordinators made suggestions regarding format of seminars, plans for future meetings, membership recruitment, procedures for accepting new members, and awards for scientific presentations.
  1. In 1981 ACS President Ludolph van der Hoeven wrote the following in the first issue of the Newsletter, "Bring spouses and children, learn a lot, and enjoy the beaches. I'll see you in Florida."
  1. The first ACS Newsletter Editor, Bernard Gondos, encouraged all members to keep information coming in for the Newsletter. In Vol. 1, No. 2, June, 1981, he stated that the 1981 Spring Meeting was a great success, and "The organizers, headed by Jeno Szakacs, are to be congratulated for providing superb arrangements."
  1. At this 1981 Spring Meeting the first scientific section meetings dealing with the subjects of Tumor Markers (headed by John Klavins) and Trace Metals (headed by John Savory) were held. John Klavins, the Director of Scientific Sections, "deserves special compliments for getting the sessions off to an excellent start."
  1. Regarding trace metals, three definite projects were established as follows:

(1) Bill Sunderman, Jr., agreed to look into the possibility of using a purified gelatin preparation from Eastman Kodak as a quality assurance material for metals analysis. (2) John Savory aimed another project at gathering information on the repertoire of metal analyses available in Association members' laboratories. In 1981 nickel analysis was available by Bill Sunderman, Jr., manganese by Michael Lubran, and Aluminum in John Savory's laboratory.

(3) Michael Lubran volunteered to write a protocol on the processing of autopsy tissue for trace metal analysis.

  1. A definition of tumor markers arrived at during the 1981 Spring Meeting and later contributions-- "Tumor markers are unique gene products elaborated by tumor cells, excluding substances that occur in excess secondary to the presence of neoplastic disease. Tumor markers are characterized by an abnormal synthesis and release of tumor products."

Regarding tumor markers, participants presented brief summaries of their work as follows:

(1) Hyman Rochman--studied a specific protein produced by prostatic carcinoma and also performed assays for CEA, AFP, and estrogen receptors.

(2) Egil Fosslien--searched for new tumor markers applying Anderson's method of protein separation.

(3) David Bruns--studies amylase activity in ovarian tumors.

(4) Gustavo Reynoso--attempted to characterize a unique protein with a molecular weight of approximately 60,000 daltons produced by malignant neoplasms derived from all three germ layers.

(5) John Savory--studied polyamines in head and neck tumors.

(6) Bill Sunderman, Jr.--investigated the use of ceruloplasmin as a tumor marker.

(7) John Klavins--was involved in studies of possible human embryonic antigen occurring in malignant neoplasms derived from all three germ layers, a pancreatic carcinoma associated antigen, and the relationship of mouse mammary tumor virus and normal human cytotrophoblast.

(8) Through correspondence after the 1981 Spring Meeting, another scientific section was approved on investigation in Occupational Medicine and Pathology (headed by Daniel Weiss).

(9) The third annual ACS Road Race was held on May 10, 1981. "Eleven participants came out at 7:00 a.m. to participate in a 2.5 and 5.0 mile run along the Tampa beach embankment; and, a number of stout-hearted spectators were there at the finish line to cheer the finishers," stated Armand Glassman.

(10) The first organized ACS tennis competition was also held for early risers, Ed Morse, Don Forman, Earl Holmes, and Bernard Gondos, on Sunday morning, May 11, 1981.

Points of Interest for #63:  Fall Seminar in Philadelphia, PA

  1. The registration fee for the Fall 1981 Meeting was $200. And, annual dues for fellows and associates were increased from $35 to $37. Also, the ACS member subscription fee for the Annals of Clinical and Laboratory Science was increased from $35 to $38, according to minutes on file.
  1. Presentations at this meeting were "both excellent and comprehensive, including seventy-six scientific papers and sixteen demonstrations of methods," and "one hundred ninety scientists participated in the meeting".
  1. The Barclay Hotel, around the corner from the famed Curtis Institute of Music, was the site of many special musical treats. At the banquet ACS members listened to Curtis Institute members present musical offerings ranging from Bach to Sondheim, with a liberal sprinkling of Scott Joplin. Also, the musical highlight of our meetings was once again the Saturday evening chamber music performance by members and seminar participants.
  1. Al Free wrote about the Association, "Aspects that particularly appeal to me, in addition to the scholarly, scientific endeavors, are the friendliness, conviviality, culture, and good fellowship that prevail at our two meetings each year--the Spring Meeting and the Fall Seminar."
  1. In Vol. 1, No. 3 (ACS Newsletter), Editor Bernard Gondos stated, "You can have the best of both worlds, by accumulating the necessary (continuing education) credits and having the satisfaction of knowing that you're actually learning something of value in an enjoyable setting among friends and colleagues. See you in Philadelphia!"
  1. Vol. 1, No. 3 listed employment possibilities for faculty positions in blood bank and transfusion service and clinical chemistry and toxicology. Also, an AP/CP Board eligible pathologist listed availability for employment as July, 1982.
  1. News items listed in Vol. 1, No. 3 are indicative of membership activities as follows:
  • F. William Sunderman, Jr.--was presented a plaque for his "outstanding efforts in education and training, in honor of his contribution to obtaining recognition of clinical chemistry as an entity within the discipline of chemistry and his efforts in educating and training clinical chemists." The award was sponsored by Smith Kline Clinical Laboratories.
  • Richard Gadsden--was appointed to the Board of Editors of Clinical Chemistry.
  • Emanuel Mandel--retired as Director of Medicine at Kingsbrook Jewish Medical Center in Brooklyn and was reappointed as physician-in-charge of emergency services.
  • Stanley Burrows--was appointed as Director of the Department of Pathology at Episcopal Hospital in Philadelphia and Clinical Professor of Pathology at Temple University School of Medicine.
  • Agostino Molteni--shared in the Albert E. Lasker Special Award for Public Health given to the Central Laboratory of the Hypertension and Follow-Up Program of the National Heart, Lung and Blood Institute.
  • Stephen Vernon--was appointed Clinical Assistant Professor of Pathology at the University of Miami School of Medicine.
  • F. William Sunderman, Jr.--was elected President of the Clinical Chemistry Division of the International Union of Pure and Applied Chemistry.
  1. ACS Newsletter Editor, Bernard Gondos, stated in the Vol. 1, No. 4 ACS Newsletter that "Music was in the air at the fall seminar in Philadelphia." And, "...particular thanks are in order to Ray Vanderlinde and his Local Arrangements Committee for all of the excellent arrangements."
  1. Regarding scientific sections, the suggestion was made that for Spring Meetings in the future, papers related to the different sections be grouped together to facilitate collaboration among investigators. Highlights regarding sections included:
  • Tumor Markers--participants discussed methods for protein separation, including the TOYO SODA high- performance liquid chromatographic columns, BIORAD PREPARATIVE isoelectric focusing technique, two- dimensional separations by molecular weight and isoelectric focusing, and isotachopheresis. In searching for tumor markers, autoantibody utilization was considered.
  • Occupational Medicine and Pathology--possible future topics for focus: biological monitoring methods for industrial chemicals; methods for analysis and prediction of health hazards in industry; mutagenicity testing and the role of mutagenicity in interpretation of oncogenicity; information needed before analysis of a suspected health hazard; infectious agents associated with occupational problems; methodology for study of complex analytes and their metabolites; extrapolation problems and solutions.
  1. Association of Clinical Scientists 1982 committees are listed as follows: Executive Committee, Credentials Committee, Regional Coordinators, Scientific Council, Constitution and Bylaws Committee, Nominating Committee, Archives Committee, Awards Committee, Publications Committee, Ethics Committee, Committee on Music, Public Relations Committee, Spring Meeting Program Committee, Committee on Athletics, and Auxiliary to the Association.
  1. In the Newsletter ACS President, Ludolph van der Hoeven, thanked the Annals of Clinical and Laboratory Science journal editor-in-chief, F. William Sunderman, Sr., M.D., Ph.D., and Martha-Lee Sunderman and their staff for their work regarding the Tenth Anniversary of the Annals. After this statement, Ludolph completed his year as President of the Association of Clinical Scientists and the leadership passed to Richard Gadsden.

The Association of Clinical Scientists – 1982

Meeting Number 64. - May 6-9, 1982; Sheraton-Miramar Hotel; UCLA Medical School; Beckman Instruments, Inc.; Santa Monica, CA

Meeting Number 65. - June 17-20, 1982; Hotel Vier Jahreszeiten; Munich, Federal Republic of Germany (International Conference on Human Tumor Markers)

Meeting Number 66. - Nov 11-13, 1982; Drake Hotel; Chicago, IL (Laboratory Diagnosis and Monitoring of Cancer)

President - Richard H Gadsden PhD

Vice-President - Daniel L Weiss MD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Bernard Gondos MD

DIPLOMA OF HONOR Arnold O Beckman PhD

ABRAHAM J GITLITZ MEMORIAL LECTURESHIP Paul I Terasaki MD "Monoclonal Antibodies to Tumor Antigens."

Points of Interest for #64:  Spring Meeting in Santa Monica, CA

  1. ACS Editor Bernard Gondos wrote in Vol. 2, No. 1 the following: "...It may well be that 'east is east' and 'west is west,' but I conclude that experiences in running a laboratory are much the same, regardless of location." His statement continued, "...it is desirable to hold meetings in different regions, as has been the custom with the spring meetings for many years. When the meeting happens to take place in southern California, as it does this year, not only is this objective achieved, but we have the opportunity to enjoy a delightful oceanside location. So, take advantage of this opportunity, and we'll see you there!
  1. ACS President, Richard Gadsden stated, "Arrangements for the scientific sessions and social events were extremely well done and we owe special appreciation to Mike Lubran and Avril (Lubran) for their efforts."
  2. During 1982, the Association of Clinical Scientists began to receive voluntary contributions from members. "Contributing Members" donated $100, "Sustaining Members" donated $250, and "Benefactors" donated $1,000.
  1. In Vol. 2, No. 2 (ACS Newsletter), Editor Bernard Gondos stated the following three main advantages for joining the Association of Clinical Scientists as follows:

(1) Promote education in clinical science. "Our educational activities are conducted in a manner that is truly conducive to learning, satisfies continuing education requirements, and enables the acquisition and retention of new information in an enjoyable, relaxed manner. This is quite in contrast to much larger organizations with their overpriced, overorganized, impersonal workshops and seminars. Our fall meeting geared to a particular subject and our spring meeting covering various aspects of laboratory science provide an excellent, pleasurable way to keep up with the latest developments in clinical and laboratory science."

(2) Research.

"While there may not be all that much interest in basic research among recent graduates, many have an interest in presenting papers at meetings, describing their findings based on clinical observations, and submitting manuscripts for publication. Our organization, through the format of its meetings and the Annals, provides an excellent opportunity for such activities. This should be quite appealing to younger individuals confronted with the preparation of abstracts for large, diffuse meetings and submission of manuscripts to journals with prolonged review processes, unsympathetic reviewers, and long publication delays. A distinct advantage of the Association is that the active members get to know one another and develop an appreciation for each other's work, thereby encouraging presentation of new information at meetings and in the Annals."

(3) Collegiality and cooperative spirit. "This should be a special attraction for those who wish to make contacts, establish their credentials, and maintain valuable professional associations. For the young laboratory scientist embarking on a career, these factors may be of considerable importance. Our meetings are particularly well adapted to informal discussions and making acquaintances that could lead to professional advancement. And if there are additional talents in chamber music, choral performance, or jogging, then the possibilities are endless."

(Note: The constitutional objectives of the Association of Clinical scientists are: (a) To promote education and research in clinical science; (b) To improve the accuracy of measurements in clinical laboratories; and (c) To encourage cooperation between physicians and members of other professions concerned with the application of scientific methods to medical practice.)

  1. President, Richard Gadsden, reported that registration for the 1982 Spring Meeting was well over 100. And, members of the Association were guests of Beckman Instruments in Brea for a visit to their facilities and for dinner.
  1. Minutes indicate the highpoint of the scientific sessions was the Abraham J. Gitlitz Memorial Lecture on "Monoclonal Antibodies to Tumor Antigens," by Dr. Paul I. Terasaki of UCLA Medical School.
  1. Dr. Byron A. Myhre, Professor of Pathology at Harbor-UCLA Medical Center and Past President of AABB, gave an address on "Dracula" at the 1982 Spring banquet and presented trumpet and fuglehorn solos during the Association Musicale.
  2. In Santa Monica, the Choral Group, organized by Dr. Edward E. Morse, performed for the first time.
  1. Beckman Instruments provided a guided tour to ACS member and family who went to Disneyland.
  1. A new scientific section on Laboratory Medicine in the Community Hospital was proposed by Fred Muschenheim.
  1. Vol. 2, No. 2 (ACS Newsletter) included the following: Editor's Column, Voluntary Contributions, President's Message, Musical Notes, Annual Road Race, and News Items.

*1982 Meeting #65 June 17-20, 1982; Hotel Vier Jahreszeiten, Munich, Federal Republic of Germany

(International Conference on Human Tumor Markers)

Points of Interest for #65:

  1. This International Conference on Human Tumor Markers (Biological Basis and Clinical Relevance) was sponsored by the European Association for Cancer Research and Co- sponsored by the Association of Clinical Scientists (USA).
  1. Cancer scientists and clinical oncologists from 17 countries came together in order to evaluate the biological basis and the clinical relevance of tumor markers.

Points of Interest for #66:  Fall Seminar in Chicago, IL (Diagnosing and Monitoring of Cancer)

  1. Vol. 2, No. 3 (ACS September, 1982 Newsletter) included the following comments from Daniel Weiss: "Having recently been inundated by technical and interpretive information on the use of chromosome analysis, it occurred to me that everyone in medical laboratories should be aware of the possibilities and the problems of the technology. Karyotyping for number and gross abnormalities of chromosomes gained special prominence with the associations of trisomy 21 with Down's syndrome and the Philadelphia chromosome with chronic myelogenous leukemia. The evolution of new sophisticated techniques, such as banding, has allowed even more discrete observations of malformed chromosomes, such as sister chromatid exchanges, incidentally also providing the cytogeneticist with a tool to classify chromosomes by specific number rather than by groups."

"The results of this development are far-reaching. A good example is the observation that dicentric chromosome formation can be used as a biologic dosimeter for whole-body ionizing radiation. In other words, a study of peripheral blood lymphocytes under strictly controlled conditions can be used as a radiation dosimeter in much the same way as we use the less expensive film badges and thermoluminescent physical dosimeters. A variety of other chromosomal abnormalities has been seen in people who work with chemicals such as ethylene oxide and benzene."

"Since we know that exposure to chemical and physical agents such as these can result in a variety of ill- health outcomes, such as the delayed development of malignancies, can we use the observation of chromosomal abnormality as a predictor of future risk of disease? The question is even more attractive if you concede that cell transformation to a malignant clone is driven by an abnormal organization of the chromosome. Furthermore, studies of chromosomes of cells from human tumors show a wide catalog of abnormalities.”

"The best judgment, at the moment, seems to be that specific chromosomal abnormalities may be related to future risks in general population studies, but probably not in the individual case. The statistical variations among individuals (associated with background rates, wide confidence limit in individual measurements, expression, etc.) are too large to be particularly helpful when one sees a few extra dicentrics or other specific abnormalities. However, if a large enough population is studied and compared with suitable controls, a risk estimate for the group can be calculated with reasonable confidence."

"This field of laboratory investigation undergoing rapid development should be monitored with a clear understanding of its value and its limitations."  The Treasurer reported that the Executive Committee recommended that annual dues for all Fellows and Associates be increased from $37 to $40, and that the member's subscription for the Annals of Clinical and Laboratory Science be increased from $38 to $40.

With 150 scientists and guests in attendance at the November 11 Annual Banquet, The Sunderman Award of a Silver Goblet to the "Clinical Scientist of the Year" was presented to Bernard Gondos, M.D., in recognition of his scientific accomplishments and professional leadership. Dr. Gondos responded with a stimulating address entitled "The Language of Science."

The Association of Clinical Scientists – 1983

Meeting Number 67. - May 12-15, 1983; Boar's Head Inn; University of Virginia Medical Center; Charlottesville, VA

Meeting Number 68. - July 19-22, 1983; Sheraton Centre; Montreal, Canada (Second International Conference on Clinical Chemistry and Chemical Toxicology of Metals)

Meeting Number 69. - Nov 10-13, 1983; Shoreham Hotel; Washington, DC; (Clinical Pathology of Liver and Biliary Tract)

President - Daniel L Weiss MD

Vice-President - Kendall Kane MD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR John Klavins MD

DIPLOMA OF HONOR Harry F Weisberg MD

YOUNG CLINICAL SCIENTIST AWARD Petrina V Genco PhD

CLAUDE P BROWN MEMORIAL LECTURESHIP Joseph Larner MD PhD "Cell Membrane Signals in the Mechanism of Insulin Action."

Points of Interest for #67:  Spring Meeting, Charlottesville, VA

ACS Newsletter Editor, Bernard Gondos, stated in the Vol. 3, No. 2 ACS Newsletter that "Scientific, cultural and social events all conveyed a level of excellence and enthusiasm in which members and guests could take special pride." And, "Particular appreciation were expressed to John Savory and Michael Wills along with their committee for the outstanding local arrangements."

On Friday, 13 May, scientific sessions were held at the University of Virginia School of Medicine, opening with the Claude P. Brown Lecture on "Cell Membrane Signals in the Mechanism of Insulin Action" by Dr. Joseph Larner, Professor of Pharmacology at the University of Virginia.

At the 1983 Spring Meeting, Dr. Kenneth Crispell, Dean Emeritus of the University of Virginia Medical School, spoke at the banquet in the magnificent University of Virginia Rotunda (designed by Thomas Jefferson). ACS attendees listened to Dr. Crispell's words which described Jefferson's prescient views on medical education. His address was entitled, "Jefferson and Flexner - Medical Education Revisited."

On Saturday evening, 14 May, a Musicale was organized by Dr. Ludolph van der Hoeven in commemoration of the 150th anniversary of the birth of Johannes Brahms. The program opened with a memorable address by Dr. F. William Sunderman, Sr. on the friendship between Johannes Brahms and Theodore Billroth, Professor of Surgery at the University of Vienna.

Through Bill Sunderman, Sr.'s efforts, the Accreditation Council for Continuing Medical Education approved reaccreditation of the Association of Clinical Scientists for the next six years.

The Accreditation Review Committee made the following comment with respect to ACS's continuing education program: "This association is an exemplar of a 'learned' society fulfilling all of the essentials and serving the needs of its members."

Points of Interest for #69:  Seminar Meeting in Washington, DC (Clinical Pathology of Liver and Biliary Tract)

1983 was the first year the Young Clinical Scientist Award was presented. The initial recipient was Petrina Genco. Vol. 3, No. 4 (ACS Newsletter) included the following: Editor's Column, Young Clinical Scientist Award, Scientific Definitions, Bermuda Trip, Voluntary Contributors, and News Items.

The Treasurer reported the Executive Committee's recommendation that the 1984 annual dues for Fellows and associates be increased by $5 to $45, and that the subscription fee for the Annals of Clinical and Laboratory Science be increased by $5 to $45.

Several of Dan Weiss' favorites regarding touring Washington in Vol. 4, No.1 (ACS Newsletter) are listed as follows:

(1) "The Library of Congress on Capitol Hill, next to the Supreme Court Building, houses a fabulous music collection..."

(2) "Next to the Library of Congress stands the Folger Library, with one of the great Shakespearean collections of the modern world..."

(3) "My personal choice for the best of Washington is Dunbarton Oaks, just above Georgetown. Once a luxurious residence, it is now a museum of Byzantine art, with a small added building housing a very nice Mexican and South American Collection. But the prize of Dunbarton is the garden, as richly designed and displayed as any garden estate I have ever seen, and a delightful place for a picnic on a sunny day."

The Association of Clinical Scientists - 1984

Meeting Number 70. - Feb 20-22, 1984; Hilton Hotel; Vienna, Austria (Second International Congress on Human Tumor Markers)

Meeting Number 71. - May 3-6, 1984; Hilton Hotel; University of South Alabama Medical School; Mobile, AL

Meeting Number 72. - Sept 4-7, 1984; PLM-St Jacques Hotel, Société Le Nickel; Paris, France; (Paris Conference on Nickel Metabolism and Toxicology)

Meeting Number 73. - Nov 15-18, 1984; Barclay Hotel, Philadelphia, PA (Clinical Pathology of Reproductive Systems)

President - Kendall Kane MD

Vice-President - Egil Fosslien MD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

GOLD-HEADED CANE AWARD Oscar G Costa Mandry MD

CLINICAL SCIENTIST OF THE YEAR Richard H Gadsden Sr PhD

DIPLOMA OF HONOR Paul C Fu PhD

YOUNG CLINICAL SCIENTIST AWARD Sidney M Hopfer PhD

ABRAHAM J GITLITZ MEMORIAL LECTURESHIP Joseph H Coggins PhD"Advances in Understanding Cancer Induction: Clues for Cancer Diagnosis and Typing."

Points of Interest for #70:

The Vienna meeting was sponsored by the International Society of Preventive Oncology and co-sponsored by the Association of Clinical Scientists and the Austrian Cancer Society.

Points of Interest for #71:  Spring Meeting in Mobile, AL

In commemoration of the Thirty-Fifth Anniversary of the Association, a program on the History and Evolution of Clinical Hemoglobinometry was organized by Dr. Earl B. Wert and Dr. F. William Sunderman, Sr.

A field trip to the Bermuda Biological Station was attended by 30 people during May 23-30, 1984.  The Abraham J. Gitlitz Memorial Lecture, entitled "Rapid Advances in Understanding Cancer Induction: Clues for Future Cancer Diagnosis and Typing," was presented by Dr. Joseph H. Coggins, Professor of Microbiology at the University of South Alabama.

A new scientific section on Immunohematology, under the leadership of Dr. Edward Morse, was approved. "This will enable clinical scientists with interest in red cell, leukocyte or platelet antigens, histocompatibility, cellular and serologic immunology, blood cell metabolism, artificial blood or infectious complication of blood transfusion to exchange ideas, visit each other's laboratories, present papers on recent advances at our meetings, and publish their reviews or original observations in the Annals of clinical and Laboratory Science."

Vol. 4, No. 2 (ACS Newsletter) included the following: Editor's Column, News Items, Meeting on Nickel Metabolism and toxicology in Paris, Voluntary Contributors, Special Discounts, and Scientific Sections.

Meeting #72 Sept 4-7, 1984; PLM St. Jacques Hotel Societe Le Nickel, Paris, France (Paris Conference on Nickel Metabolism and Toxicology)

Hypernickelemia in hemodialysis patients and in patients with severe angina pectoris were among the exciting 1984 advances that were presented at the Third International Conference on Nickel Metabolism and Toxicology in Paris.

Points of Interest for #73:  Seminar in Philadelphia, PA (Clinical Pathology of Reproductive Systems)

Eastern Airlines offered ACS members a 30% discount on airfare to Philadelphia for the 1984 Fall meeting.

One hundred seventy-seven scientists registered for the 1984 Spring Meeting.

Topics discussed include the following: Anatomic and Physiologic Considerations, Genetics and Teratology, Fertility, Estrogens and Androgens, Gonadotrophins, Hormones and Enzymes, Steroids, Pregnancy and Associated Tests, Infections and Diseases, Immunology, Cytology, Hematology in Reproduction, Malignancies and Associated Lesions, Therapy and Toxicology, Miscellaneous, and Demonstrations and Methodology in Manual.

Vol. 4, No. 3 (ACS Newsletter) included a description of the scientific and musical activities of Bill Sunderman, Sr., (taken from an article in the Hahnemann University Bulletin):

"An accomplished violinist, F. William Sunderman, M.D., Ph.D., Professor of Pathology and Director, Institute for Clinical science, has traveled to more than 175 countries to make scientific presentations. On those journeys he always carries at least one violin and a directory that lists musicians worldwide who play chamber music."

"No matter where Dr. Sunderman travels, be it, as in recent years, to the deserts and mountains of North and South Yemen, the Galapagos Islands and even the Antarctic, he makes time to practice 'every day for an hour,' he said, 'religiously.' Dr. Sunderman recalls one practice session in Antarctica that attracted a group of penguins, prompting one colleague to comment that his audience was, at least, properly attired."

"Music and medicine have always been entwined in Dr. Sunderman's life. 'I put myself through college and medical school by playing the violin,' he said. 'I used to play "big band" music when I was in college, and I played in a piano trio on Sunday afternoons at the old Bellevue Hotel.'"

"At home in Philadelphia, Dr. Sunderman often plays chamber music with amateur and professional musicians. He is particularly proud of a music room in his center city home that has excellent acoustics."

"As devoted as he is to his music, he is still first and foremost a physician. A pioneer in the field of electrolyte metabolism, Dr. Sunderman is a leader in proficiency testing for clinical laboratories and a strong supporter of continuing education for physicians. He has served on the faculties of four of Philadelphia's five medical schools as well as at Emory University, the University of Texas, and the Cleveland Clinic."

"Dr. Sunderman is cited in 'Who's Who in the World,' 'Who's Who in America' and 'American Men in Science' and 'International Who's Who in Music.' He has written more than 300 scientific articles and has edited 14 medical books. He recently wrote a book entitled 'Musical Notes of a Physician.'"

"Next on Dr. Sunderman's scientific agenda are Czechoslovakia and France. There he will share his knowledge and his art with friends and colleagues from across the sea."

(Note: In 1984, Dr. F. William "Bill" Sunderman, Sr., was 85 years old.)

The Association's Annual Banquet, held at the Union League Club on Thursday evening, 15 November, was a Madeira Party in celebration of the association's 35th Anniversary, attended by 187 scientists and guests.

The Sunderman Award of a Silver Goblet to the "Clinical Scientist of the Year" was presented to Richard H. Gadsden, Ph.D., in the field of clinical biochemistry.

The gold-headed cane was awarded to Dr. Oscar Costa Mandry, founding fellow of the Association and the most gracious host of our 1976 Spring Meeting in San Juan.  As the top public health officer of the Commonwealth of Puerto Rico, Dr. Costa Mandry contributed much to control tropical diseases on his Island.  He was one of the early members of the Clinical Science Club and a solid supporter of the Association of Clinical Scientists.

President Kane then recognized Dr. Paul C. Fu for his contributions to clinical chemistry and his valued participation on the faculty of the Association’s workshops with the Diploma of Honor.

This was the second time that the Young Clinical Scientist award was given in recognition of efforts by young scientists and to encourage their scholarly activities.  The 1984 Young Clinical Scientist award was well merited by Sidney M. Hopfer who, besides his excellent scientific contributions, made valuable efforts to attract younger investigators to the Association.

The Madeira Ceremony, an old Philadelphia custom, was conducted by F. William Sunderman, Sr., M.D., including tasting of several fine vintages of Madeira, including one bottle of the 1826 vintage.

On Saturday evening, 17 November, a program of chamber music was presented by members of the Association, under the direction of Dr. Ludolph van der Hoeven, held at Dr. Sunderman, Sr.'s home on Delancey Place.  An editorial on music was presented by Dr Sunderman (see section on music).

The Association of Clinical Scientists - 1985

Meeting Number 74. - May 9-12, 1985; Sheraton-Islander Hotel; Brown University Medical School; Newport, RI

Meeting Number 75. - Oct 9-13, 1985; Galt House Hotel; Humana-Audubon Hospital; Louisville, KY (Laboratory Diagnosis of Cardiovascular Disorders)

President - Egil Fosslien MD

Vice-President - David E Bruns MD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

GOLD-HEADED CANE AWARD Michael M Lubran MD PhD

CLINICAL SCIENTIST OF THE YEAR Irene E Roeckel MD

DIPLOMA OF HONOR Ernest M Walker Jr MD PhD

DIPLOMA OF HONOR Israel Diamond MD

YOUNG CLINICAL SCIENTIST AWARD James C Boyd MD

ABRAHAM J GITLITZ MEMORIAL LECTURESHIP Philippe A Grandjean MD PhD "Reference Intervals for Toxic Metals in Body Fluids and Tissues."

CLAUDE P BROWN MEMORIAL LECTURESHIP David J Morris PhD "Studies on Aldosterone Metabolism."

HISTORY OF THE ASSOCIATION OF CLINICAL SCIENTISTS

(1985-1988)

Donald J. Cannon, Ph.D.

Laboratory medicine in the mid 1980's was both flourishing and yet under an ominous cloud. Economic recovery was evident in the offerings of the diagnostic industry but the presence and promise of increasing government regulation was looming on the horizon. The Association of Clinical Scientists, although not oblivious to its surroundings, was progressing very nicely. Membership was increasing and many of the new fellows were young and brimming with ideas and enthusiasm - membership in Arkansas alone tripled in the past few years. For its 74th meeting (May 1985), the Association made only its fourth trip to New England and first to the small but beautiful state of Rhode Island. In one of New England's most picturesque and nautical towns the old goats and young turks gathered on Goat Island for an exciting and memorable Spring meeting.. Under the able guidance of Bill Griffiths and with the contributions of the faculty at Brown University, the assembled members were brought up to date in molecular genetics, trace metals and environmental pathology to name but a few topics. Philippe Grandjean presented the Gitlitz lecture on toxic metals and David Morris, the Brown lecture on aldosterone. Exploring and touring Newport was delightful as the weather was very cooperative. The banquet highlights included awards to Mike Lubran and Israel Diamond who was the guest speaker. In the 300th anniversary year of the births of both Bach and Handel, the latter was represented (sonata) at the meeting musicale amidst a very eclectic program designed by the inimitable Ludolph van der Hoeven. Emerging to the sounds of crashing surf was a delightful ending to this annual event. On the final day the organization officially doubled to four the number of scientific sections - a move that in later years would prove very fruitful to the organizations' progress. Enthusiasm for the fall meeting in Louisville was evident as attendees left for home.

Louisville, Kentucky lies just south of the Mason-Dixon Line and provided an ideal location for the fall 1985 applied seminar on the diagnosis of cardiovascular disorders. The home city of Humana Hospital where many cardiovascular surgical techniques and devices were invented or perfected was an ideal setting. Presentations on heart transplantation and implantations highlighted the opening day and set the tone for future activities. In retrospect the amount of information and material packed into those five days has not been matched since. The discussions on diagnostic testing are fascinating retrospectives as viewed from the present climate of new and controversial markers for cardiovascular disease. The hands-on demonstrations were both timely and useful and the range of member expertise and interests, as exemplified by the many and varied presentations, was most impressive to this attendee.

The bourbon flowed at the banquet as Dr. Sunderman became an honorary Kentucky colonel and Irene Roeckel, Ernie Walker and Jim Boyd received much deserved awards. A memorable meeting with visits to Churchill Downs and the horse farms, much walking by the very active auxiliary, and more great chamber music were all just icing on the cake. 1985 ended with 82 new fellows, 748 total members, over $50,000 in the treasury, six scientific sections and the fifth volume of Bernie Gondos and his newsletter musings. The efforts of outgoing president Egil Fosslien and the indefatigable Martha-Lee Sunderman were much appreciated by all.

In 1986, Ronald Reagan was president of the United States, Bill Clinton was the governor of Arkansas and the Excelsior Hotel in Little Rock had opened the previous year and hosted the Association's spring meeting - history in the making somewhere here. Ernie Walker and Don Cannon welcomed an enthusiastic group to the Medical School and VA complex. University faculty led by Aubrey Hough (Claude Brown lecture), Marge Brewster, Alex Pappas and Ned Fody provided scintillating presenta-tions and topics ranged from osteogenesis to hypernickelemia to robotic whole blood analysis. Toxicology permeated if not dominated the meeting both in lectures and in the visit and scientific presentations at the National Center for Toxicological Research. Touring and diamond mining occupied the auxiliary and the banquet featured much humor, an award to Marge Brewster, a retrospective by Howard Quittner who hosted a meeting eighteen years earlier in Little Rock and a keynote address by Gene Towbin of the VA Medical Center. Music as always was entertaining, highlighting Mozart, Bach and Beethoven and filling the hotel with great sounds. With thirty-seven new fellows, the membership was excited about the fall seminar in Atlanta and the chance to learn about nucleic acid probes and monoclonal antibodies. Other lucky members were excited about the June trip to Bermuda.

Finally, November 1986 brought a new and exciting topic to the seminar series - probes and antibodies applied to human diseases. Bob Hunter and Dave Bruns at Emory University in Atlanta organized an excellent, comprehensive program on a subject that many had less knowledge of than the usual areas discussed at the fall seminars but much enthusiasm to learn. In this atmosphere all objectives were reached through over 50 presentations, 16 demos and an all day wet workshop. The problems, potentials, pitfalls and pursuit of molecular diagnostics in clinical pathology were all there for our edification and enjoyment (bewilderment). For many the future was now. Jasper See, Don Forman and Steve Wong received awards at the meeting banquet and the assembled heard a fascinating talk on primates and related research from Dr. King, director of the Yerkes Primate Center. The musicale was, as always, delightful, the business meeting unusually exciting and future meeting plans intriguing . Vendors and meeting organizers were duly acknowledged with special thanks to Mike Ladzinski, Bill Sunderman Jr. and outgoing president Dave Bruns.

Ah to be in Charleston in May 1987 - which is just where we all were if we attended the 80th meeting of the Association hosted by Dick Gadsden and Armand Glassman. In a slight twist from the usual, the meeting began with a cruise and tour of Fort Sumter, followed by hospital and laboratory tours - quite nice actually, should be revisited some day. The scientific part of the meeting saw the emergence of well organized sections sponsoring individual sessions, a practice tried previously but very well done at this meeting. Immunohematology, clinical science in community hospitals and toxicology and therapeutics (unofficial new section) were the sponsors with six talks per colloquia at the medical school. The next day at the hotel John Lazarchick lectured on flow cytometry (Gitlitz), Egil Fosslien on apolipoproteins (Keynote) and John Manos on influenza (Keynote). Interspersed were many presentations covering a wide range of the memberships' research interests. The musicale contained instrumental and vocal pieces, poetry readings, and artistic exhibitions - an absolutely delightful change of pace - viva Ludolph! The reception and banquet were humorous, well attended and highlighted by a presentation on the space program. Sunday brought the sporadic, athletic part of the meeting as many ran/walked along the Battery in the Run-for-the-Lilies. Survivors of this activity attended the business meeting at which the organizers and vendor sponsors were recognized.

I imagine if you are going to sponsor a meeting in mid-November why not Tampa! And thus another brilliant location for the Association. At one of the most well attended meetings in recent memory clinical and analytical toxicology was thoroughly dissected from George Lumb's opening discussion of environmental hazards to presentations on toxic agents, toxicokinetics and analytical methods. The wide range of knowledge and experience of the membership was fully observed in the 18 demonstrations and separate workshop that were held on two mornings. Thursday's formal banquet featured an inspiring account by Dr. Mattison of Tampa of his experiences at the Schweitzer Hospital in Lambarene. Awards to Dave Bruns, Bob Hunter and Howard Taylor were well received and appreciated. Friday afternoon included a tour of Busch Gardens followed by a memorable tour and dinner-reception at the Moffitt Cancer Center. The fall 1987 meeting saw the maturation of the scientific sections who each held short organizational meetings and gave reports at the Saturday business meeting - an enthusiastic and productive group under John Klavins’ guidance. The business meeting was very well attended (SRO), dues were increased minimally, the treasury balance is over $52,000 and the membership was a healthy 743 although fewer fellows were added. It should be mentioned that twice a year at the business meeting a moment of silence is observed for deceased members. The musicale Saturday evening was as usual professional and an outstanding bargain! The meeting continued until 3 pm on Sunday such was the topic interest and enthusiasm. Many thanks were distributed including Emily Gadsden and the auxiliary officers, Ernie Walker for his memorable reign and to John Shively and Jeno Szakacs for their tireless efforts in producing an outstanding seminar.

Although the Association membership is made up of many wise men and women, some members can be cantankerous. In order to calm the vociferous members who emigrated to the west, the 1988 Spring (84th) meeting was held in Newport Beach, California - a risky venture to be sure what with all that areas natural disasters but a boisterous crowd did gather in one of the prettiest locations on the "other" coast. Rumor had it that certain eastern oriented members thought they were going back to Rhode Island! Paul Fu, Byron Myrhe and Mike Lubran proved to be superior hosts and immediately grabbed everyone's attention with an opening tour of the Nichols Institute in San Juan Capistrano (the swallows, nowhere to be seen, had obviously been forewarned). This interesting trip featured a lecture by Dr. Fujimura on molecular hybridization as well as some high tech analytical methods. This was followed in the afternoon by a tour of the R&D and production facilities of Beckman Instruments in Brea. The hospitality was outstanding (thank you Nate Gochman) and the presentations excellent - the "customers" were duly impressed. That evening at a dinner held in conjunction with the American Association for Clinical Chemistry, Egil Fosslien was featured speaker on atherosclerosis. One of the nicest meeting kickoffs in a long time. The bubble burst with Armand Glassman's keynote lecture at 8:10 am the next morning and it was back to reality. Immunohematology, molecular biology, clinical chemistry (again with the AACC) and toxicology filled the day very nicely with new ideas and information. Bill Sunderman Jr presented the Brown lecture on oncogenes, finger loops and metals. The evening ended with an elegant wine and cheese reception accompanied by the usual soothing music of the Association's most talented musicians (and friends). Great science continued on Saturday covering tissue pathology, microbiology and occupational medicine. Interspersed were committee meetings and the day culminated at the black tie optional banquet in a most beautiful setting where Armand Glassman received the Association's Diploma of Honor award. The banquet address was a fascinating account of Inca medicine by Dr. Albites accompanied by stunning photographs. Sunday brought the Run-for-the-lilies and the business meeting (the newsletter editor has returned from his stint as an author) and planning sessions for the fall.

Certain wags might describe the fall meeting of the Association as a bloody meeting and in a way that would be correct. Diagnostic hematology was the theme for the 88th meeting held in Hartford, Connecticut. Now before we proceed, the mathematically challenged may wonder how an organization can have an 84th meeting in the Spring and an 88th meeting in the fall. Did we miss something? Yes, the Association is truly an international one and co-sponsors meetings outside the United States at which the organization has an interest and where members are active. In the summer of 1988 there were three such meetings, in Yugoslavia, Finland and Sweden. Voila! 84 to 88. Back to Hartford and a superb retrospective and prospective view of hematology was presented under the tutelage of Ed Morse and his committee. Molecular and chemical diagnosis, transfusion medicine, cell diagnosis, coagulation, bone marrow transplantation and tissue pathology were covered in lectures, demonstrations, and workshops. Tours of the Red Cross Blood Center and the University of Connecticut were weaved into the theme very smoothly. Optional tours including the Mark Twain House were enjoyed by all. The banquet saw awards presented to Kendall Kane, Ed Morse and Ray Dorio, all of whom acknowledged their gratitude to the Association and their fellow members. The dean of the School of Medicine, Dr. Massey, presented the banquet address on excellence vs. preeminence, a most stimulating topic. The health of the Association was revealed at the business meeting as the treasury is over $58,000, the membership at 747 and the sections very active. After extending appreciation and gratitudes to Ed Morse, outgoing president Bob Hunter and Bill Sunderman Sr, attendees parted in high spirits to meet again in the spring in Charlottesville, Virginia.

The Association of Clinical Scientists – 1986

Meeting Number 76. - April 23-26, 1986; Ischia, Italy (Third International Conference on Human Tumor Markers)

Meeting Number 77. - May 15-18, 1986; Excelsior Hotel; University of Arkansas Medical School; Little Rock, AR

Meeting Number 78. - July 28-Aug 1, 1986; University of Occupational and Environmental Health; Kitakyushu, Japan (3rd Intern. Conf. on Clinical Chemistry and Chemical Toxicology of Metals)

Meeting Number 79. - Nov 13-16, 1986; Colony Square Hotel; Emory University School of Medicine; Atlanta, GA (Nucleic Acid Probes and Monoclonal Antibodies in Human Disease)

President - David E Bruns MD

Vice-President - Ernest M Walker Jr MD PhD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Donald T Forman PhD

DIPLOMA OF HONOR Jasper G Chen See MD

DIPLOMA OF HONOR Marge A Brewster PhD and

YOUNG CLINICAL SCIENTIST AWARD Steven H-Y Wong PhD

CLAUDE P BROWN MEMORIAL LECTURESHIP Aubrey J Hough Jr MD"Aging Phenomena in Joints and Osteoarthritis: Cause or Coincidence?"

The Association of Clinical Scientists - 1987

Meeting Number 80. - May 14-17, 1987; Charleston Place; Medical University of South Carolina; Charleston, SC

Meeting Number 81. - Aug 17-21, 1987; Odense University, Denmark (Symposium on Trace Elements in Human Health & Disease)

Meeting Number 82. - Aug 25-28, 1987; Omni Park Hotel; New York City, NY (4th International Conference on Human Tumor Markers)

Meeting Number 83. - Nov 12-15, 1987; Lincoln Hotel; Tampa, FL (Applied Seminar on Analytical and Clinical Toxicology)

President - Ernest M Walker Jr MD PhD

Vice-President - Robert L Hunter Jr MD PhD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR David E Bruns MD

DIPLOMA OF HONOR Armand B Glassman MD

DIPLOMA OF HONOR Robert L Hunter Jr MD, PhD

YOUNG CLINICAL SCIENTIST AWARD E Howard Taylor PhD

ABRAHAM J GITLITZ MEMORIAL LECTURESHIP John Lazarchick MD "Flow Cytometric Analysis: Utility in Detection of Platelet Antibodies."

The Association of Clinical Scientists - 1988

Meeting Number 84. - May 12-15, 1988; Newporter Resort; UCLA Medical School; Nichols Institute; Beckman Instruments, Newport Beach, CA

Meeting Number 85. - May 29-June 3, 1988; Brioni Hotel; Brioni, Yugoslavia (Symposium on Drugs in Competitive Athletics)

Meeting Number 86. - Sept 5-9, 1988; Hanasaari Centre, Espoo, Helsinki, Finland (4th International Conference on the Metabolism and Toxicology of Nickel)

Meeting Number 87. - Sept 19-23, 1988; Stockholm, Sweden (5th International Conference on Human Tumor Markers)

Meeting Number 88. - Nov 10-13, 1988; Parkview-Hilton Hotel, Hartford; University of Connecticut Medical School, Farmington, CT; (Applied Seminar on Diagnostic Hematology)

President - Robert L Hunter Jr MD PhD

Vice-President - William C Griffiths PhD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Kendall Kane MD

DIPLOMA OF HONOR Edward E Morse MD

YOUNG CLINICAL SCIENTIST AWARD Raymond J Dorio MD

CLAUDE P BROWN MEMORIAL LECTURESHIP F William Sunderman Jr MD "Oncogenes, Finger-Loops, and Metals."

The Association of Clinical Scientists – 1989

For the Association of Clinical Scientists, the year 1989 began quietly with a meeting of the executive committee in the Sheraton hotel at the airport in Hartford, with William Griffiths as president. Two innovations were reported at the meeting, the computerization of membership records by the secretary-treasurer and a revised membership brochure by the chairman of the membership committee, Sidney Hopfer.

Meeting Number 89. - May 11-14, 1989; Omni Hotel; University of Virginia Medical School; Charlottesville, VA

Meeting Number 90. - May 23-26, 1989; Miyako Hotel, Tokyo, Japan (6th International Conference on Human Tumor Markers)

Meeting Number 91. - November 16-19, 1989; Hershey Philadelphia Hotel, Philadelphia, PA (Fortieth Anniversary; Applied Seminar on Laboratory Diagnosis of Diseases of the Liver)

President - William C Griffiths PhD

Vice-President - Frederick Muschenheim MD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

GOLD-HEADED CANE AWARD Wallace H Coulter PhD

CLINICAL SCIENTIST OF THE YEAR Robert L Hunter Jr MD PhD

DIPLOMA OF HONOR Richard H Gadsden Sr PhD

YOUNG CLINICAL SCIENTIST AWARD Robin A Felder PhD

ABRAHAM J GITLITZ MEMORIAL LECTURESHIP Robert E Fechner MD "Carcinoma-in-Situ: An Outmoded Diagnosis."

CLAUDE P BROWN MEMORIAL LECTURESHIP Thomas W Tillack MD "Glycolipid Organization in Membranes and Lipid Bilayers Studied by Freeze-Etching."

Meeting Number 89. - May 11-14, 1989; Omni Hotel; University of Virginia Medical School; Charlottesville, VA

The spring meeting was held in Charlottesville, VA, at the Omni hotel. The sunny southern climate customary to the date (May 11-14) was nowhere to be found as participants assembled.  The meeting, chaired by David Bruns, was outstanding and made up for the cold temperatures. An innovation was the first program by the Scientific Section on Cell and Tissue Pathology, chaired by Bernard Gondos and Peter Farmer, including a session on the main program and four talks by distinguished members of the faculty at the University of Virginia. An important but unusual program at the meeting was a talk by Daniel Seckinger, who subsequently became president of the College of American Pathologists, for the Section on Clinical Science in Practice. Dr. Seckinger introduced those present to the concepts of capitated reimbursement and described methods for calculating bids for laboratory services under capitation. The non-technical program included the customary excellent musicale as well as an excursion to the Barboursville winery and James Madison's house. At the banquet, Dr. Kenneth Crispell shared his interest in and knowledge of "Hidden Illnesses in the White House." Many fellows of the Association took advantage of their visit to Charlottesville to tour Thomas Jefferson's Monticello and the nearby home of James Monroe. Some courageous members took an early morning excursion to survey the environs by balloon.

Meeting Number 90. - May 23-26, 1989; Miyako Hotel, Tokyo, Japan (6th International Conference on Human Tumor Markers)

Meeting Number 91. - November 16-19, 1989; Hershey Philadelphia Hotel, Philadelphia, PA (Fortieth Anniversary; Applied Seminar on Laboratory Diagnosis of Diseases of the Liver)

The 1989 fall meeting in Philadelphia was memorable because it marked the 40th anniversary of the Association. The event was celebrated by a Madeira party at the Union League club. Dr. Herbert Derman, a past-president and founding member of the Association, was banquet speaker. He shared his reminiscences about the early days of the Association. Dr. Sunderman Sr. described the historic traditions of Madeira parties in Philadelphia and supervised the pouring of the libations. The banquet was notable also for the presentation of a gold-headed cane to Dr. Wallace Coulter, inventor of the electric impedance particle counter used in clinical laboratories for the enumeration of blood cells.

The musicale at this meeting was also memorable, since it was held in the auditorium of the Curtis Institute. The Brahms Horn Trio, played by Dr. Sunderman, Sr., and the head of the Brass Department at the Institute was unforgettable. To add to the pleasures of the fall meeting, Mrs. Sunderman made sure that tickets were available for other musical events held in Philadelphia during the meeting. Participants were also treated to a tour of important historical sites in the city.

The scientific program, entitled, "Seminar on Laboratory Diagnosis of Diseases of the Liver," included 12 demonstrations of methodology as well as the usual bonanza of technical papers. Unfortunately, the opportunity to study the hepatic effects of Madeira was lost at the meeting, an omission that may be repairable in future years.

The Association of Clinical Scientists - 1990

The Association's year in 1990 began in January in Syracuse, New York, with a meeting of the executive committee. Before the meeting, Fred Muschenheim, the president, sent an elaborate questionnaire to committee members as a basis for reconsidering the goals, objectives, and activities of the Association. The concrete results of this effort included a recommendation that has since been put in practice, that the award for the Young Clinical Scientist of the Year should be based on presentations at the spring meeting. Another recommendation was that the vice-president of the Association should chair the second half of each executive committee meeting, when the regional delegates and heads of scientific sections join the core members of the committee. This suggestion was honored only at the next meeting. The executive committee had a memorable dinner at the Brewster Inn in Cazenovia, where they were joined by members of the local program committee for the forthcoming Syracuse meeting in May, 1992. The dinner ended with presentation to Dr. Sunderman, Sr. of a bottle of Madeira, which he promptly shared with the dinner guests in compliance with the traditions of Madeira parties in Philadelphia.

During the spring of 1990, the president represented the Association at the opening of the new College of American Pathologist's headquarters building in Northfield, IL. by invitation of Al Free, he also represented the Association at "Healthy People 2000" in Washington, DC. This meeting, hosted by Louis Sullivan, MD, Secretary of the Department of Health and Human Services, was convened to set the agenda for health care in the United States for the following 10 years.

Meeting Number 92. - May 10-13, 1990; Meridien Hotel; University of British Columbia Faculty of Medicine, Vancouver, BC, Canada

Meeting Number 93. - June 5-8, 1990; Hanasaari Centre, Espoo, Helsinki, Finland (4th International Symposium on Trace Elements in Health and Disease)

Meeting Number 94. - September 10-14, 1990; Hotel Rus, Kiev, Russia (7th Intern. Conference on Human Tumor Markers)

Meeting Number 95. - November 7-11, 1990; Clarion Hotel, Cincinnati, OH (Laboratory Diagnosis of Disorders of the Fetus, Newborn, and Early Childhood)

President - Frederick Muschenheim MD

Vice-President - Armand B Glassman MD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR William C Griffiths PhD

DIPLOMA OF HONOR Ludolph H van der Hoeven MD PhD

YOUNG CLINICAL SCIENTIST AWARD Carolyn M Salafia MD

ABRAHAM J GITLITZ MEMORIAL LECTURESHIP Michael R Hayden MB PhD "Molecular Biology of Huntington's Disease."

Meeting Number 92. - May 10-13, 1990; Meridien Hotel; University of British Columbia Faculty of Medicine, Vancouver, BC, Canada

The spring meeting, May 10 to 13, was noteworthy as the first meeting of the Association held outside the territory of the United States. It was, in fact, not far from the border, in Vancouver, British Columbia. Host Peter Stonier arranged an outstanding meeting. The Meridien hotel in Vancouver was one of the nicest that the Association has used. The excellent Chinese and other local restaurants were sampled extensively by the participants. An excursion by ferry to Vancouver Island and the city of Victoria provided a unique shipboard venue for scientific section meetings. Stops were made at Butchart Gardens and the Royal British Columbia Museum, with its superbly displayed collection of Northwest Indian artifacts.

The scientific program in Vancouver was especially memorable for contributions by the local scientific community, including a lymphoma tutorial by Alexander Pontifex and Lawrence Haley at St. Paul's Hospital, and a talk on asbestos and mesothelioma by Andrew Churg. Another topic of interest to Americans was a talk on, "Laboratory Utilization in British Columbia," by Dr. Duncan Innes, describing the effects of the province's health care system on clinical laboratories.

The cultural program proved that music can be played and heard in Canada as well as the United States, with the customary excellent musicale. The banquet address, given by Roy Tanami of the Royal Vancouver Aquarium on, "Animal Adventures in the Arctic," stimulated many participants who could spare the time to visit the aquarium.

The meeting was blessed with fine weather, which is not inevitable in Vancouver. This changed on Sunday morning, which was scheduled, unfortunately, as the time for the "Run for the Lilies." The run was held despite the rain, and it was appropriate when the trophies were subsequently sent by mail that they depicted swimmers instead of runners.

The spring meeting of 1990 was associated with two Association landmarks. One was the rebirth of the Association's newsletter as The Trumpet, a title it has retained since that time, under the editorship of the Secretary-Treasurer. The other was the availability of the Association's first tie. Unfortunately, customs regulations prevented selling the tie at the meeting in Canada, but orders were taken and the ties delivered by mail.

Meeting Number 95 – November 7-11, 1990:  Clarion Hotel, Cincinnati, OH.

The fall meeting of 1990 was held at the Clarion Hotel in Cincinnati, November 7 to 11. Hosted by Donald Cannon and a strong local committee, the meeting's topic was "Diseases of the Fetus, Newborn, and Early Childhood." Early registrants on Wednesday were treated to a dinner at the University of Cincinnati Faculty Club, followed by a tour of the new neonatal intensive care unit at the University's hospital. It was clear that no expense had been spared in building the unit, which was impressive for its size, structure, and equipment.

The meeting's scientific program was excellent, and included both papers and demonstrations of methodology. The program was so full it extended through the whole morning on Sunday.

The non-scientific program included a tour to the Wright-Patterson Air Force museum in Dayton as well as the usual excellent musicale, with Dr. van der Hoeven, the program chairman, on his home turf. Many participants took advantage of the trip to Cincinnati to see the painting collection at the Taft museum.

At the Association's business meeting, the president reported the establishment of the Sunderman Fund at the Bermuda Biological Station for Research, with the objective of establishing the Sunderman Seminar Room at the Biological Station in 1992. This project subsequently was completed, and the Sunderman Fund continues to raise money to support the maintenance of the Seminar Room. Dr. Sunderman, Sr. reported on discussions with ACLPS concerning possible cosponsorship of the Annals, a proposal that was ultimately rejected by the Association.


Editorial

THE ASSOCIATION OF CLINICAL SCIENTISTS--

A PERSPECTIVE

The Association of Clinical Scientists is a professional organization with approximately 800 members who have a M. D. or Ph.D. degree and have an interest in clinical science and laboratory medicine. It was organized approximately 40 years ago as a "Clinical Science Club" with informal meetings and became a non-profit scientific organization in 1957. There are regular semi-annual meetings with a Spring meeting that consists of scientific presentations by members and guest speakers and an applied seminar and workshop in the Fall. A bimonthly journal, Annals of Clinical and Laboratory Science, has been published as its official journal for the past 20 years. The organization and leadership of the Association has been primarily due to the skills and personal contributions of F William Sunderman, M.D., Ph.D. who, as a role model, has been a significant factor in the growth and continued vigor of the organization.

As the leadership moves from its current presence and a developing legacy to the inevitable memorials of the future, what are the unique or unusual attributes that have contributed to and sustained this relatively small, but dynamic professional organization? It has always provided a peer relation ship of physicians and the clinical laboratory scientist with a doctoral degree; furthermore, the workshops for the development or honing of technical or laboratory skills have been an integral part of the Association's activities from its very onset. But what are the truly unique characteristics of the Association and its members?

The majority of members are practicing clinical scientists with varying amounts of educational and research activities or experiences, but with no Nobel prize winners! All are interested in their own continuing education and new developments in laboratory medicine. As a group, the members exhibit a sense of curiosity with a pursuit of excellence in all their activities. Many discipline themselves to present reviews and their research at the meetings of the Association, many times responding to the sustained and frequently not so subtle prodding of Dr. Sunderman in his role as the Association's Director of Education! In general, the members have strong clinical interests with the majority having people-oriented personalities and a focus not only on science and research in its relation to the practice of medicine, but also on one of the highest attributes of our Judeo-Christian tradition, caring for people, i.e., our patients and our colleagues. This characteristic has resulted in the relatively small size of the organization as an acceptable modification of a clinical science club that has maintained a personal fellowship aura of its membership rather than the impersonality of a large national group.

Another, but similar, attribute of the group includes the cultural activities that are an integral part of each meeting, i.e., a day or afternoon free to visit the attractions, cultural treasures and historical aspects of the host city. This is designed for the members of the Association, and not only their spouses as is the usual practice of many other scientific organizations. Equally important and unique are the musicales, recitals, chamber music, etc. presented by the Association members, spouses, and occasionally a guest as a traditional part of an evening program. All of these reflect the unusual characteristics of the Association, the merging of the science in laboratory medicine and the arts of our heritage. The biannual field trips to the Bermuda Biological Station for Research are an example of an activity that attracts those members who are interested in the ecological aspects of an unusual microcosm that represents worldwide issues or concerns and at the same time provides the opportunity to cherish the fellowship of colleagues and their spouses.

In summary, the Association consists of a group of clinical scientists who are intellectually curious or inquisitive, care for people and their colleagues, cherish the fellowship of small groups, pursue personal excellence in their practice, discipline themselves to share their thoughts and research with their fellow professionals by both the oral and written word and support an unique mixture of science and the humanities in their programs which is a reflection of their interest in the arts of living and the science of medicine.

John A. Shively M.D.

(ANNALS OF CLINICAL AND LABORATORY SCIENCE. 20:427-428, 1990)

The Association of Clinical Scientists – 1991

The Gramercy Park Hotel was the venue for the executive committee's midwinter meeting in 1991. President Armand Glassman highlighted the meeting with a discussion of the desirability of establishing a headquarters building for the association. After considerable debate, it was decided that the Association would not undertake the project at that time, although the possibility remained open for the future.

Meeting Number 96. - May 8-12, 1991; Red Lion Hotel; University of Utah Medical School; Salt Lake City, UT

Meeting Number 97. - September 9-12,1991; Triaena Congress Centre, Athens, Greece (International Congress on 25 Years of Immunoenzymatic Techniques)

Meeting Number 98. - November 14-17, 1991; Omni Jacksonville FL (Six Major Advances in Laboratory Diagnosis and Their Clinical Applications)

President - Armand B Glassman MD

Vice-President - Peter M Farmer MD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Ernest M Walker Jr MD PhD

DIPLOMA OF HONOR Frederick Muschenheim MD

DIPLOMA OF HONOR Helen M Free DSc

YOUNG CLINICAL SCIENTIST AWARD Juliana G Szakacs MD

CLAUDE P BROWN MEMORIAL LECTURESHIP Raymond L White PhD "Identification of the Gene Responsible for Neurofibromatosis Type I."

Meeting Number 96. - May 8-12, 1991; Red Lion Hotel; University of Utah Medical School; Salt Lake City, UT

The spring meeting was held in Salt Lake City May 8 to 12, with Drs. Joseph Knight and James and Lily Wu as hosts. The cultural program was particularly memorable, not only for the Association's musicale, but also for chances to hear the Mormon Tabernacle Choir. The participants dined on Thursday evening at the Lion House, the home of Brigham Young, and attended a rehearsal of the choir. On Sunday morning, many participants were able to attend the choir's broadcast at the Tabernacle.

The Mormon Church maintains a massive genealogical center, the world's largest. It is a fertile source for conducting research in genetic diseases, as demonstrated by Lily Wu's papers on LDL receptors and Apoprotein E, and on dyslipidemia which were a highlight of the scientific program. A workshop on renal pathology was especially enjoyable. Participants were treated to a tour of ARUP laboratory and heard a discussion by John Matsen on development of the Associated Regional and University Pathologists laboratory.

The "Run for the Lilies" was held in a park near the University, although some of the flatlanders walked rather than ran.

Meeting Number 97. - September 9-12,1991; Triaena Congress Centre, Athens, Greece (International Congress on 25 Years of Immunoenzymatic Techniques)

Meeting Number 98. - November 14-17, 1991; Omni Jacksonville FL (Six Major Advances in Laboratory Diagnosis and Their Clinical Applications)

The fall meeting in 1991 was hosted by James Humes at the Omni Hotel in Jacksonville. It featured a novel program in that it covered, not analytes directly, but rather six new methods of analysis. The message was the medium. The methods were polymerase chain reaction technology for nucleic acids, restriction fragment length polymorphism, nucleic acid hybridization in histological sections, high performance electrophoresis, flow cytometry, and gas chromatography/mass spectrometry. Workshops in the six techniques were a major part of the program. The innovative format was received enthusiastically by the participants, and the meeting was characterized by an unusually high proportion of papers by fellows of the Association, but also by heavy dependence on equipment manufacturers for explanation of their products.

Highlight of the cultural program was a trip to historic St. Augustine, followed by a buffet dinner at the Ponce de Leon Resort.

At the business meeting in Jacksonville, Dr. Sunderman, Jr. announced removal of the Association's offices from the University of Connecticut and the hiring of Beryl Ierardi as secretary in a new headquarters office in Farmington. This arrangement lasted until 1995, when Ms. Ierardi's husband's work required the family to leave Farmington.

In summary, 1989-1991 were good years for the Association. Meetings were excellent. They were held in interesting locations and had interesting programs, so that they were both culturally and scientifically outstanding. The Association experienced a number of incremental improvements and changes, but the period was marked by structural stability. 

The Association of Clinical Scientists – 1992

Meeting Number 99. - May 13-17, 1992; Sheraton University Inn, Medical School of the State University of New York, Syracuse NY

Meeting Number 100. - Sept 6-10, 1992; Vienna, Austria (9thInternational Conference on Human Tumor Markers)

Meeting Number 101. - Nov 11-15, 1992; Fess Parker's Red Lion Resort and Sansum Medical Foundation, Santa Barbara, CA (Laboratory Diagnosis of Metabolic Disorders, Emphasizing Diabetes Mellitus)

President - Peter M Farmer MD

Vice-President - Byron A Myhre MD PhD

Secretary-Treasurer F William Sunderman Jr MD

Auxiliary President - Diane Lorincz

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Peter J Goldblatt MD

DIPLOMA OF HONOR Donald J Cannon PhD

YOUNG CLINICAL SCIENTIST AWARD Betty A Forbes PhD

ABRAHAM J GITLITZ MEMORIAL LECTURESHIP Jonathan L Miller MD PhD "Molecular Pathology of the Platelet von Willebrand Factor Receptor."

Meeting Number 99. - May 13-17, 1992; Sheraton University Inn, Medical School of the State University of New York, Syracuse NY

The Spring Meeting was held on May 13-17,1992 at the Sheraton University Inn, in conjunction with the Medical School of SUNY, Syracuse N.Y. The theme was "Frontiers in Clinical Science." The Gitlitz Memorial Lecture was presented by Jonathan L. Miller M.D., Ph.D. who spoke on "Molecular Pathology of the Platelet von Willebrand Factor Receptor" The traditional Tour was arranged by Dr. Muschenheimer and involved an excursion to the Oneida Mansion house of the Oneida Colony (with lunch) and a tour of Fort Stanwix. The banquet speaker was our good friend, John B. Henry M.D. who spoke on "Medical Informatics: Challenges and Opportunities for Clinical Scientists." The Musicale was held at Crouse Conservatory of Music Concert Hall, a gorgeous old brick building with a very large stage and beautiful acoustics.

Meeting Number 100. - Sept 6-10, 1992; Vienna, Austria (9thInternational Conference on Human Tumor Markers)

Meeting Number 101. - Nov 11-15, 1992; Fess Parker's Red Lion Resort and Sansum Medical Foundation, Santa Barbara, CA (Laboratory Diagnosis of Metabolic Disorders, Emphasizing Diabetes Mellitus)

The Fall Meeting was held on Nov 11-15, 1992 at Fess Parker's Red Lion Resort and at the Sansum Medical Foundation, in Santa Barbara CA. The title of the conference was "Laboratory Diagnosis of Metabolic Disorders, Emphasizing Diabetes Mellitus" and a tour of the Sansum Medical Foundation was one of the treats. The traditional Tour was a Trip to the Santa Ynez Mountains with wine tasting and dinner at the Gayney Winery. At the conclusion of the tour, the complimentary glasses were taken home as a remembrance of the trip.

The banquet Lecturer was Dr. Robert Failing a Santa Barbara pathologist and Coroner's Physician. His title "High Points in Mountaineering" tells us that it was illustrated by many pictures of mountain climbing. Dr. Failing has climbed the highest mountain in each state and the highest mountain in every continent except for Asia (Mt. Everest).

For the first time ever, an Association Tennis Tournament was arranged by Dr. Gondos. Scores and winners are not recorded.

The Association of Clinical Scientists – 1993

Meeting Number 102. - May 12-16, 1993; Newport Islander Doubletree Hotel , Brown University Medical School, Newport, RI

Meeting Number 103. - Sept 6-10, 1993; Bonn, Germany (10th Inter-national Conference on Human Tumor Markers)

Meeting Number 104. - Nov 3-7, 1993; Hilton Hotel, Medical College of Ohio, Toledo, Ohio (Advances in the Laboratory Diagnosis of Cancer and Their Clinical Applications)

President - Byron A Myhre MD PhD

Vice-President - Peter J Goldblatt MD

Secretary-Treasurer F William Sunderman Jr MD

Auxiliary President - Alberta Glassman

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Armand B Glassman MD

DIPLOMA OF HONOR Andrew E Lorincz MD

YOUNG CLINICAL SCIENTIST AWARD Joseph P Laurino PhD and

YOUNG CLINICAL SCIENTIST AWARD Terrence N Moyana MB

CLAUDE P BROWN MEMORIAL LECTURESHIP Abby L Maizel MD PhD "Human B Cell Neoplasia: An Escape from Normal Control."

Meeting Number 102. - May 12-16, 1993; Newport Islander Doubletree Hotel , Brown University Medical School, Newport, RI

The Spring Meeting was held on May 12-16, 1993 at the Newport Islander Doubletree Hotel and was sponsored by Brown University Medical School, Newport, RI. The title was "Frontiers in Clinical Science" The hotel occupies a lovely location on a point of land jutting out into the bay with the squid fishermen lining the bridge leading to the hotel.

The Claude Brown Memorial Lectureship was given by Abby L Maizel M.D., Ph.D. and was entitled "Human B. Cell Neoplasia: An Escape from Normal Control" A stellar program followed. The Tour was of Historic Newport and included a tour of several of the "Cottages" of the wealthy New Yorkers who used to spend their summers in Newport.

A unique event was the Informal Barbeque Buffet for New Members. The Banquet Lecture was by James Humes M.D. and was entitled "The Kennedy Assassination - A Thirty Year Perspective". Dr. Humes has remained silent on this for many years, but published his findings in a recent article in JAMA that attempted to clear up some of the confusion that has arisen, and was created by some who did not know the facts very well. It was a fascinating lecture.

Meeting Number 103. - Sept 6-10, 1993; Bonn, Germany (10th Inter-national Conference on Human Tumor Markers)

Meeting Number 104. - Nov 3-7, 1993; Hilton Hotel, Medical College of Ohio, Toledo, Ohio (Advances in the Laboratory Diagnosis of Cancer and Their Clinical Applications)

The Fall Meeting was held on Nov. 2-7,1993 at the Hilton Hotel, and sponsored by the Medical College of Ohio, Toledo Ohio. The title was "Advances in the Laboratory Diagnosis of Cancer and their Clinical Applications". The hotel is somewhat unique in that it is on the campus of the Medical School and meetings can be held there or one can take the underground tunnels and go directly to the Medical School.

The Tour started at the Toledo Museum of Art, where we were able to view the history of glass as shown by its artifacts and then went to the Labino Studio and Gallery where we were given a lecture and demonstration on how glass objects are made today. Later, we could buy some of the items. This was followed by a mid Eastern Banquet including the traditional belly dancer.

Byron Myhre M.D.,Ph.D. presided at the formal banquet held at the hotel. He presented the following awards: Clinical Scientist of the Year - Armand B. Glassman, M.D. Diploma of Honor - Andrew E. Lorincz M.D. Young Clinical Scientists - Joseph P. Laurino, Ph.D. and Terrence N. Moyana, M.B.

The Banquet Lecture was by Dorothy Bryan who presented "Art as Therapy: The 'Chemo' Series" a series of paintings done by a patient who was undergoing chemotherapy at the time.

The Association of Clinical Scientists - 1994

Meeting Number 105. - May 11-15, 1994; Lodge Alley Inn and Medical University of South Carolina, Charleston, SC

Meeting Number 106. - Nov 16-20, 1994; Holiday Inn Crowne Plaza, Tampa, FL (Clinical Science of Aging)

President - Peter J Goldblatt MD

Vice-President - Sidney M Hopfer PhD

Secretary-Treasurer F William Sunderman Jr MD

Auxiliary President - Christine Vlahides

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR John Lazarchick MD

DIPLOMA OF HONOR Bernard Gondos MD

YOUNG CLINICAL SCIENTIST AWARD Kathleen A Allen MD

ABRAHAM J GITLITZ MEMORIAL LECTURESHIP Harry S Margolius MD "Kinins: Modulators of Vascular Resistance and Blood Pressure."

Awards for outstanding Contributions - Filiberto Cavazos M.D. and Martha-Lee Sunderman.

Meeting Number 105. - May 11-15, 1994; Lodge Alley Inn and Medical University of South Carolina, Charleston, SC

The Spring Meeting was held on May 11-15, 1994 at the Lodge Alley Inn, under the sponsorship of the Medical University of South Carolina, Charleston S.C.

The Abraham J. Gitlitz Memorial Lectureship was given by Harry S. a Margolius M.D. and was entitled "Kinins:Modulators fo Vascular Resistance and Blood Pressure".

The traditional Tour was of Charleston's historic district and showed us many of the old buildings with their fascinating histories.

The Reception and Banquet was held at the Great Hall of the Old Exchange, an absolutely fascinating building. The Banquet Speaker - Dr. W. Curtis Worthington -"The Man who killed Warrington Dawson".

Under the direction of Dr. Muschenheim - the ad hoc chairman of the cravat committee, the new red necktie was made available for first time. The Musicale was held in the brick hall across the alley from the rest of the Lodge. This building was brick on the inside also; so the sound was deafening when brass instruments were played. The string selections were heard well.

Meeting Number 106. - Nov 16-20, 1994; Holiday Inn Crowne Plaza, Tampa, FL (Clinical Science of Aging)

The Fall Meeting was held at the Holiday Inn Crowne Plaza, Tampa FL. The title was the "Clinical Science of Aging". The usual tour was of "Historical and Modern Tampa" President Peter Goldblatt M.D. presided at the banquet. The Banquet Speaker was Nicholas R.S. Hall Ph.D. who gave a fascinating talk on "Arts, Health and Immunity".

Association of Clinical Scientists: History 1995-1997

These past three years of the ACS history have been very exciting and, as in previous years, productive, enlightening, and thoroughly enjoyable by all who regularly participate in the many excellent professional and social opportunities. The members are all warm friends and wonderful colleagues. Truly, it is a great pleasure and honor to be associated with such outstanding professionals and their spouses.

As we look forward to the gala event in Philadelphia in November 1998 to celebrate our founder's 100th birthday, we nevertheless recognize that several important "road blocks" have been placed in our way and that we must rise and overcome them.

These past three years have probably been a little more "bumpy" than before since a couple of critical items have arisen; they have only partially been resolved. A major problem is the CME accreditation for Category I credit due to the now pervasive inspection bureaucracy (See Muschenheim F., ACCME--A Burdensome Bureaucracy, Ann Clin Lab Sci 1996;26:192-3). That is, our evaluation by the National Committee fell short in a couple of areas. Importantly, the financial cost of the CME program is considerable, not to mention the time involved by Association members to make the needed improvements. As a result, several stop-gap measures have been taken including formation of an Education Committee chaired by Gregory S. Makowski. We paid the initial sum to secure our program for two years and have investigated possible options to offer CME credit (ie, contacted ASCP, CAP, etc). However, these do not appear realistic nor does an association with the local university where meetings are held. As of Spring 1997, this issue is still with us but it is being addressed.

Another item of importance is the question of whether we should have only one meeting each year instead of two. A distinct possibility is to eventually eliminate the Fall meeting and extend the Spring meeting by 1-2 days. The major problem leading to this consideration is cost; personal finances due to "managed care" and reduced availability of funds to many Association members for travel and education are serious. This is particularly true since many members also belong to, and should support, other societies (ASCP, CAP, AACC, ASM, IAP, AABB, etc). Furthermore, our declining membership is also, at least in part, due to financial matters. Unfortunately, this is occurring at the same time that our "core" membership is aging. Nevertheless, we are somewhat optimistic that these problems will be successfully resolved.

The Association of Clinical Scientists - 1995

Meeting Number 107. - May 10-14, 1995; Houston Plaza Hilton Hotel, University of Texas - MD Anderson Cancer Center; Houston, TX

Meeting Number 108. - June 11-14, 1995; 12th International Conference on Human Tumor Markers, New York Hilton, New York, NY.

Meeting Number 109. - July 10-13, 1995; Vth COMTOX Symposium on Toxicology and Clinical Chemistry of Metals; University of British Columbia, Vancouver, B.C., Canada

Meeting Number 110. - Oct 25-29 1995; Holiday Inn Crowne Plaza, Redondo Beach, CA. (Immunologic Techniques for Diagnosis, Transplantation, and Therapy)

President - Sidney M Hopfer PhD

Vice-President - Joseph A Knight MD

Secretary-Treasurer F William Sunderman Jr MD

Auxiliary President - Pauline Knight

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR James T Wu PhD

DIPLOMA OF HONOR Peter M Farmer MD

YOUNG CLINICAL SCIENTIST AWARD Gregory S Makowski PhD

CLAUDE P BROWN MEMORIAL LECTURESHIP Armand Glassman MD "Cytogenetics, Gene Fusions, and Cancer."

Meeting Number 107. - May 10-14, 1995; Houston Plaza Hilton Hotel, University of Texas - MD Anderson Cancer Center; Houston, TX

The Spring meeting (Frontiers of Clinical Science, May 10-14) was sponsored by Armand Glassman M.D., at the University of Texas M.D. Anderson Cancer Center in Houston. The host hotel was the Houston Plaza Hilton, an excellent facility.

The Claude P. Brown Memorial Lecture entitiled "Cytogenetics, Gene Fusions, and Cancer" was given by Dr. Glassman. In addition, several excellent keynote lectures by faculty of the University of Texas were given (Drs. S. Sell, S.S. Wong, D. Yawn, A. Killary, and M-S. Lee). Each section was followed by excellent up-to-date talks by Association members.

Special education programs and sectional luncheon speakers included the following. Surgical Pathology Tutorial (Ruth Katz M.D., "Aspiration Cytology of Breast Cancer"); Therapeutics and Toxicology (Alan H. Wu PhD, "Evidential Breath and Salivary Ethanol Testing"); Clinical Science in Practice (P.R. Gilmer Jr., "CAP Laboratory AccreditationProgram"); and Clinical Biochemistry and Biotechnology (Dr. H.A. Fritsche, "Update of ProstaticTumor Markers").

As usual, the Musicale/Art Show was outstanding. It was organized by Dr. Bernard Gondos. The Reception and Banquet was held on Saturday evening. Carolyn Huntoon, Director of the Johnson Space Center, gave an excellent talk on the space program. The meeting also featured a special tour of the Johnson Space Center, an event greatly enjoyed by those able to attend. In addition, a tour of the museum district included the Houston Museum for Natural Science which has a fantastic collection of live butterflies. We were able to walk through the museum and observe the butterflies as if they were in our own back yard. For the physically active members, the Run for the Lillies and Walking Tour on Sunday morning around the campus of Rice University was enjoyed by all participants.

Meeting Number 108. - June 11-14, 1995; 12th International Conference on Human Tumor Markers, New York Hilton, New York, NY.

The 12th International Conference on Human Tumor Markers was held at the New York Hilton and Towers in New York City June 11-14, 1995. Dr. John Klavins and the Catholic Medical Center of Brooklyn and Queens hosted the meeting in conjunction with the International Academy of Tumor Marker Oncology. The Association of Clinical Scientists was a co-sponsor. The program included presentations on oncogenes and tumor suppressor genes, cytokeratines, tumor-specificity of markers, markers for cancer development and metastases, and tumor therapy.

Meeting Number 109. - July 10-13, 1995; Vth COMTOX Symposium on Toxicology and Clinical Chemistry of Metals; University of British Columbia, Vancouver, B.C., Canada

The Vth COMTOX symposium on "Toxicology and Clinical Chemistry of Metals" was held July 10-13, 1995 at the University of British Columbia in Vancouver, B.C., Canada. This international meeting was organized by the Association of Clinical Scientists (F. William Sunderman Jr., M.D.); there were several co-sponsoring organizations. The major program themes were: (1) Analysis of Metals in Biological Materials, (2) Molecular Biology and Toxicology of Metals, (3) Metals in Health and Disease, and (4) Occupational and Environmental Exposures to Metals. The meeting was attended by more than 400 scientists from over 65 nations, including several of us representing the Association. The meeting and accommodations were very well organized and a great learning experience for the attendees. In addition, Vancouver offers many exciting things to do.

Meeting Number 110. - Oct 25-29 1995; Holiday Inn Crowne Plaza, Redondo Beach, CA. (Immunologic Techniques for Diagnosis, Transplantation, and Therapy)

The Applied Seminar and Workshops ("Immunologic Techniques for Diagnosis, Transplantation, and Therapy") was held at the Holiday Inn Crowne Plaza, Redondo Beach, CA (October 25-29, 1995). The host committee was co-chaired by Byron Myhre, M.D., Ph.D. and Paul Fu Ph.D. The meeting site was beautiful and very relaxing. The writer of these words was very impressed with, and grateful for, the superb exercise facilities.

Beckman Instruments Inc hosted the Association at their Fullerton CA facility on Friday, October 27. The day was well spent and Beckman was a very gracious host. They provided excellent speakers on several relevant topics, held several workshops, and treated members to an excellent luncheon out-doors under a tent. The luncheon speaker, James Osborne PhD, talked on "Frontiers in Genetic Testing: Genosensor Diagnostics".

The Seminar was very informative and many pertinent talks were given by Association members. In addition, the luncheon speakers sponsored by the various sections were: Clinical Science in Practice (Peter Howanitz M.D.; "The Past, Present, and Future of Q-Probes"); Toxicology and Therapeutics (James McBride Ph.D., "Toxicology at UCLA").

The banquet speaker was Charles Rene M.D.; he gave a very fascinating presentation entitled, "Marine Mammal Medicine." In addition, several members were recognized for their excellent contributions: James T. Wu Ph.D. (Clinical Scientist of the Year); Gregory S. Makowski Ph.D. and Linda Steel-Goodwin Ph.D (Young Clinical Scientist Awards); and Peter M. Farmer M.D. (Diploma of Honor).

The Musicale /Fine Art Show was outstanding and enjoyed by everyone. Our heartfelt thanks go to Dr. L.H. van der Hoeven, the organizer of the event. As usual, the intermission cheese and wine (and "cokes" for others) were greatly enjoyed.

The Association of Clinical Scientists – 1996

Meeting Number 111. - May 1-5, 1996; The Carolina Inn; University of North Carolina Medical School, Chapel Hill, NC

Meeting Number 112. - June 16-19, 1996; 13th International Conference on Human Tumor Markers, Shangri-La Hotel, Singapore

Meeting Number 113. - Oct 30 - Nov 3 1996; Seelbach Hotel, University of Louisville Medical School, Louisville, KY, [Neurologic and Psychiatric Diseases: Molecular Basis and Diagnostic Approaches]

President - Joseph A Knight MD

Vice-President - James T Wu PhD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR Frederick L Kiechle MD PhD

DIPLOMA OF HONOR George D Vlahides MD

YOUNG CLINICAL SCIENTIST AWARD Gregory Tsongalis PhD

ABRAHAM J GITLITZ MEMORIAL LECTURESHIP Kenneth M Brinkhous MD "Hemophilia: Perspectives on the Evolution of Understanding and Management from 1935 to 1996."

Meeting Number 111. - May 1-5, 1996; The Carolina Inn; University of North Carolina Medical School, Chapel Hill, NC

The Spring 1996 meeting (Frontiers of Clinical Science) was hosted by Don and Florence Forman in Chapel Hill, NC, "the southern part of heaven" (May 1-5, 1996). Hotel accommodations were at the historic and very comfortable Carolina Inn; the scientific sessions were held in an auditorium of the University of North Carolina School of Medicine.

The Abraham J. Gitlitz Lecture was given by Dr. K.M. Brinkhaus ("Hemophilia-Perspectives on the Evaluation of Understanding and Management"). Excellent keynote lecturers were Drs. M.R. Knowles, O. Smithies, and R.M. Nakamura. Each session was followed by excellent platform presentations by Association members and guests. Several luncheon and other education programs included the following: Clinical Science in Practice (Paul Bachner M.D., "Money Changers in the Temple: The Changing Practice of Pathology and Laboratory Medicine"); Therapeutics and Toxicology (Dr. John Butts, "Arsenic Poisoning"); Clinical Biochemistry and Biotechnology (Dr. Ellis Jacobs, "Update on the Provision of Critical Laboratory Services"). The surgical pathology slide seminar ("Pathology of the Liver") was conducted by J.T. Woosley M.D. while the Clinical Science in Practice Tutorial, presented by Dr. J.E. Hammond, was "Clinical Workstation and Computer-Based Medical Records: The Carolina Experience 1991-1996".

On Thursday evening (May 2), we were treated to a wonderful "Carolina Barbeque" at the Carolina Club of the University of North Carolina. On Friday, a group of participants visited Glaxo Wellcome's Research and Development facility where they were treated to a program entitled, "Drug Discovery, Formulation, Metabolism, and Safety." In addition, on Friday afternoon many of us went on a wonderful tour that included the Dean Smith Center ("Dean Dome"), Duke University Primate Center (highly interesting), the Sarah P. Duke Gardens, and the beautiful Duke University Chapel and adjacent buildings (reminiscent of England). It was truly a fabulous afternoon!

The Association Reception and Banquet featured not only excellent food and drink, but author Doris W. Betts gave a stimulating talk entitled "A Southern Writers View of Life." She received a very warm and well-deserved applause by the audience. On Saturday evening, the Association Musicale and Art Show, organized by Dr. Bernard Gondos, was held. As usual, the program was greatly appreciated and enjoyed by all. Intermission wine and cheese (and soft drinks) were welcomed.

On Sunday morning, the Run for the Lillies around the UINC campus was very nice. Participants received appropriately colored (UNC "blue") and labeled T-shirts graciously provided, as usual, by our dear friend and colleague Filiberto Cavazos M.D. Dr. Cavazos has personally designed, bought, and given these memorable shirts to participants of this event for several years. His sincere interest and thoughtfulness are greatly appreciated by all.

Meeting Number 112. - June 16-19, 1996; 13th International Conference on Human Tumor Markers, Shangri-La Hotel, Singapore

Meeting Number 113. - Oct 30 - Nov 3 1996; Seelbach Hotel, University of Louisville Medical School, Louisville, KY, (Neurologic and Psychiatric Diseases: Molecular Basis and Diagnostic Approaches)

The Fall Applied Seminar was on "Neurological and Psychiatric Diseases: Molecular Basis and Diagnostic Approaches".  The meeting was co-hosted by J.C. Parker Jr. M.D. and R. Valdes Jr., Ph.D. of the University of Louisville School of Medicine. The host hotel was the Seelbach, an historic beautiful hotel in downtown Louisville. The hotel is within easy walking distance of many restaurants, shopping mall, etc. The program was superb and featured numerous exciting topics and excellent speakers.

The various luncheon speakers and the topics of the several sections were: Clinical Science in Practice (Irene Roeckel M.D. "In Love with Quality"); Therapeutics and Toxicology (Roland Valdes Jr., Ph.D., "New Analytical Strategies in Therapeutic Drug Monitoring"); Clinical Biochemistry and Biotechnolgy (Donald Cannon Ph.D., "Laboratory Medicine and Neurological Diseases); and Cell and Tissue Pathology (R.A. Omar M.D., Tutorial on CNS Pathology).

The Reception and Banquet were held in the beautiful unique ballroom of the Seelbach Hotel. Here, Dr. Thomas L. Owen, Professor of Libraries at the University of Louisville, gave a very interesting presentation on "Reflections of Louisville." Also on that evening, the following members were recognized: Frederick Kiechle M.D., Ph.D. (Clinical Scientist of the Year); George Vlahides M.D. (Diploma of Honor); and Gregory Tsongalis Ph.D. (Young Clinical Scientist).

On Friday afternoon, many members and their spouses visited the famous Churchill Downs and watched the horse races. Word has it that some won a little and some lost a little. The tour also included the Kentucky Derby Museum. Others visited the fantastic newly opened Louisville Slugger Museum which was within easy walking distance of the hotel. This was truly a unique experience where one can watch the skilled employees make a wide variety of Louisville Slugger baseball bats. One can also purchase an official personalized bat (a great gift for a son/daughter or grandchild). Many other exciting displays were also present. Future visitors to Louisville must not forget to visit this Louisville treasure!

Miscellaneous 1996 Events

Other noteworthy events of this year included the following: (1) Resignation of F. William Sunderman Sr. M.D., Ph.D. as Director of Education of the Association of Clinical Scientists. As a result, Dr. F. William Sunderman Jr. accepted managerial responsibility for the Association's CME activities in his capacity as Secretary-Treasurer. (2) Recognition of Helen M. and Alfred H. Free for their outstanding contributions to techniques for clinical analysis. For this, they were enshrined in the Engineering and Science Hall of Fame in Dayton, Ohio. (3) On February 6, 1996 the Executive Committee held its first teleconference. This was not only very successful, but it saved several thousand dollars on transportation, food, and hotel costs. Nice going Bill Jr.!

The Association of Clinical Scientists – 1997

Meeting Number 114. - May 6-9, 1997; Salt Lake City, Utah

Meeting Number 115. - Nov. 6-9, 1997; Emory Conference Center, Emory University, Atlanta, GA.

President - James T Wu PhD

Vice-President - Joseph P Laurino PhD

Secretary-Treasurer F William Sunderman Jr MD

RECIPIENTS OF AWARDS OF THE ASSOCIATION OF CLINICAL SCIENTISTS

CLINICAL SCIENTIST OF THE YEAR – Paul C. Fu, Ph.D.

DIPLOMA OF HONOR – Joseph A. Knight, M.D.

YOUNG CLINICAL SCIENTIST AWARD – Daniel D. Sedmak, M.D.

CLOUD P. BROWN MEMORIAL LECTURESHIP – Joseph A. Knight, M.D.

 “Free Radicals, Aging, and Disease”.

Meeting Number 114. - May 6-9, 1997; Salt Lake City, Utah

The 1997 Spring meeting was held May 7-11 at the University Park Hotel, which is adjacent to the University of Utah in Salt Lake City. The meeting was co-chaired by James T. Wu and Joseph A. Knight.

The keynote speakers were: T. Fuller ("Current Status of Bone Marrow Transplantation"), J. Holden ("Human DNA Topoisomerases: Molecular Targets of Anticancer Drugs"); J.T. Wu (PSA and Free PSA in Prostate Carcinoma"); M. Skolnick ("Breast Cancer Susceptibility Gene"); F. Clayton (G.I. Manifestations of HIV Infection"); L. Wu (Homocysteine as a Risk Factor in Cardiovascular Disease"); J. Knight (Free Radicals, Aging, and Disease"); R. Daynes ("Dysregulated Expression of Cytokines with Aging: Molecular Mechanisms and Therapeutic Correction").

The section luncheon speakers and topics were: Therapeutics and Toxicology (F.M. Urry, "Analysis and Clinical Applications of Three New Anticonvulsants: Felbamate, Gabapenin, and Lamotrigine"); Clinical Science in Practice (John M. Matsen, University of Utah Vice President for Medical Affairs, "Managed Care and The Clinical Laboratory"). Dr. Cheryl Coffin conducted a surgical pathology tutorial on soft tissue tumors while Dr. C. D. Hawker spoke on "An Automated System for Transporting and Sorting Laboratory Specimens".

On Friday afternoon, a tour of the Park City Silver Mine included a descent of 1,500 feet into the mine and travel by train through 3,200 feet of tunnel. It was a very exciting and interesting event. At the Friday evening Reception and Banquet, J.P. Hughes M.D. gave an entertaining talk, "Trial, Trail, and Temple". This topic is of significance since 1997 marks the sesquicentennial year of the Mormon pioneers settling the Salt Lake Valley. Dr. Hughes discussed their trek from Illinois across the plains to the Utah Territory, several ghost towns of Utah, and other interesting historical events of Utah.

The Spring meeting in Salt Lake City will remain memorable for its rich program and the excellent hospitable facilities enjoyed at the University of Utah campus.  The local organizing committee, Drs. Joe Knight, James and Lily Wu, Charles Hawker, and Juliana Szakacs brought the best of talent available in Utah to enhance the scientific and social program.  Forty-seven papers were presented in addition to Dr. J. Matsen’s luncheon address:  “Managed Care and the Clinical Laboratory”.  His address was a wake-up call to the opportunities for clinical scientists to take advantage of the rapidly changing environment of managed care.  His upbeat exhortation  was quite different from the pervasive gloom settling on the laboratory community in recent years.  His optimism for the future was quite convincing noting the success of ARUP Laboratories at the University of Utah.

True to tradition of the Association, the members visited the host institution’s facilities, the ARUP Laboratories, under the guidance of Dr. Hawker.  The new facilities were toured highlighting the areas of specialized methods and automatic instrumentation.  All the visitors were impressed by the skillful organization of this very successful scientific enterprise.

Another remarkable event on the program was the surgical pathology tutorial presented by Dr. Cheryl M. Coffin.  Diagnostic Challenges in Pediatric Tumor Pathology was of the highest caliber beautifully illustrated with well selected cases complete with a useful text and bibliography.

The social programs included the Association Reception and Banquet at the University Park Hotel with Dr. James T. Wu presiding.  The delightful Association Musicale and Art Show on Saturday evening organized by B. Gondos, Pauline Knight and the Fine Arts Committee was much enjoyed by all.  The hardy ones entered the “Run for the Lilies” early Sunday morning on 1.5 or 5 Km courses around the University Campus.

The meeting concluded with a planning session presided by Dr. Robert L. Hunter for the Applied Seminar on “Laboratory Diagnosis of Disorders of the Gastro-intestinal Tract” to be held in Atlanta, GA on November 5-9, 1997.

The 14th International Conference of Human Tumor Markers was held at the Holiday Inn Crowne Plaza Hotel in Jerusalem, Israel, June 15-19, 1997. Dr. John Klavins, President of the International Association of Tumor Marker Organizations (IATMO), is a past president of the Association of Clinical Scientists. The conference was organized by IATMO, with cooperation from the ACS.

Meeting Number 115. - Nov. 6-9, 1997; Emory Conference Center, Emory University, Atlanta GA.

The Association of Clinical Scientists – 1998

President - Joseph P Laurino PhD

Vice President - Frederick L Kiechle MD, PhD

Recording Secretary – Federick Muschenheim, MD

Secretary-Treasurer - F William Sunderman Jr MD

Meeting Number 116 – April 29 – May 3, 1998; Biltmore Hotel, Brown University School of Medicine, Providence, RI.

The Executive Committee held a long exhaustive meeting analyzing the strengths and weaknesses of the Association.  While obvious strengths are evident in exceptional breadth of scientific topics covered in the Association’s meetings and shared enthusiasm of the members, including music, travel and social activities, challenging weaknesses are seen in the aging of membership and in the proliferation of competing meetings by other organizations.  A long list of considerations were suggested to strengthen the Association in various areas of concern.  Great praise was given to the Annals and its Editor, Dr. Sunderman, Sr. who guided it through 28 years of excellence.

The meeting then took up planning for the Centenary Birthday Party for Dr. Sunderman, Sr.  Mrs. Martha Lee Sunderman and Bill Sunderman, Jr. led the planning.  The scientific program to be titled “Clinical Science in the New Millenium:  The Past is Prologue”.  The submitted manuscripts to form a Festschrift Volume for presentation to Dr. Sunderman, Sr.

Meeting Number 117 – October 21-23, 1998; Doubletree Hotel, Jefferson Medical College, Philadelphia, PA (Clinical Science in the New Millenium:  The Past is Prologue)

This meeting was planned with great care and love by Martha Lee Sunderman and F. William Sunderman, Jr. to celebrate the Association’s 50 years of existence and its founder’s 100th Birthday.  They were assisted in their efforts by the 1998 Fall Meeting Committee whose members chaired the 10 scientific sessions.  The meeting format was changed to better serve the educational objectives of this festive event to present the current status of scientific knowledge and envision likely prospects for future developments in tissue pathology, clinical chemistry, genetics, molecular biology, toxicology, microbiology, biotechnology, informatics, and clinical science in practice.  Each presentations was allowed 30 minutes.  All manuscripts were previously submitted to form the Festschrift Volume and were later published in the Annals.

Sadly, Martha Lee Sunderman did not live to participate in the festivities.  She died on September 26, 1998 working to the last for the success of the planned Centenary Birthday Celebration for Bill Sunderman, Sr.  Martha Lee’s many friends and admirers were able to attend the memorial service for her on Thursday, October 22, bringing back memories of Martha Lee’s cheerful efficient help with publications, programs, social events, and her art at Association Musicales and Art Shows.  This exceptional Lady remains much loved and admired by members of the Association.

The meeting was opened by greetings of the Association’s President, Joseph P. Laurino and the guests were welcomed by Dr. Rex B. Conn, our Philadelphia host on Thursday morning.  The clinical biochemistry session began with Dr. Joseph A. Knight’s presentation on the role of free radicals in aging, neoplasia and degenerative diseases and continued on with papers on biotechnology and informatics by several pillars of the Association, Andy Lorincz, Bob Hunter, Jr., Bradley Copeland, and others.

The luncheon meeting of the section on clinical science in practice led by Dr. Fred Muschenheim featured an address by Dr. P. Raslavicus titled “Clinical Science:  Prospects, Payments and Public Policy”, a well received informative talk.

The afternoon was left free so that members who missed Martha Lee Sunderman so much could attend the memorial service for her at the Holy Communion Lutheran Church in Philadelphia.

Friday, October 23, the meetings were held at Thomas Jefferson University’s Connelly Auditorium.  The presentations were highly polished jewels in the best tradition of the Association.  Most were subsequently published in the Annals of Clinical and Laboratory Science.  Dr. Fred L. Kiechle and L. L. Wu chaired a session on clinical molecular biology.  Dr. Kiechle’s paper most appropriately was titled “The Molecular Pathology Laboratory for the Twenty-first Century”.  Other outstanding presentations followed, presented by D. D. Sedmak of Ohio, Fred Muschenheim of NY, Armand Glassman of TX, James T. Wu of UT and F. Forouhar of CT.

A joint luncheon of the sections on clinical molecular biology and genetics and on clinical biochemistry and biotechnology chaired by Drs. Fred L. Kiechle and Paul C. Fu featured Dr. Sydney M. Hopfer who spoke on “Cystic Fibrosis:  Molecular Approaches for Diagnosis”.

Two more scientific sessions were held in the afternoon:  Clinical Science in Practice chaired by Drs. F. Muschenheim and Juliana Szakacs and Clinical Immunology and Microbiology chaired by Drs. Robert J. Hunter, Jr. and Armand B. Glassman.  Dr. Rex B. Conn spoke on “The Influence of Social Factors on Laboratory Medicine followed by several timely subjects closing with discussion of “Murine Antibodies and Human Antigens” by Dr. J. A. Laurino, President of the Association.

Highlight of 117th meeting was the annual banquet:  A Gala Celebration for F. William Sunderman, Sr. on his 100th birthday held at the Union League of Philadelphia on Friday evening, October 23.  The festively decorated hall and the formally attired 400 guests were the proper setting to celebrate the liftetime achievements of Dr. Sunderman, Sr.  The elaborate program attached speaks for itself.  The Association shares the activities of Bill Sunderman, Sr. with other learned societies, the Union League of Philadelphia and his beloved Curtis Institute of Music.  They all had representatives to comment on his influence and achievements.

Founding members of the Association of Clinical Scientists, although somewhat thinned by time, cheered the founder and first president of their beloved Association.  There was Vern Martense with his wife, Lou, Herb Derman, Jim Humes, Bradley Copeland, Irene Roeckel, William Delaney, Jeno Szakacs, and possible others.  This F.F. for one has much to thank Bill Sunderman, Sr.  His encouragement and guidance to participate in the Association’s workshops, meetings and publications helped to form his carreer from resident in pathology to Emeritus Professor.  The constancy of his maintaining contact with each member through the years, the special Christmas cards, the publication of workshop proceedings and manuals, and 30 years of the Annals is a truly admirable achievement.

On Saturday, October 24, the meeting proceeded at the Double Tree Hotel with sessions on hematology and transfusion medicine chaired by Drs. Robert E. Brown and J. Lazarchick with papers presented by Drs. Irene Roeckel, Ed Morse and S. Narayanan.  The session on trace metals in health and disease was chaired by Drs. John Savory and F. William Sunderman, Jr.  Dr. Donald J. Cannon presided at the luncheon meeting of the Section on Therapeutics and Toxicology.  The discussion was titled “Toxicology, Past, Present and Future” and was presented by A. Pappas, NA Massoll and DJ Cannon.

On Saturday afternoon, there were two more sessions:  Cell and Tissue Pathology and Therapeutics and Toxicology.  The outstanding papers of these sessions appear in Vol. 29 of the Annals.  The younger contributors to these programs, TN Moyana and second generation member of the Association, Juliana Szakacs gave outstanding accounts of tissue pathology together with papers by the chair, B. Gondos and Peter M. Farmer.

The musicale and art show on Saturday evening featured a program of chamber music and an exhibition of art by the Association’s members and guests, organized by Bernard Gondos.  A special event was the premiere performance of a string quartet composed by B. Gondos and dedicated to F. W. Sunderman, Sr. which had great success.

Sunday, October 25th in the morning, the open business meeting was held, followed by a meeting of the Scientific Council to plan the Association’s spring meeting in Columbus, OH.

The 117th meeting of the Association of Clinical Scientists marking its 50th year and its founder’s 100th birthday celebration was a great success both scientifically and socially.  Each and every member of the Program Committee is thanked, and is here recorded.

Program Committee for the 1998 Fall Meeting:

F. William Sunderman, Jr., MD, Chair     Robert L. Hunter, MD, PhD

Robert E. Brown, MD                                  Donald L. Jungkind, PhD

Donnald J. Cannon, MD                             Frederick L. Kiechle,  MD,PhD

Rex B. Conn, MD                                         Joseph P. Laurino, PhD

William E. Delaney, MD                              Frederick Muschenheim, MD

Paul C. Fu, PhD                                           MarthaLee Sunderman(deceased)

Bernard Gondos, MD

The Bermuda Connection

A special privilege of fellowship in the Association of Clinical Scientists in the last few years has been participation in the field trips to the Biological Station for Research in Bermuda.

The genesis of these trips lies in the long-standing connection between Dr. F.W. Sunderman Sr. and the "Bio Station". He first traveled there in 1927 to study electrolytes in sharks and lobsters. He was elected to the Board of Governors in the 1960's, and continues as a Governor Emeritus.

Since 1984, the Bermuda field trips have been a biennial activity in the spring of even numbered years, with enthusiastic participation by fellows of the Association and other invited participants, abetted by the warm hospitality of the Bio Station staff.

Days on these trips are spent on various scientific and cultural activities, and evenings are highlighted by lectures from the scientific staff.

Cultural activities have included visits to the Lord Mayor of Hamilton, to Parliament, and to the Premier of Bermuda. In 1990, those in attendance received training in riot control from the Bermuda Regiment, and in 1994 the group was treated to a tour of historic St. George's at the eastern end of the Bermuda islands, with a visit to the town hall and the town manager, Margaret Emmott.

Scientific activities usually include an evening plankton tow in St. George's harbor, with microscopic examination in the laboratory of the specimens obtained. Visits to the Bermuda Aquarium provide an opportunity to review the names and characteristics of marine species in preparation for snorkeling trips to various destinations. These have included the reefs along the "pink beaches" on the south shore and entirely different fauna in Harrington Sound. Joe Laurino has not yet recovered from his face-to-face encounter with a cowfish there. In 1996 favorable weather conditions permitted the most spectacular snorkeling trip, to North Rock, near the edge of the Bermuda atoll.

A regular event is a trip to Nonsuch Island, Bermuda's nature reserve, where David Wingate has spent a lifetime reconstructing the flora and fauna of the islands before the arrival of man. Trip participants have had the opportunity to watch the growth of this project over the years. Standing on the plateau on Nonsuch, where Dr. Wingate maintains his demonstration nesting area for the rediscovered Bermuda cahow, permits an incredible view of Castle Harbour. To the east is the airport and the former US naval base. To the west is the ruined castle from the era of Charles the Second, the Castle Harbor hotel, and three-house complex where Ross Perot maintains his off-shore residence. Bermuda longtails make their nests in the cliffs below, and can be seen in graceful flight over the clear blue waters. On the other side of Nonsuch, a beautiful beach is the site where Dr. Wingate has released turtle hatchlings in hopes of reestablishing their nesting ground. The welcome at Nonsuch is all the warmer since Dr. Sunderman has known Dr. Wingate all his life, having played quartets with Dr. Wingate's father.

When trips have coincided with the lunar cycle, the participants have made evening excursions to the west end of Ferry Reach, near the Station, to observe the dazzling luminescent display of the unique Bermuda fireworms. Their activity is at its peak on the fifth night following the full moon.

Many of the evening scientific lectures have been memorable. They have included such topics as algal-coral symbiosis, the geology of Bermuda and reading the history of weather in its limestone, world climatology and the prediction of hurricane cycles, and a workshop on coral identification. Trip participants have also shared their expertise with the group. Especially notable was the colorful demonstration of marine microbiota with acridine orange under fluorescence microscopy by the always prepared Dr. Andrew Lorincz.

The highlight of all the trips occurred in 1992, when the most actively used classroom at the Station was dedicated as the Sunderman Seminar Room in honor of Bill Sunderman Sr. and Martha-Lee. The Governor-General of Bermuda, Sir Desmond Langley and Mrs. Langley, officiated at the dedication and official opening of the room, followed by a reception for the public.

The Sunderman Seminar Room project had its origin in an idea germinated by Kendall Kane and Barbara Lowry during the preceding trip in 1990, to commemorate in a permanent fashion the group's gratitude to Bill and Martha-Lee for sharing their love of Bermuda and the Station with the participants. A fund was established to refurbish, furnish, and equip the room. The Fund is continuing to maintain the room, through the generosity of the participants and other friends of the Sundermans. The effort has been greatly appreciated by the staff and visitors to the Station, who have frequently expressed their gratitude for the equipment and furnishings in this heavily used room. It is hoped that a large enough endowment will be generated in the future to provide scholarship support for students visiting the Station as well as maintaining the Sunderman Seminar Room.

Participants have had the opportunity for a lot of fun during the field trips. Humor has been an important part of each trip. Raconteurs George Vlahides, Brooks Hurd, and Rich Wasson always have a new joke to tell at the "dark and stormy" get-togethers before dinner, so named for the featured concoction of Gosling's Bermuda Black Rum and ginger beer. Don Forman's magic acts have been a source of much mirth. He and other participants were recorded on tape in 1994 for the entertainment of then-ailing Kendall Kane.

The trips have always allowed time and opportunity for shopping, tennis, and other activities, both in St. George's and in Hamilton. A favorite afternoon activity has been snorkeling in the protected waters in and around Tobacco Bay, north of St. George's, where the fauna includes large, colorful parrotfish, beautiful Bermuda blue angelfish, and Faripour Farouhar in a wet suit.

The trips have also not been without untoward events, especially related to the use of mopeds. An earlier trip in 1974 was marred by the death in a moped accident of Abraham Gitlitz. A lectureship at Association meetings honors his memory. Sporadic minor accidents have occurred in more recent trips. As Bermuda's population has grown, the number of cars on the road has increased while the traditional courtesy displayed by drivers to mopeders has declined. Many of the group now eschew the use of mopeds in favor of the excellent bus system and plentiful, inexpensive taxicabs.

The Bermuda field trips have been enjoyed by all participants. Because many of the travelers return trip after trip, a nucleus of good friends has developed among those who have shared the experience. This bonding has provided strength to the Association of Clinical Scientists as a whole.

Music and the Arts

Music, especially chamber music concerts have been an important activity of the society. In October 1981 at the Fall Meeting in the Barclay Hotel in Philadelphia, F. William Sunderman, Sr. wrote the following:

"Ever since college days, chamber music has been for me the most appealing form of music for listening and the most demanding for playing. In many ways, the demands for playing chamber music are greater than that of solo performance. The chamber music player must acquire techniques for instantaneous adjustments and achieve high degrees of flexibility. I have on one occasion played with a renowned artist who had played the Sibelius violin concerto flawlessly the previous week with one of the major symphony orchestras and yet who had much difficulty reading and playing accurately the phrases of the D minor Mozart Quartet. In a string quartet, the various musical items are distributed among performers so that at any given moment a player may be a soloist or an accompanist. Therefore, each part must be fitted together like a mosaic and must be subtly bound, with each player contributing toward a musical balance. For satisfactory performance, string quartet players must weld themselves into a homogenous unit. It is the mastery of such ensemble playing that offers an endless challenge and, if done well, generates the joy of accomplishment. Many musical enthusiasts prefer the intimacy that chamber music provides to that of the larger musical forms in which the rapport between performers and audience is lost in the large concert hall. It is also noteworthy that most chamber music players would rather play themselves than listen to others. In all of my adult life, I have found it to be relaxing beyond measure to set aside the perplexing problems of the day and to make music with congenial friends in the evening. Part of the exhilaration that comes from ensemble playing is the sparkling conversation that usually develops during quartet sessions. These frequently pertain to the composers' lives; the circumstances under which the compositions were written; the technical skills and musical interpretations of outstanding performers; the merits of various instruments, bows, etc. All such topics are remote from the labors of the day; however, when the evening's playing is over, the players are usually refreshed with beautiful melodies floating in relaxed minds and, as a consequence, they are better prepared to solve the problems of the morrow."

Beginning in 1992, several changes occurred in the types of presentations at the Association Musicale. The changes reflected both the creative activities of members of the organization and artistic accomplishments in areas of the fine arts other than music. The events now began to include exhibits of paintings, photographic work, sculpture and artefacts.

At the November 1992 meeting in Santa Barbara, a composition by Bernard Gondos for two violins and cello was performed by the composer, Carolyn Jean Dupuy and Raymond Dorio. The enthusiastic response of the audience at the Musicale played a major role in encouraging Bernie to continue his compositional activities. A recording of his first string quartet was heard at the May 1994 meeting in Charleston and he and Bill Sunderman, Jr. performed his duet for violin and viola at the May, 1996 meeting in Chapel Hill. A special event at the same meeting was the presentation of a video showing Bill Sunderman, Sr. leading the Gettysburg College Concert Band in a march that he had written. This resulted in a rousing response from attendees, in appreciation of Bill's compositional and conducting talents.

Broadening of the scope of artistic activities to include multiple media was in evidence at the May, 1993 meeting in Newport, as has been the case at all subsequent meetings. Consequently, instead of the traditional designation of Association Musicale, the event was now referred to as the Musicale and Art Show. Also in 1993, the Music Committee became the Music and Arts Committee. Exhibitors of art work have included Dot Brown, Mel and Zimmie Davis, Florence Forman, Nelson Gelfman, Diane Lorincz, Martha-Lee Sunderman, Jeno Szakacs and Janet Wasson. The variety of media used and the quality of the work exhibited have both been remarkable.

Also reflecting the increasing breadth of artistic activities was the addition of Jazz performances to the traditional chamber music presentations. Noteworthy was the May, 1995 meeting in Houston when Stewart Sell and his Jazz Medics regaled the audience with a variety of traditional and modern jazz arrangements. Joined by Fritz Kiechle, who had already introduced his own piano improvisations on previous occasions, the group played well on into the evening to the delight of the audience. As a result, it has now become a regular event to have Fritz close out the musical activities with his jazz renditions, often joined by others on their different instruments.

But the emphasis remained on classical chamber music performances. Bill Sunderman, Sr. continued to amaze and enthrall everyone with his violin playing, even as he approached the century mark. He typically would perform a piece for violin and piano with Ludolph van der Hoeven and then close the second half of the program leading a string quartet or piano quartet. The rich viola sound of Bill Sunderman, Jr., playing in various instrumental combinations, was always a special feature of the evening. Jean Cook contributed her delightful solo piano performances, covering the gamut from Chopin to less well known composers such as Dohnanyi and MacDowell . A wide range of musical styles was also presented by Byron Myrhe with arrangements for trumpet and other instruments from the baroque to the contemporary. Many other members and guests contributed their talents on different occasions.

In 1994, the torch was passed from Ludolph van der Hoeven to Bernard Gondos as chair of the Music and Arts Committee. However, since both have continued to take a major part in the activities, planning of the events has remained a joint endeavor. Every effort has been made to include all those who wish to participate.

A special feature of the musical activities has been to encourage the participation of guest artists. Several outstanding musicians have graciously provided their talents and assistance at the events. Particularly notable have been Richard Clark, cellist and radiologist, at the May, 1996 meeting in Chapel Hill, pianist Rosalie Beverly (now a member) and husband Robert Beverly (clarinet) at the November, 1996 meeting in Louisville and cellist Sybil Baker at the May, 1997 meeting in Salt Lake City. These talented musicians have provided the opportunity to present special and unusual works from the musical literature of different periods.